Institution
Universidade Federal de Minas Gerais
Recent research
- Society & EconomicsOpen access
Evolutionary biophysics in Brazil
Abstract Physicists have been fascinated by the biological sciences for many years, but it has also deemed not amenable to be studied by the molecular sciences—for most of recorded history it was actually believed that biology had its own laws, a view that started to erode when t...
- Health & MedicineOpen access
Latin America has become a major source of conceptual and evidence-informed policy innovation in response to the expansion of ultra-processed foods (UPFs).1–3 Although much of this processing-based policy architecture emerged through public health and food and nutrition security...
- Health & MedicineOpen access
Background/Objectives: Interethnic variability significantly influences drug response, highlighting the importance of assessing genomic ancestry for personalized medicine. Although Latin American populations are highly admixed, they remain underrepresented in pharmacogenetic rese...
- AI & ComputingOpen access
Best Practices Guide for Ecological Data Curation and Management
Data curation and management are essential for maintaining the integrity, longevity, and usability of information generated by environmental monitoring programs, particularly those involving multiple teams, sampling events, and longitudinal timeframes. Historically, the absence o...
- Biology
Yeasts recovered from wastewater of a public hospital in Minas Gerais state, Brazil, included a single isolate representing a putative novel species. Sequence analysis of the ITS-5.8S region and the D1/D2 domains of the LSU rRNA gene placed this yeast within the genus Sungouiella...
- BiologyOpen access
Abstract Satellite DNAs (satDNAs) are non-coding tandem repeats that can comprise more than 20% of eukaryotic genomes. They contribute to structural and regulatory processes in the genome and often evolve rapidly, shaping early stages of genetic differentiation between population...
- Engineering & TechnologyOpen access
Abstract : Conventional ion-exchange and chelating resins are widely used for metal recovery, purification, and polishing, yet they are still frequently compared using equilibrium capacity rather than process function. This structured critical review examines how charge-driven ex...
- Biology
Cognitive Effort as a Compensatory Mechanism for Motor Control in Impulsivity
Impulsivity, although commonly associated with maladaptive behavior, can influence how individuals manage cognitive and motor demands. This study analyzed the effect of impulsivity on motor control and cognitive effort during manual aiming tasks that varied in cognitive load. Fro...
- Health & MedicineOpen access
Study Design Retrospective-prospective multicenter comparative cohort study. Objectives Postoperative dysesthesia (POD) is a recognized complication of transforaminal endoscopic lumbar surgery, with reported rates up to 21.5%. Degenerative lumbar deformity may amplify this risk t...
- AI & ComputingOpen access
The Base-Point Barrier: Certifying Low-Rank Truncation Costs a Full Evaluation Pass
Deciding what a low-rank truncation costs in accuracy requires evaluating the truncated network, and this paper proves that nothing measured where the network already sits can take the place of that evaluation. Eckart–Young–Mirsky bounds reconstruction error, not accuracy, and th...
- AI & ComputingOpen access
Two decisions made before a network is compressed are usually treated as settled by uncompressed performance: which activation function to use, and whether to compress after training or to train under the rank constraint from the start. We show that both decisions reverse under a...
- AI & ComputingOpen access
Knowing When Retrieval Has Failed: A Cheap, Unsupervised Signal That Generalizes Across Domains
Retrieval-augmented generation fails silently: when the retriever returns irrelevant passages, the language model answers anyway, and in high-stakes domains such as mental health question answering a fluent answer built on bad context can be harmful. For anyone running RAG who ne...
- Health & MedicineOpen access
Abstract The supramolecular interactions between selegiline hydrochloride (SEL) and β-cyclodextrin (βCD) derivatives were investigated through isothermal titration calorimetry (ITC), nuclear magnetic resonance (NMR), and molecular dynamics (MD) simulations. Thermodynamic analyses...
- AI & ComputingOpen access
Two decisions made before a network is compressed are usually treated as settled by uncompressed performance: which activation function to use, and whether to compress after training or to train under the rank constraint from the start. We show that both decisions reverse under a...
- AI & ComputingOpen access
The Base-Point Barrier: Certifying Low-Rank Truncation Costs a Full Evaluation Pass
Deciding what a low-rank truncation costs in accuracy requires evaluating the truncated network, and this paper proves that nothing measured where the network already sits can take the place of that evaluation. Eckart–Young–Mirsky bounds reconstruction error, not accuracy, and th...
- Climate & EnvironmentOpen access
Abstract We report the oldest record of a capybara (Caviidae: Hydrochoerinae) in Chile, dated at ca. 8.8 Ma, which along with paleobotanical proxy records, indicates a markedly wetter late Miocene Atacama Desert. Today hyperarid, the Atacama contrasts sharply with the semiaquatic...
- BiologyOpen access
COCaDA-web: an interactive web server for exploratory analysis of interatomic contacts in proteins
Protein contacts often serve as prerequisites for characterizing molecular interactions and bonds. Traditional implementations remain computationally expensive, posing significant scalability and usability challenges. We present COCaDA-web, an interactive and user-friendly Web Se...
- Engineering & TechnologyOpen access
This study introduces an optimal control framework for functional electrical stimulation (FES) cycling that produces personalized stimulation patterns directly transferable from simulation to experimental cycling, without the need for empirical tuning. We use a physiological musc...
- Health & MedicineOpen access
Antimicrobial peptides as computational candidates for SARS-CoV-2 papain-like protease inhibition
SARS-CoV-2 papain-like protease (PLpro) remains an attractive antiviral target because of its dual role in viral polyprotein processing and host immune modulation. In this study, we employed an exploratory structure-based computational workflow to identify antimicrobial peptide s...
- Biology
Background: Ileal pouch–anal anastomosis (IPAA) is the standard restorative procedure for patients with ulcerative colitis requiring colectomy. Although robotic-assisted surgery has gained increasing acceptance in colorectal surgery, its role in IPAA remains uncertain. Methods: A...