Universidad Nacional Autónoma de México

Systematic review and exploratory spatial analysis of bat trypanosomatid infections in Mexico

Abstract Introduction Trypanosoma spp. and Leishmania spp. are protozoan parasites of public health importance. Bats can act as hosts, but evidence from Mexico remains fragmented and has rarely been examined within a One Health spatial framework. The Maya Train and the Interocean...

Energetic insights into alendronate–β-cyclodextrin complexation

Abstract Bisphosphonates are widely used for the treatment of bone-related disorders; however, their low bioavailability limits therapeutic efficacy and increases long-term adverse effects. This study investigated the thermal behavior and binding energetics of the alendronate (AL...

GRB 260310A / SN 2026fgk: A Multi-Wavelength Study of a Nearby Underluminous Long GRB and SN with a Complex Afterglow

Abstract We present a comprehensive multi-wavelength study of GRB 260310A / SN 2026fgk, a nearby (z = 0.153), long-duration gamma-ray burst (GRB) with an exceptionally underluminous prompt γ-ray emission and a Comptonized spectrum. The burst occurred at the edge of a blue host ga...

Socioecological Trade-offs in the Yucatan Peninsula: Stakeholder Perceptions of How Urban and Tourism Development Reshape Nature’s Contributions to People

Tourism expansion and urban development in the Yucatan Peninsula have intensified pressures on ecosystems, altering the natural contributions to people (NCP) that sustain regional wellbeing. To better understand emerging socioecological conflicts, we applied a multi-criteria anal...

Finite Element Analysis of Stress Distribution in Healthy and Restored Mandibular Molars with Zirconia and Lithium Disilicate Crowns Under Vertical and Oblique Loading

The mechanical compatibility between dental restorative materials and the natural tooth structure is a relevant factor for long-term clinical performance. Although zirconia (yttria-stabilized tetragonal zirconia polycrystal, Y-TZP) and lithium disilicate are widely used for full-...

Ser715 PhosphorylationInduces β-HairpinUnfolding and Destabilization of FOXM1 Autoinhibition

Abstract FOXM1 is a cell proliferation-driving transcription factor activated by phosphorylation-induced conformational changes. In its inactive state, an intramolecular β-hairpin within the transactivation domain (TAD) binds the N-terminal repressor domain (NRD), forming a compo...

Local capacity building and policy evaluation in climate and environmental governance

Identifying challenges and opportunities to enable and accelerate urban transformational solutions is increasingly urgent, particularly as the world becomes more urbanized and approaches an environmental overshoot scenario. This paper focuses on the role of local capacities in cl...

Trace-element enrichment in agricultural soils under wastewater-influenced surface-water irrigation: a plot-scale study in an Andean micro-watershed

Abstract The use of wastewater-influenced surface waters for agricultural irrigation is common in many regions, yet its implications for soil geochemistry remain insufficiently characterized, particularly in Andean micro-watersheds. This study evaluates the occurrence and distrib...

Close relationship and role of fractal dimension, heterogeneous nucleation, dynamic transformations and cooperativity mechanisms in unperturbed tumor growth

<title>Abstract</title> The cancer is the second leading cause of death worldwide and remains an enigma for researchers and medical doctors. The aim of this study is to propose a novel methodology that demonstrates the close relationship and role of fractal dimension, heterogeneo...

Stereoselectivity inLiquid Aerosols through Acid-MediatedEpoxide Ring-Opening Reactions

Abstract Stereoisomers in aqueous atmospheric aerosols are assumed to be present in equal concentrations, as aerosols are most commonly mixtures of simple inorganic salts with a range of organic species that lack obvious pathways to induce stereoselectivity. Further, since submic...

A geometric algebra approach to coincidence site lattices

Abstract When a lattice in Rn is superimposed on a rotated copy with coincident origins, coincidence points may arise for specific rotations, forming a coincidence site lattice (CSL). In crystallography, particularly in two and three dimensions, CSL theory is fundamental for desc...

Thromboxane A2-Driven Vascular Hyperreactivity in Cadmium-Induced Hypertension: Role of Oxidative Stress and Therapeutic Implications

Background/Objectives: Environmental factors, including heavy metals such as cadmium, are increasingly recognized as important contributors to hypertension beyond traditional risk factors. To date, the role of angiotensin and alpha-adrenergic receptors in hypertension induced by...

Genomic catalogue of giant viruses reveals expanded diversity and functional potential

Nucleocytoplasmic large DNA and Mirusviricota viruses exhibit taxonomic richness which continually expands due to metagenomic sequencing. Here we curate a database of giant virus metagenome-assembled genomes (GVMAGs V2), comprising 8,508 species-level representatives from 18,727...

Curcumin Nanoemulsion: Characterization and Effect on Cataracts in an In Vivo Animal Model and Ex Vivo Human Model

Cataracts are the leading cause of reversible blindness worldwide; this condition results from the aggregation of lens proteins. Currently, surgery remains the only treatment; however, there is growing interest in non-surgical approaches, including the use of bioactive compounds...

Exohedral 1:2Complexes of Lanthanide Atoms with theC60 Fullerene: What Hapticity Is Preferred, η10, η11, or η12?

Abstract The structure of crystalline lanthanide–C60 fullerides allows for the Ln atom coordination to two rings of adjacent fullerene molecules simultaneously, where the resulting Ln hapticity can be η10, η11, or η12. We analyze the geometries, bonding strength, charge, spin, an...

An Agent-Based Model of the Stellar Mass Distribution

The Initial Mass Function (IMF) describes the distribution of stellar masses formed in a stellar cluster and constitutes a fundamental constraint for theories of star formation. In this work, we investigate the emergence of the IMF slope using a minimal agent-based model inspired...

Uneven progress in Alzheimer’s disease and other dementias across Mexico, 1990–2023: updated estimates from the Global Burden of Disease Study

Objectives To quantify the magnitude and trends the national and subnational burden of Alzheimer’s disease and other dementias (ADOD) in Mexico from 1990 to 2023, analyzing patterns by sex and age and exploring their association with the Socio-Demographic Index (SDI) and the Heal...

Association between risk of eating disorders and an unhealthy lifestyle score in university students: uniHcos project

Introduction The first year of university is a critical period for the consolidation of lifestyle habits and has been associated with an increased risk of developing eating disorders (EDs). This study aimed to assess the prevalence of ED risk among first-year Spanish university s...

Behavioural impact of microplastics on zebrafish development

Microplastic (MP) pollution in aquatic environments is ubiquitous and characterized by particles of highly irregular shapes. Yet, most laboratory studies examining MPs impacts on aquatic species rely on pristine polymer spheres, which poorly reflect the diversity and complexity o...

Enhanced Photolysisand Photocatalysis Assisted byHydrodynamic Cavitation for the Removal of Methylene Blue Dye

Abstract This study investigates the synergistic integration of hydrodynamic cavitation (HC) with photolysis and photocatalysis to enhance the degradation of synthetic dyes in aqueous systems. Methylene blue (MB) is selected as a model pollutant, and tap water is used as the work...