Université de Montpellier

Uncovering Newcastle disease virus dynamics in Northern Nigeria: insights from an epidemiological survey in unvaccinated village poultry

Abstract Background Newcastle disease virus (NDV) remains a major constraint to village and backyard poultry production in Nigeria, where limited vaccination and low biosecurity may facilitate sustained virus circulation. This study investigated the serological and molecular epid...

Anticancer and Cardioprotective Properties of Medicinal Mushrooms: Current Evidence and Future Prospects

Introduction: Cardiotoxicity is an undesirable side effect of chemotherapy that limits the effectiveness of cancer treatment. Almost all cardiotoxic agents cause cardiovascular complications, leading to oxidative stress and other pathological conditions. The search for bioactive...

Coffea Comparative Genomics Reveals Subgenome-Associated Expansion and Diversification of Biosynthetic Gene Clusters

Biosynthetic gene clusters (BGCs) are important for plant specialized metabolism, but remain poorly characterized in coffee. Given Brazil’s importance in coffee production, we performed a comparative genomic analysis of BGCs across the allotetraploid Coffea arabica and its diploi...

Forgotten reservoirs: an attempt to revive field research on rodent malaria parasites in their main natural host, the thicket rat Grammomys poensis (formerly Thamnomys rutilans)

<title>Abstract</title> Rodent malaria parasites have long served as essential experimental models for understanding human malaria, yet little is known about their ecology and evolution in the wild. The thicket rat <italic>Grammomys poensis</italic> (formerly <italic>Thamnomys ru...

Conformal Assembly of Platinum on Self-Standing Structured Cathodes for PEMFCs

Abstract A self-standing cathode architecture for proton exchange membrane fuel cells was developed. A conformal, thin layer of platinum was electrodeposited on a self-standing carbon-fiber-based structured support in the form of an extended-surface particulate film. Abundant gra...

Autoantibodies neutralizing type I interferons underlie a third of cases of Chikungunya virus encephalitis or myelitis

Abstract Chikungunya virus (CHIKV) infection is typically not life-threatening but may, in rare cases, affect the central nervous system (CNS). In three cohorts of confirmed CHIKV cases from Martinique (French overseas territory) and Brazil (patients aged 0–89 years, n = 245), 20...

Genetic variability and population structure within the Anopheles tessellatus complex (Theobald, 1901) in Indonesia using ITS2 nuclear and COI, COII mitochondrial sequences

Abstract Some Anopheles species that act as malaria vectors are members of species complexes, a concept whereby sibling species cannot be differentiated solely on the basis of morphological characters. Therefore, species complexes represent a major problem in malaria vector contr...

Electrospun Nanofibers Loaded with Verbena officinalis Extract as Multifunctional Bioactive Wound Dressings

Background/Objectives: Verbena officinalis has long been used in traditional medicine for treating skin disorders, yet its potential in advanced wound-dressing systems remains insufficiently explored. This study aimed to characterize V. officinalis extracts obtained using differe...

Glycosphingolipids are essential entry factors for non-influenza orthomyxoviruses

Thogotoviruses and quaranjaviruses are arthropod-borne orthomyxoviruses that circulate widely in wildlife and domestic animals and include several zoonotic members. Despite their close phylogenetic relationship to influenza viruses, the mechanisms underlying their replication rem...

Mechanistic Investigationof Visible-Light-DrivenPhotocatalysis in Bio-Synthesized Graphitic Carbon Nitride/MgO NanocompositesToward Safranine Orange Dye

Abstract In this work, we report a sustainable strategy for the synthesis of magnesium oxide (MgO) nanoparticles, graphitic carbon nitride (g-C3N4), and MgO/g-C3N4 nanocomposites derived from orange peel waste, with MgO loadings ranging from 28 to 76 wt %. Comprehensive physicoch...

Genetic distance and pollinator sharing shape divergence in floral volatiles in closely related dioecious Ficus species

Abstract Premise Floral scent is central to host recognition in the fig–fig wasp mutualism, yet how scent divergence relates to pollinator sharing among closely related dioecious Ficus species remains unclear. Methods We analyzed volatile organic compounds (VOCs) from four pairs...

Sequence‐encoded determinants drive distinct early aggregation pathways and different structural outcomes in PNT1 fibrils across Henipavirus members

Protein aggregation is increasingly recognized as a biologically relevant process in viral proteins, yet the molecular determinants governing such phenomena remain poorly understood. Intrinsically disordered proteins (IDPs) are ubiquitous in viral proteomes, where conformational...

Beyond IPCC’s narratives on livestock: the need for integrated and holistic metrics

The early IPCC assessment reports (2001, 2007) predominantly conceptualised livestock in technical and efficiency-oriented terms, focusing on productivity and technological innovations, while the 2014 and 2022 reports embed livestock within broader socio-environmental frameworks,...

Imaging in France: 2026 Update

France has seen significant advancements in radiology in recent years, driven by innovations in research and clinical practice. French groups have developed innovative imaging techniques and artificial intelligence applications in the field of diagnostic imaging and interventiona...

Awake craniotomy for drug-resistant non-oncological epilepsy: a systematic review of feasibility, reported safety, and seizure outcomes

Abstract Introduction Complete resection of the epileptogenic zone offers the best chance of seizure control in patients with drug-resistant epilepsy. However, surgical management remains challenging when the epileptogenic zone is located within or adjacent to eloquent brain regi...

Characterising recent antimalarial resistance in West Africa: Insights from amplicon sequencing of 17,384 Plasmodium falciparum infection samples

<ns5:p> Background <ns5:italic>Plasmodium falciparum</ns5:italic> ( <ns5:italic>P. falciparum</ns5:italic> ) infection remains a significant public health threat in West Africa, where chemoprevention and first-line therapies are key interventions against malaria. However, the dev...

Prevalence and phenotypic profiles of ESBL-producing Escherichia coli across the human-animal-environment interface: a One-Health surveillance during the first year of implementation of the Tricycle project in Burkina Faso

Antimicrobial resistance (AMR) is a major global health threat. The WHO Tricycle protocol applies a “One Health” approach to monitor extended-spectrum beta-lactamase-producing Escherichia coli (ESBL-Ec) in humans, animals, and the environment. This study was aimed at presenting t...

An N-terminal CDC42 T43I variant reveals the mechanism of pyrin inflammasome activation

Heterozygous carboxyl-terminal variants in the RHO guanosine triphosphatase (GTPase) CDC42 are known to cause severe autoinflammatory syndromes. Here, we identified a heterozygous amino-terminal p.T43I (Thr 43 →Ile) CDC42 variant in patients with autoinflammation and uncovered a...

Dietary behaviour of Sepedon (Parasepedon) ruficeps and Sepedon (Sepedomyia) nasuta (Diptera: Sciomyzidae) and the distribution of their snail prey in Benin (West Africa)

Sciomyzidae (Diptera) larvae live as predators and/or parasitoids of snails. They have potential economic importance as biological control agents against gastropods that are vectors of parasitic diseases. In the present study, the use of Sepedon larvae in schistosomiasis control...

STABILOOP, a cohort trial to assess automated insulin delivery in the management of patients living with type 1 diabetes who are eligible for islet transplantation

A limited subset of people living with type 1 diabetes (T1D) is affected by extreme glycemic lability and frequent unpredictable severe hypoglycemia, significantly impairing quality of life and associated with higher morbidity, mortality, and healthcare costs. Islet transplantati...