University of Health Sciences Antigua

Prevalence and prognostic significance of obstructive sleep apnea in patients with idiopathic pulmonary fibrosis: A prospective cohort study

ABSTRACT BACKGROUND: Obstructive sleep apnea (OSA) is a recognized comorbidity in idiopathic pulmonary fibrosis (IPF); however, its true prevalence remains uncertain, and its prognostic implications have not been fully elucidated. This study aimed to determine the prevalence of a...

Storage symptom burden in women with obesity is associated more with age and smoking than metabolic biomarkers: prospectively collected cross-sectional data

Obesity frequently coexists with insulin resistance and lower urinary tract symptoms, but the independent contribution of metabolic abnormalities among women with obesity is uncertain. We analyzed prospectively collected cross-sectional data from 139 women with body mass index ≥...

Early mRNA expression of pro-inflammatory cytokines and ADAMTS-5 in an acute ischemia/reperfusion–induced pressure ulcer model, a pilot exploratory animal study

Objectives: This study aimed to determine the messenger ribonucleic acid (mRNA) expression levels of interleukin (IL)-1α, IL-1β, IL-6, IL-17, and A Disintegrin and Metalloproteinase with Thrombospondin Motifs (ADAMTS) -5 in an acute ischemia/reperfusion (I/R)-induced pressure ulc...

Omphalocele with Patent Omphalomesenteric Duct and Intestinal Prolapse in a Preterm Neonate: Histopathological Evidence of Incomplete Vitelline Duct Involution

Patent omphalomesenteric duct (OMD) with intestinal prolapse coexisting with omphalocele is an exceptional ventral folding anomaly that may be misdiagnosed as gastroschisis. The vitellointestinal duct normally involutes between the seventh and ninth gestational weeks; failure of...

Large Language Models Versus Multidisciplinary Tumor Board Decisions in Thyroid Cancer

ABSTRACT Objectives Large language models (LLMs) are increasingly proposed as clinical decision‐support tools; however, their agreement with real‐world multidisciplinary tumor board (MDT) decisions remains insufficiently investigated in thyroid oncology. To evaluate the concordan...

Neutrophil-to-HDL-C Ratio and Anatomically Significant Multivessel Disease Across Acute Coronary Syndrome Phenotypes

Objective: The neutrophil-to-high-density lipoprotein cholesterol ratio (NHR) is an emerging inflammatory-lipid biomarker. Whether NHR is associated with anatomically significant multivessel disease (MVD) across different acute coronary syndrome (ACS) phenotypes remains unclear....

Intermediate-Term Oncological, Anastomotic and Nutritional Outcomes of the Sutureless L-Shaped Esophagojejunostomy with Endoscopic Assistance (SLEJ) in Totally Laparoscopic Total Gastrectomy: A Follow-Up Analysis of This Technique

Background and Objectives: Intra-corporeal esophagojejunostomy after totally laparoscopic total gastrectomy (TLTG) remains one of the most technically demanding steps of minimally invasive gastric surgery. The management of the common entry hole in linear stapler-based reconstruc...

EFFECT OF Organisational CULTURE ON EMPLOYEE PERFORMANCE IN HEALTHCARE INSTITUTIONS: A Structured Literature Review with Implications for David Umahi Federal University Teaching Hospital (DUFUTH)

Organisational culture shapes how employees interpret institutional expectations, interact with colleagues, respond to leadership, share knowledge and perform assigned responsibilities. This review synthesises the literature compiled in the source manuscript on the relationship b...

EFFECT OF Organisational CULTURE ON EMPLOYEE PERFORMANCE IN HEALTHCARE INSTITUTIONS: A Structured Literature Review with Implications for David Umahi Federal University Teaching Hospital (DUFUTH)

Organisational culture shapes how employees interpret institutional expectations, interact with colleagues, respond to leadership, share knowledge and perform assigned responsibilities. This review synthesises the literature compiled in the source manuscript on the relationship b...

