Université de Montpellier

First-Principles Simulation of Ionizing Radiation Damage in Molecular Systems over Short Time Scales

Abstract In this work, we present an ab initio molecular simulation method designed to investigate the ultrashort time scales of radiation chemistry induced by ionizing radiation, in particular fast ions and electric pulses. The approach accounts for energy deposition at the subf...

Collective adsorption of pheromones at the water–air interface

Abstract Understanding the phase behaviour of pheromones and other messaging molecules remains a significant and largely unexplored challenge, even though it plays a central role in chemical communication. Here, we present all-atom molecular dynamics simulations to investigate th...

Protocol for integrative transcriptomic/metabolomic analysis: A case study on factors influencing the oyster-POMS disease

Deciphering the molecular mechanisms underlying complex biological interactions requires comprehensive approaches that capture these interactions across multiple regulatory and functional levels. Here, we present a protocol applied to the host-pathogen-environment interactions un...

Wild-type and mutated ß-catenin differently repress RND3/RHOE expression in hepatocellular carcinoma

Tumor development and progression are mainly driven by oncogenic mutations but are also regulated by physical factors. Through its structural and transcriptional functions, ß-catenin is a key factor that acts on both aspects to promote liver tumorigenesis, leading to hepatocellul...

Assessing plant area index and 3D plant area distribution in wheat canopies from a terrestrial LiDAR system for high-throughput plant phenotyping

This study investigates a new methodology to estimate plant area index ( PAI ) and its spatial distribution from 3D point clouds acquired by a system of 3 LiDARs (2 nadir-viewing and one at 45°) mounted on the Phenomobile Unmanned Ground Vehicle designed for high-throughput pheno...

Accelerating Identification of Relevant Polarons in Batteries

Abstract Many of the materials under consideration as battery electrodes are known to exhibit polarons─charge carriers localized through polarizing their environments, which are unfortunately quite costly to tackle by theory. Next to costly ab initio methods and geometry optimiza...

The WoKaS-Iso database: workflow for a global compilation of oxygen-18 and deuterium records in karst springs and cave drip water for enhanced understanding of karst systems

For analysing karst hydrogeological systems, observations of karst springs and cave drips are considered indispensable. In addition to hydrometric observations, knowing the oxygen and hydrogen stable isotope ratios has improved the understanding of vadose zone and aquifer dynamic...

Adolescent elite swimmers’ self-esteem and emotional states: Benefits of organized leisure-time activities

This study examined whether an Organized Leisure-Time Activities program (OLT3A) strengthens self-esteem and emotional states in elite adolescent swimmers. Twenty-five national-level swimmers (Mage = 14.44 ± 1.23 y) were randomized to a six-week OLT3A intervention or a waiting-li...

Indoor UAV for Nuclear Investigation: Experimental Qualification and Field Feedback

ABSTRACT Indoor Unmanned Aerial Vehicles (UAVs) have recently gained interest for inspection and investigation tasks in hazardous environments. In the nuclear field, indoor UAVs offer promising capabilities to reduce workers' exposure to ionizing radiation while accessing confine...

Immune‐related adverse events with mogamulizumab in cutaneous T‐cell lymphoma: A multicentre study

BACKGROUND: Mogamulizumab, an anti-CCR4 monoclonal antibody used in advanced mycosis fungoides (MF) and Sezary syndrome (SS), also depletes regulatory T cells, potentially leading to immune-related adverse events (irAEs). Unlike mogamulizumab-associated rash (MAR), other irAEs re...

Representation-Aware Reasoning: From Representational Vigilance to Candidate Re-Representations

Representation-Aware Reasoning (RAR) addresses a conditional methodological problem: once an active representation becomes an explicit object of scrutiny, how should alternative representations be formulated and compared without turning an anomaly into an automatic requirement fo...

Stem-cell modeling of cerebellar dysfunction of Angelman syndrome

Angelman syndrome is a severe neurodevelopmental disorder caused by loss of function of the maternal allele of the neuron-specific imprinted gene UBE3A. Although Angelman syndrome presents with developmental delay, ataxia, epilepsy, and speech impairment, the contribution of spec...

Serum GFAP and Age Accurately Distinguish AQP4 ‐ IgG Positive and Double Seronegative NMOSD From MOGAD After a Recent Attack

BACKGROUND: Serum neurofilament-light chain (sNfL) and glial fibrillary acidic protein (sGFAP) are associated with multiple sclerosis (MS) activity. This study aimed to identify patient- and disease-level determinants of sNfL and sGFAP and to evaluate their ability to support dif...

Early insights into predicted efficacy of Ebola monoclonal antibodies for the 2026 Bundibugyo virus disease outbreak

The 2026 Bundibugyo virus disease (BVD) outbreak in the DRC and Uganda raises urgent questions about the efficacy of existing Ebola virus (EBOV) monoclonal antibodies (mAbs) against Bundibugyo virus (BDBV). Here, we perform genomic and structural analyses of 44 BDBV sequences, in...

Strengthening Collective Professional Engagement around COPD: An Action Research in Primary Care

International audience

Rotation groups, mediangle graphs, and periagroups: A unified point of view on Coxeter groups and graph products of groups

In this article, we introduce rotation groups as a common generalisation of Coxeter groups and graph products of groups. We characterise these groups algebraically by presentations ( periagroups ), and we propose a combinatorial geometry ( mediangle graphs ) to study them. As an...

Post-disturbance temperate reef states influence fish contributions to nature and people

Abstract Background Climate-driven habitat reorganization is reshaping the capacity of marine ecosystems to sustain biodiversity and human well-being, with implications for SDG 14 (Life Below Water) and SDG 2 (Zero Hunger). Yet, it remains unclear to what extent post-disturbance...

A refined Saccharomyces cerevisiae reference transcriptome from Direct RNA Sequencing, with a reusable pipeline for UTR annotation updates

Untranslated regions (UTRs) flanking the coding sequence govern mRNA translation, localisation, and decay, making accurate UTR boundaries essential for quantitative RNA sequencing and the study of post-transcriptional control. Reference transcriptomes built from short-read sequen...

The elongation of Mest transcript into MestXL sustains, but does not initiate, the maternal allele bias of its convergent gene Copg2 during neurogenesis

Abstract Precise gene dosage control is critical for cellular identity and development, particularly for imprinted genes, where dosage imbalances are linked to neurodevelopmental disorders. The Mest/Copg2 imprinted locus exemplifies this fine-tuned regulation: while Mest is const...

Sterile Insect Technique in a n-patch System with Allee Effect and Mass Trapping: Modelling, Analysis and Simulations

Abstract The sterile insect technique (SIT) is a biological control method aimed at reducing or eliminating populations of pests and disease vectors. This technique involves releasing sterilised insects which, by mating with wild individuals, will reduce the target population. In...