University of Geneva

An information-theoretic proof of the Planckian bound for thermalization

Abstract It has been conjectured that the speed of thermalization is universally constrained by a Planckian timescale, τ Pl = ℏ /( k B T ), determined solely by the reduced Planck constant ℏ, Boltzmann’s constant ( k B ) and the temperature ( T ). However, a general and model-ind...

Internal resources and the decision to engage in wine tourism: a supply-side analysis of Spanish wineries

Purpose This study adopts a supply-side perspective to examine the associations between firm-level characteristics, territorial factors and the decision to engage in wine tourism. Design/methodology/approach Using a multisource data set from 688 Spanish wineries, the authors use...

The bi-functional for the non-additive kinetic potential at dissociation

The eigenvalue equations defined in frozen-density embedding theory (FDET) [T. A. Wesołowski, Phys. Rev. A 77, 012504 (2008)] feature the non-additive kinetic potential given as a bi-functional, depending on a pair of electron densities (vtnad[ρNA,ρNB]). In computational methods...

High-salt diet modulates endocrine regulation between cortisol and FGF23

Excessive dietary salt intake is a global health concern, affecting cardiovascular, renal, and bone health. While the renin-angiotensin-aldosterone system (RAAS) is a known regulator of dietary salt-induced hormonal responses, the impact of adrenal cortisol remains unclear. Here,...

Transgenerational inheritance of altered H3K27me3 in wild-type Caenorhabditis elegans

Abstract Epigenetic inheritance provides mutation-free mechanisms for phenotypic adaptation, including modifications to DNA or DNA-associated proteins that create patterns of heritable gene regulation. However, the limits and regulation of this inheritance remain incompletely und...

On quivers, spectral networks and black holes

Abstract It was recently found that connection coefficients of the Heun equation can be derived in a closed form using crossing symmetry in two-dimensional Liouville theory via the Nekrasov–Shatashvili functions. In this work, we systematize this approach to second-order linear O...

Balanced contractility and adhesion drive polarization in a minimal elastic actomyosin network

Polarization of migrating cells involves chemical and mechanical interactions of signaling networks, cytoskeleton, plasma membrane, and substrate adhesions. Still, it is not fully understood which mechanisms and components are sufficient for symmetry breaking, and if they work in...

Beyond techno-economic assessments: A comparative political economy framework for assessing national carbon dioxide removal (CDR) deployment

Carbon dioxide removal (CDR) has become a contested yet critical component of net-zero strategies despite its deployment consistently lagging corporate and government ambitions. This article develops and applies a comparative political economy framework to assess national CDR dep...

Proximity biotinylation at the host-Shigella interface reveals UFMylation as an antibacterial pathway

Abstract Host cells contest invasion by intracellular bacterial pathogens with multiple strategies that recognise and/or damage the bacterial surface. To identify host defence factors targeted to intracellular bacteria, we developed a proximity biotinylation approach coupled to q...

The labour of academic translation

Abstract This article explores the potential of Porter’s (1985) seminal value chain model as a new tool for the industry turn in Translation Studies. The model seeks to identify which of a business’s various functions generate the most surplus value and thereby build competitive...

Knowledge-enhanced LLMs for multilingual biomedical concept normalization: a multilingual benchmarking and behavioral analysis

Abstract Biomedical concept normalization (BCN)—mapping clinical terms to standardized concepts in biomedical terminologies—is a key bottleneck for semantic interoperability across health information systems, particularly in multilingual settings and when terms appear with minima...

Biodegradability test on a corn starch based compostable plastic bag: impact of moisture on CO2 emissions, microbial communities, and enzymatic activities

Compostable plastics are often considered as a solution for minimizing plastic contamination due to their biodegradation capacity in composting processes. However, the standards evaluating their biodegradability do not encompass the variability of uncontrolled composting systems,...

What is in a word? Discourse and practice of international security in a new world

Abstract The world order is undergoing significant changes, marked by growing contestation of the liberal international order (LIO). This article examines how these shifts are reflected in the way international security is conceptualised. It analyses changes in security conceptua...

Ionophore-Based Voltammetric Ion Transfer Microscopy: Imaging Enzyme-Generated Ammonium in Flow

Abstract Spatially resolved measurements of ion concentration gradients provide valuable insight into chemical, biological, and environmental processes. Recently, Voltammetric Ion Transfer Microscopy (VITM) was introduced as a novel opto-electrochemical imaging technique capable...

Spark-Engineered Microelectrode Arrays from Disposable Screen-Printed Macroelectrodes

Abstract A computer numerical control (CNC)-guided spark-assisted localized microelectrode patterning is used for the first time for the programmable fabrication of electrodes exhibiting microelectrode behavior with high spatial precision. A graphite wire serves as a spark probe...

Small-world organization as a representation-dependent signature of nonlinear dynamics in biological time series

Abstract Small-world topology is usually interpreted in connectivity networks, but graphs derived from individual time series have different node and edge semantics. We examined how three common time-series representations—Quantile Graphs (QG), Gramian Angular Fields (GAF), and M...

Integrating Next-Generation Reproductive Organoids with Genomics, Multi-Omics and Bioengineering to Understand Human Infertility

Infertility affects approximately one in six individuals worldwide and is a highly heterogeneous disorder resulting from the complex interplay of genetic, epigenetic, endocrine, environmental and lifestyle factors. Although numerous genes and molecular pathways involved in female...

Anatomy of the simplest renormalon

Perhaps the simplest IR renormalon occurs in the ground state energy of a superrenormalizable model, the scalar O(N) O ( N ) theory in two dimensions with a quartic potential and negative squared mass. We show that this renormalon, found previously in perturbation theory at next-...

Musical Chemistry and Spectroscopy: Analogies Bridging Two Worlds in Multiple Dimensions

ABSTRACT Music and chemistry are seldom mentioned in the same breath, yet the physical and mathematical principles underpinning both disciplines are deeply intertwined. Here, we explore several points of contact between the two fields, centered on their shared language of frequen...

Single‐cell RNA sequencing of peripheral blood defines two immunological subtypes of Sjögren's disease distinguished by anti‐SSA antibodies and aberrant B cell populations

OBJECTIVES: Sjögren's disease (SjD) is a heterogeneous autoimmune disorder characterized by substantial clinical and molecular diversity. This heterogeneity raises key questions regarding the existence of distinct pathogenic mechanisms underlying disease subtypes. The objective o...