Fine-needle–based localization techniques in parathyroid adenomas: a retrospective cohort study of histopathological safety and fibrosis patterns

Abstract Background This study aimed to evaluate the association between fine-needle-based interventions widely used for preoperative and intraoperative localization of parathyroid adenomas and the development of post-excision stromal fibrosis and other histopathological changes...

Investigation of the relationship between breastfeeding myths and breastfeeding adaptation: a correlational survey study

The early postpartum period is a critical time frame in which mothers’ adaptation to breastfeeding is shaped and breastfeeding-related beliefs become evident. The aim of this study was to examine the relationship between the level of belief in breastfeeding myths and breastfeedin...

Regular AREDS2 Supplement Use in Age-Related Macular Degeneration: Factors Associated with Supplementation, Medication Adherence, and Patient-Reported Barriers

Background/Objectives: Age-related macular degeneration (AMD) is a leading cause of irreversible visual impairment, and AREDS2-based nutritional supplementation is recommended for clinically eligible patients to reduce the risk of disease progression. However, successful implemen...

Shoulder MRI for Forensic Age Estimation: Ossification Staging of the Proximal Humeral Epiphysis

Background/Objectives: Magnetic resonance imaging (MRI) of the proximal humeral epiphysis offers a radiation-free alternative for forensic age estimation in living individuals. This study aimed to characterize the relationship between chronological age and epiphyseal maturation u...

The effect of pulmonary nodule presence on disease severity and course in ANCA-associated vasculitis: a multicenter cohort study

Pulmonary nodules are common in ANCA-associated vasculitis (AAV), but their clinical relevance remains unclear. This study assessed the influence of pulmonary nodules and radiological features on clinical characteristics and outcomes in AAV. In this multicenter retrospective coho...

The Mediating Effect of Risk Awareness on the Relationship Between Infectious Disease Knowledge and Protective Behaviors Among Earthquake-Affected Populations

Background: Long-term post-disaster settings increase infectious disease risks, requiring adequate knowledge and risk awareness to promote protective behaviors. This study was conducted to investigate the relationships between infectious disease knowledge, risk awareness, and pro...

Small airway dysfunction and associated clinical characteristics in severe asthma under omalizumab and mepolizumab treatment.

BACKGROUND: Small airway dysfunction (SAD) plays a critical role in the pathophysiology of asthma. OBJECTIVE: This study aimed to evaluate the frequency of SAD in patients with severe asthma, and to assess its association with asthma control. METHODS: A total of 84 severe asthma...

Disease stage at diagnosis determines survival among Syrian refugee cancer patients treated at a metropolitan tertiary center in Türkiye

Refugee populations experience major challenges in accessing cancer diagnosis and treatment, which frequently leads to delayed presentation and more advanced disease stages. However, there is still limited information on survival outcomes of refugee cancer patients receiving care...

Association between the 2026 IDF-DAR risk category and Ramadan fasting intention among adults with diabetes in primary care: a cross-sectional study

Abstract Background The 2026 International Diabetes Federation–Diabetes and Ramadan (IDF-DAR) Risk Calculator supports Ramadan-related diabetes risk assessment, but its association with fasting intention in primary care is unclear. We examined the association between risk categor...

Evaluation of Alexithymia Level in Children With Cystic Fibrosis

The present study sought to determine the extent of alexithymia within the cystic fibrosis (CF) population and examine how it relates to both the severity of the illness and the effectiveness of patient disease management strategies. The study sample included adolescents aged 14...

Does the mother’s cooking skills influence the school-aged child’s adherence to the Mediterranean diet in Turkiye? a cross-sectional study

This cross-sectional descriptive study was designed and conducted to assess the effect of mothers’ cooking skills on school-aged children’s adherence to the Mediterranean diet. The demographic characteristics and anthropometric measurements of 388 mothers and children were collec...