Universidad Nacional Autónoma de México

Poloxamer/HPMC/Carbopol-Based Thermosensitive Hydrogel Loaded with Ibuprofen for Potential Vaginal Drug Release

Vaginal drug delivery offers a critical route for local treatments but is limited by short formulation residence times. This study describes a thermosensitive in situ gel prepared by the cold-dissolution method from a ternary blend of Pluronic F127, Carbopol 940, and HPMC for loc...

Scientific Watchdog Journalism in Latin America: A Challenge of Broken Mirrors

The watchdog role of science journalism, as a way of revealing wrongdoings in science-driven enterprises, is a recent and rather invisible practice in Latin America. From my 20 years as a practitioner, this commentary explores some structural causes of this phenomenon: insufficie...

Leeuwenhoek in Mexico: new paths in the global circulation of scientific knowledge

Abstract Anthony van Leeuwenhoek (1632–1723) was the first to observe single-celled organisms. Between 1673 and 1723 he sent 189 letters containing scientific observations to the Royal Society, 114 of which were edited into 117 published articles in the Philosophical Transactions...

Full-spur mapping: refining coral reef carbonate production estimates using underwater photogrammetry

Abstract Traditional methods for estimating calcium carbonate production on coral reefs rely on in-water line transects that sample only a fraction of the reefscape, inherently introducing spatial biases and under-representing the heterogeneity of coral assemblages. Here, we diag...

Spatial co-occurrence of exotic species in an urban reserve in Mexico City

Exotic species can interact positively or negatively with other exotic species. The patches of original vegetation immersed within some urban centers may be vulnerable to invasion by exotic species, which may compromise the value of these urban ecological reserves for the conserv...

Atmospheric Dynamics and Diversity of Alternaria and Fusarium in a Common Wheat (Triticum aestivum L.) Crop in NW Spain

Abstract This study investigated the diversity of Alternaria and Fusarium species in atmospheric aerosols and plant tissue in a common wheat crop in NW Spain. The relationship between atmospheric fungal spore concentrations and weather conditions was analysed. To this end, non-vi...

Temporally structured motor and auditory representations in covert syllable production

Inner speaking—the deliberate generation of speech through covert production mechanisms—is a common human experience. Current accounts propose that it engages sensorimotor processes similar to those underlying overt speech. Here, we asked whether motor and auditory representation...

Impact of anthropogenic activities on the microplastic pollution status of an urbanized wetland

Due to their environmental ubiquity, persistence, and potential effects on living organisms, microplastic pollution has become a global concern. Urban wetlands, catchment basins within cities, are one of the final sinks of these pollutants. We studied the occurrence, abundance, d...

Charting Endocrine Progenitors Across Species and Organs

ABSTRACT Hormone‐producing cells in the pancreas and intestine regulate whole‐body metabolism and are dysregulated in obesity and diabetes. A deeper understanding of endocrine lineage formation (endocrinogenesis) in these organs is essential to elucidate the healthy state and dis...

Seasonal forcing and substrate legacy shape the biogeochemical organization of rooftop vs. ground-level urban gardens

Urban agriculture is expanding rapidly in densely populated cities, yet the ecological functioning of rooftop soils relative to ground-level gardens remains poorly understood. We evaluated soil carbon and nitrogen cycling, microbial activity, and broad microbial community structu...

Exploring the survivability of higher-order multiple protostellar systems – The case of VLA1623

Abstract Higher-order protostellar systems (≥3 components) are commonly observed in the early stages of low-mass star formation. A persistent question in star formation and evolution is whether these higher-order protostellar systems survive as gravitationally bound systems or di...

Deep seeding resistance in maize: selected after domestication or a strategy of its wild ancestors to escape underground animal burrowing?

Abstract Buried seeds avoid predation ensuring their survival until conditions are suitable for germination. The ability of seedlings to emerge from the soil depends on soil characteristics, burial depth, and the skotomorphogenic program of each species. This process is of intere...

Implementing milestone-based assessment to document surgical competence progression in an obstetrics and gynecology residency program: a mixed-methods study from Latin America

Competency-based medical education emphasizes outcomes and developmental progression, yet traditional numeric evaluations often fail to capture changes in surgical competence over time. Surgical milestones offer a structured framework for formative assessment, but their adaptatio...

Adaptive Laboratory Evolution of the Hydrocarbonoclastic Marine Strain Rhodococcus ruber MSA14 to High Pyrene Concentrations

Rhodococcus ruber MSA14, isolated from oil-polluted coastal sediments in Baja California, Mexico, has previously been shown to degrade pyrene, highlighting its potential for polycyclic aromatic hydrocarbons (PAH) bioremediation. In the present study, MSA14 was subjected to adapti...

Standardized Sechium edule root extract attenuates LPS inflammation alongside transient STAT3 phosphorylation and an interleukin 10 biased macrophage response

Chronic low-grade inflammation is sustained by macrophage activation toward proinflammatory states and contributes to cardiometabolic and degenerative disorders. Given the growing interest in evidence-based medicinal plants, we investigated whether a hydroalcoholic root extract o...

Poincaré–Birkhoff–Witt theorems in higher algebra

We extend the classical Poincaré-Birkhoff-Witt (PBW) theorem to higher algebra by establishing a version that applies to spectral Lie algebras. We deduce this statement from a basic relation between operads in spectra: the commutative operad is the quotient of the associative ope...

A mathematical model for the efficient control of the New World screwworm

Abstract An outbreak of New World screwworm has recently been spreading across Mexico, after more than 30 years of absence. The sterile insect technique, which consists of the massive release of sterilized males, has proven to be one of the most efficient methods for controlling...

Continuous Monitoring of the Photocatalytic Degradation of Levofloxacin Using an Impedimetric Sensor-Based System

Developing portable and reliable systems for online monitoring of antibiotic degradation in water is essential for studying, optimizing, and improving their efficiency. In this work, we introduce an impedimetric sensor-based system for online monitoring of the photocatalytic degr...

Explosive molecular outflows

Abstract About 15 years ago, a new type of extreme (with kinetic energies of $$\textrm{E}_k \sim 10^{47-49}$$ E k ∼ 10 47 - 49 erg) molecular outflows associated with very luminous ( $$\ge $$ ≥ $$10^5$$ 10 5 $$\textrm{L}_\odot $$ L ⊙ ) and massive ( $$10^3$$ 10 3 $$\textrm{M}_\od...

Preliminary Clinical Outcomes of an Alternating-Current-Assisted Implant Surface Decontamination Protocol: A Prospective Case Series with 12-Month Follow-Up

Background: Treatment of peri-implantitis remains challenging because biofilm removal from microstructured implant surfaces is often incomplete. The present study is an uncontrolled, prospective feasibility case series involving six patients (six implants), not a controlled clini...