Tokyo University of Agriculture and Technology

Engineering a Highly meta -Selective Biphenyl Monooxygenase for the Biosynthesis of High-Value Polymer Precursors

Abstract The meta-selective C–H functionalization of aromatic substrates lacking meta-directing electron-withdrawing groups remains challenging. To engineer the regioselective enzymatic conversion of biphenyl (BP) to 3,3′-dihydroxybiphenyl (33DHBP), an industrial precursor to hig...

Natural factors, not land use type, determine topsoil mercury levels in the urbanized mosaic of the Hengduan Mountains, Qinghai-Tibet Plateau, China

Context It is widely recognized that contaminants in urban topsoil can present substantial threats to ecosystems and human health. Mercury (Hg) is a persistent pollutant arising from both anthropogenic (industrial and transport emissions) and natural (e.g. biomass burning, weathe...