Tohoku University

Associations of neurodevelopmental traits and adverse childhood experiences with problem gambling: A nationwide cross‐sectional study

Abstract Aim Attention‐deficit/hyperactivity disorder (ADHD) is a recognized related factor for gambling problems. Although ADHD frequently co‐occurs with autism spectrum disorder (ASD) and adverse childhood experiences (ACEs), the interaction of these factors on gambling has not...

Rural community revitalization through disaster tourism in Japan

The Great East Japan Earthquake and Tsunami (GEJET) in 2011 precipitated a profound socio-economic crisis in the Tohoku region, exacerbating pre-existing depopulation and aging trends. In response, the Japanese government’s “New Tohoku” initiative has prioritized rural community...

Factors associated with prolonged hospital stay in mandibular condylar fractures: a multicenter retrospective study in Indonesia

Mandibular condylar fractures constitute a significant proportion of maxillofacial trauma and are associated with functional impairment and increased healthcare utilization. However, factors associated with the duration of hospital stay remain insufficiently understood, particula...

Serial ultrafine endoscopic assessment of fibrin deposition and neomembrane formation in peritoneal dialysis patients using low glucose degradation product fluid

Preservation of the peritoneum is essential for the safe continuation of peritoneal dialysis (PD). Although PD fluid with low glucose degradation products (low GDP) are widely used, objective macroscopic assessment of the peritoneum during ongoing PD remains limited. We therefore...

Visualization of droplet splashing and droplet trajectory and theoretical prediction of a droplet motion on the geothermal turbine bucket

Abstract Understanding liquid behavior on the surface of rapidly rotating turbine blades is essential for clarifying drain formation in wet-steam turbines. However, direct experimental visualization of droplet impact and subsequent liquid transport under the combined conditions o...

Two stress-responsive kinases suppress ferroptosis by activating antioxidant programs under mild oxidative stress

Cancer cells maintain chronically elevated levels of reactive oxygen species (ROS) while relying on robust antioxidant programs to preserve redox homeostasis and viability. Although therapeutic strategies that disrupt this balance to induce lethal oxidative stress and ferroptosis...

Predicting Poor Efficacy of Cabozantinib in Advanced Renal Cell Carcinoma by Exploratory Metabolic Pathway Analysis and In Vitro Verification

ABSTRACT Background Cabozantinib (CABO) is currently an essential drug for first‐line and sequential therapy in the treatment of advanced renal cell carcinoma (RCC). Predicting its therapeutic efficacy will enable efficient drug selection and improve the prognosis of patients. We...