University of Health Sciences Antigua

Association of Monocyte Subsets with Carotid Artery Stenosis Severity

Background and Objectives: This study aimed to investigate the association between circulating monocyte subset profiles and carotid artery stenosis (CAS) severity and to examine their relationships with inflammatory and atherosclerosis-related parameters. Materials and Methods: T...

Serum CXCL-10 and CTLA-4 levels in treatment-naive chronic hepatitis B: associations with EASL-based clinical phenotypes, histological inflammatory activity, and non-invasive fibrosis indices

Chronic hepatitis B (CHB) is a major global health issue, as ongoing viral replication can drive hepatic inflammation and immune dysregulation, increasing the risk of cirrhosis and hepatocellular carcinoma. CXCL-10, a proinflammatory chemokine, and CTLA-4, an inhibitory immune ch...

Muscle Dysmorphia and the Use of Nutritional Ergogenic Supplements Among Amateur Male Bodybuilders: A Cross‐Sectional Study

BACKGROUND: This study aimed to evaluate the levels of muscle appearance satisfaction and ergogenic aid use among adult male amateur bodybuilders. METHODS: In this descriptive cross-sectional study, a questionnaire containing demographic information, the "Nutrition Ergogenic Supp...

Artificial intelligence in eating disorder research: a scoping review with bibliometric analysis of trends, methodologies, and translational readiness (2016–2025)

Abstract Purpose Artificial intelligence (AI) applications in eating disorder research have expanded rapidly, yet the structure, scope, and translational readiness of this literature have not been systematically mapped. This study aimed to characterise publication trends, AI meth...

Comparative Efficacy of Modified Single-Patch versus Double-Patch Techniques in Atrioventricular Septal Defect Repair

Aim: This study aims to compare the early- and mid-term outcomes of modified single-patch and double-patch techniques for complete atrioventricular septal defect (AVSD) repair. We hypothesized that the modified single-patch technique offers similar or superior efficacy while redu...

Clinical Utility of the Atherogenic Plasma Index for Identifying Atherogenic Dyslipidemia: A Large Cross-Sectional Analysis Stratified by Sex and Thyroid Status

Background: The atherogenic plasma index (AIP) has emerged as a promising marker reflecting the balance between triglyceride (TG)-rich lipoproteins and high-density lipoprotein cholesterol (HDL-C). However, its clinical utility in identifying atherogenic dyslipidemia (AD), partic...

Association Between Nasal Septal Deviation Types and Eustachian Tube Function: A Prospective Observational Study

OBJECTIVE: This study aimed to objectively and subjectively evaluate the effect of nasal septal deviation (NSD) types, classified according to the Baumann system, on Eustachian tube function. METHODS: A total of 107 NSD patients (78 males, 29 females; mean age: 35.39 ± 9.55 years...

How appropriate are ChatGPT-5’s answers to acne questions?

Online conversational tools have become increasingly common sources of health information, with many patients seeking acne advice through such platforms. Although they may enhance awareness and encourage early consultation, their medical reliability remains uncertain. Because acn...

Beyond corneal structure in Noonan syndrome: topographic, tomographic, and optical findings

Introduction This study aimed to evaluate corneal topographic, tomographic, and wavefront characteristics in individuals with Noonan syndrome (NS) and to compare these findings with those of healthy controls.Methods This prospective, case–control study included 18 patients with N...

Exploratory Analysis of the C-Reactive Protein–Albumin–Lymphocyte Index and Progression-Free Survival in Early-Stage Classical Hodgkin Lymphoma

An easily accessible biomarker to predict early relapse in early-stage classical Hodgkin lymphoma (cHL) remains an unmet clinical need, and this study explored whether the C-reactive protein–albumin–lymphocyte (CALLY) index provides prognostic information in this setting. Ninety-...

Skeletal Distortion Manipulation in 2D–3D-Fused Boron Clusters Enables Solid-State Luminescence and Photothermal Conversion

Abstract Luminescent π-conjugated materials are central to modern optoelectronics, yet they are typically constructed from planar, rigid molecular frameworks. Herein, we introduce a conceptually distinct luminescent molecular platform based on three-dimensional (3D) boron cluster...

Structural and Optical Corneal Alterations in Inactive Herpetic Keratitis: A Quantitative Tomographic Analysis

Purpose To quantitatively characterize the structural and optical changes in the cornea in inactive herpetic keratitis and, secondarily, to evaluate whether these parameters vary according to lesion location and depth of vascularization.Methods This prospective cross-sectional st...

Microbiological monitoring of scuba cylinders under routine filling and seasonal diving conditions

Introduction: The aim of this study was to monitor the microbiological status of the inner surfaces of scuba cylinders under routine air filling conditions and to assess whether microbiological contamination emerges or persists over time. Methods: A prospective longitudinal micro...

Psychological Well-Being, Dispositional Hope, and Contentment with Life Among Public Hospital Physicians in Türkiye’s Black Sea Region: A Cross-Sectional Study

Background: Physicians work under demanding conditions that may affect their psychological functioning and evaluations of life. Positive psychological resources, particularly dispositional hope, may be relevant to the association between psychological well-being and contentment w...

From Metabolism to Molecular Phenotype: Carbonic Anhydrase IX–Targeted [ 68 Ga]Ga-DPI-4452 PET/CT in Renal Cell Carcinoma: A Prospective Multicenter Comparison with [ 18 F]FDG PET/CT

The objective of this study was to prospectively compare the diagnostic performance, lesion detection capability, and clinical staging impact of [68Ga]Ga-DPI-4452 PET/CT with that of [18F]FDG PET/CT in renal cell carcinoma (RCC) using a multicenter design. Methods: Sixty-eight pa...

Investigation of functional independence and developmental areas in preschool children with quadriplegic cerebral palsy and cortical visual impairment

Cerebral palsy (CP) is a neurodevelopmental condition that affects areas of development and functional independence. Cortical Visual Impairment (CVI) is an important problem frequently observed in children with CP. This study was planned to compare the functional independence and...

Age-associated medialization of the cervical internal carotid artery: CT morphometric findings and an exploratory combined mucosa–midline grading framework

Purpose Cervical internal carotid artery (ICA) medialization may narrow anatomical safety margins during transoral and pharyngeal procedures. We quantified age-associated ICA morphometric changes on computed tomography (CT), assessed age-based discrimination for study-defined cri...

Development of a Plant Bioactive-Rich Tahini-Based Powder Enriched with Pea Protein and Coconut Milk Powder: Antioxidant Properties, Nutritional Characterization, In Vitro INFOGEST Static Digestion

This study aimed to develop a spray-dried tahini-based powder enriched with pea protein and coconut milk powder and to comprehensively characterize its plant bioactive composition, antioxidant potential, nutritional properties, and bioaccessibility following the standardized INFO...

Emerging cfDNA technologies in glioblastoma through fragmentomics and sonobiopsy

Glioblastoma (GBM) is difficult to monitor using liquid biopsy because the tumor-derived fraction of circulating cell-free DNA (cfDNA), i.e., circulating tumor DNA (ctDNA), is often very low in plasma and because spatial and temporal heterogeneity complicate single-variant tracki...

Genotype–cognitive phenotype associations in Duchenne muscular dystrophy: the role of mutation location and ambulatory status in a pediatric cohort

Duchenne muscular dystrophy (DMD) is characterized by progressive motor decline as well as cognitive impairment and reduced quality of life. This study aimed to investigate the relationship between genotype, cognitive functioning, and quality of life in children with DMD. This cr...