Tufts University

Trimetallic Single-AtomAlloys: Active Site Synergyor Most Reactive Atom Dominance? The Case of RhPtCu(111)

Abstract Elucidating how different atomically dispersed dopant atoms interact and control reaction pathways is central to the rational design of trimetallic single-atom alloys (SAAs). Here, we investigate CH3rI decomposition on Cu(111), PtCu(111), RhCu(111), and RhPtCu(111) trime...

Directed Evolution of an Escherichia coli Secretor Strain Using the Curli Pathway

Abstract A key goal of many bacterial engineering projects is to produce protein, due to their potent chemical and material functions. However, recombinant proteins are usually produced intracellularly, and secreting arbitrary proteins directly into an extracellular environment i...

“What Are You Fighting for?” Working With Couples in Conflict

ABSTRACT Couples in conflict often become trapped in recursive cycles of complaint and defensiveness, leading to demoralization and disconnection. This is a problem for the couple and the therapist. This paper offers the idea that when couples engage in conflict, it is often a re...

The p97 adaptor p47/NSFL1C is necessary for stress granule dissolution after heat stress

Abstract Stress granules form in response to diverse cellular perturbations to sequester translation components until the stress is resolved. Stress granules are composed of RNA–protein assemblies in membrane-delimited structures and must be rapidly disassembled to release compon...

Rural-Urban Disparities in Contemporary Systemic Therapy for Advanced Prostate Cancer

This cross-sectional study examines the associations of rural-urban residence and race with receipt of systemic therapy for advanced prostate cancer.

Host CD59 potentiates the type III secretion system in Yersinia pseudotuberculosis

Type III secretion systems (T3SS) play critical roles in disease for many Gram-negative pathogens. Although the structural details of T3SS assembly have been extensively studied, the intimate interactions between T3SS components and the target host plasma membrane are poorly char...

Intraoral Scanners: Enhancing Dental Education

ABSTRACT Introduction This study evaluated how integrating intraoral scanners (IOS) into Digital Dentistry and Operative II courses at Tufts University School of Dental Medicine (TUSDM) influenced second‐year dental students' perceived understanding of ceramic inlay preparations...

Pangenome analyses reveal divergence and extensive introgression in two global corn pests

Introgression between closely related species can profoundly influence evolutionary trajectories, yet how genomic divergence interacts with introgression, especially in invasive hybridization, remains insufficiently understood. Structural variants (SVs), particularly chromosomal...

A biodegradable piezoelectric vertebral implant for programmable electro-neuromodulation in spinal cord injury

Spinal cord stimulation has emerged as a promising therapeutic strategy for spinal cord injury (SCI), yet conventional electronic implants remain limited by surgical risk and long-term safety concerns. We introduce a biodegradable piezoelectric cryogel (Piezo Gel) that enables pr...

Stability‐Enhanced Therapeutic Artificial Cells Based on a Lipid–Polymer Integrated Architecture

ABSTRACT Current artificial cells often lack robustness in the face of the complex physiological milieu. Additionally, the strategies for mimicking natural cargo exchange mostly rely on biological techniques, which involve integrating native channel proteins or adopting intact na...

Review of Particle Physics *

The Review summarizes much of particle physics and cosmology. Using data from previous editions, plus 3,200 new measurements from 903 papers, we list, evaluate, and average measured properties of gauge bosons and the recently discovered Higgs boson, leptons, quarks, mesons, and b...

Identifying generative AI use among genuine responders in online survey research

Everyday use of AI has introduced more AI-generated content into surveys, diluting insights and distorting findings. While the concern about agentic “bots” responding to surveys is now widely recognized by most researchers, this comment discusses the simultaneous rise in use of A...

Epigenetic changes reveal that vitamin B12 intake is associated with lower insulin resistance in older adults

Abstract Background Dietary choices influence both risk and development of type 2 diabetes (T2D), but the precise mechanisms remain incompletely described. Dietary intake and lifestyle behaviors can alter epigenetic states with subsequent modulations on gene expression which then...

Manipulation of biological systems by self-defecting and foreign agents

Biological systems maintain structure and function through hierarchical control, redundancy and surveillance across scales. These same features create leverage points for agents that establish a persistent presence in host systems, including foreign agents such as pathogens, para...

Characteristics and Management of Xylazine-Associated Wounds: A Systematic Review of Published Cases.

BACKGROUND: The rise in xylazine-adulterated fentanyl and heroin has been designated as an emerging public health threat due to a devasting pattern of xylazine- associated wounds associated with its injection. This study was undertaken to systematically characterize patient and w...

A network approach with motion sequencing reveals hidden patterns of repetitive behavior in a pre-clinical model of epilepsy

Epilepsy is the 4th most prevalent neurological condition with 50 million cases worldwide. Patients with epilepsy bare a disproportionate burden of cognitive decline and psychiatric disorders which remain poorly understood and go unaddressed by current anti-epileptic treatments....