Tohoku University

Cytochrome c is Highly Compact upon Transfer into the Gas Phase from Strong Acids as Revealed by High-Pressure ESI Ion Mobility-Mass Spectrometry

Abstract A substantial increase in the acidity of the protein solution (e.g., from pH 2 to pH 1) is known to induce the compaction of fully unfolded proteins, such as cytochrome c, into a non-native yet highly compact molten globule state, referred to as the A-state. In this stud...

The Evolution of Neoadjuvant Treatment for Resectable Esophageal Squamous Cell Carcinoma: Past Achievements, Current Standards, and Future Perspectives

Neoadjuvant treatment has become an integral component of multidisciplinary management for resectable esophageal squamous cell carcinoma (ESCC). Over recent decades, treatment has evolved from surgery alone to postoperative chemotherapy, neoadjuvant chemotherapy, intensified syst...

Relationship Between Anterior–Posterior Plantar Reaction Force Distribution and Gait Speed in Post-Stroke Patients

Background: Gait speed is an important indicator of walking ability in post-stroke patients. Although gait speed is associated with anterior–posterior reaction force (AP RF), how AP RF is distributed across the plantar surface and whether this distribution is associated with gait...

Probabilistic tsunami risk assessment based on submarine active faults and their possible interactions in the sea of Japan

Abstract The Sea of Japan coastal areas have experienced tsunami damage caused by submarine active seismic faults. Large uncertainties remain regarding seismic activity of these faults and the following tsunami. Probabilistic tsunami risk assessment (PTRA) enables the evaluation...

Multi-AI agent framework reveals the “oxide gatekeeper” in aluminum nanoparticle oxidation

Aluminum nanoparticles (ANPs) are among the most energy-dense solid fuels, yet the atomic mechanisms governing their transition from passivated particles to highly reactive states remain elusive. This stems from a fundamental computational bottleneck: Ab initio methods offer quan...

Amplitude source location for volcanic earthquakes using source location-dependent amplification corrections: Application to Izu Oshima volcano, Japan

Summary The amplitude source location (ASL) method has been widely applied to volcanic earthquakes that do not show clear wave onsets at active volcanoes. To reduce the effects of shallow velocity structures just beneath seismic stations, observed amplitudes are generally correct...

Mathematical Analysis and Experimental Implementation of a Self-Calibration Method for Ultra-Precision Displacement Sensors

This paper starts from a revisit to the self-calibration concept of displacement sensors proposed previously by Kiyono et al. In this self-calibration scheme, two displacement sensors are used to perform a mutual calibration operation to determine their linearity error components...

Surrogate Computational Homogenization Enhanced by Partition‐of‐Unity RBF Interpolation With Decision Trees

ABSTRACT This study enhances a framework of surrogate computational homogenization (SCH) using decision tree‐based partition‐of‐unity radial basis function (PU‐RBF) interpolation for three‐dimensional finite‐deformation two‐scale analysis. The method addresses the scalability lim...

Spectral signatures of zenith sky radiance from surface-based sky radiometers: implications for clear- and cloudy-sky detection

Abstract. Accurate identification of clear- and cloudy-sky conditions is essential for reliable aerosol and cloud retrievals from ground-based remote sensing observations. This study investigates the spectral characteristics of zenith radiances measured by SKYNET sky radiometers...

Screening strategies for the early detection of non-cardia gastric cancer in low- to moderate-prevalence regions: Asia-Pacific gastroesophageal cancer congress consensus 2026

Abstract Background Gastric cancer (GC) remains a major global health burden, and early detection is essential for improving patient outcomes. Although GC screening has been widely implemented in East Asian countries with a high disease burden, the optimal screening strategy for...

Developing a Comprehensive Public Health Nursing Practice Model for Promoting Social Inclusion Among Populations Experiencing Social Exclusion: A Qualitative Study

ABSTRACT Aims To develop a comprehensive practice model delineating public health nursing practices that promote social inclusion and illustrate their outcomes in Japan. Design Qualitative descriptive research design. Methods Semi‐structured interviews were conducted with 12 publ...

Machine Learning on Heterogeneous, Edge, and Quantum Hardware for Particle Physics

The next generation of particle physics experiments will face an era of challenges in data acquisition, due to unprecedented data rates and volumes along with extreme environments and operational constraints. Harnessing these data for scientific discovery demands real-time infere...

Unverified Hazard Information and Visit Intention in Mountain Recreation: Within-Person Response Patterns and Implications for Sustainable Destination Management

Unverified hazard information may influence destination visit decisions before its veracity is established. This study examined visit intention across three hypothetical situations characterized by different information environments involving the emergence of unverified hazard in...

Neglected carbonation effect on moisture profiles in hardened cement paste during short-term drying

This study investigates the influence of atmospheric CO₂ on moisture transport during drying in cementitious pastes with different microstructures, namely ordinary Portland cement (OPC), volcanic glass powder (VGP), and limestone-calcined clay cement (LC 3 ) pastes. To isolate th...

Resolution Dependence of the Climate Feedback Parameter in Km‐Scale Climate Models

Abstract Global storm‐resolving models (GSRMs) provide new opportunities to investigate the climate response to warming with explicitly resolved deep convection. However, the limited number of existing studies has so far precluded the systematic assessment of similarities and dif...

Human-centred design approaches to tsunami mitigation under sea level rise in Kesennuma, Japan

Abstract. Human-centred design (HCD) is increasingly prioritised as studies show human experience is critical in infrastructure use, and recent policies call for more socially responsive design. Tsunami impacts intensify as sea level rise (SLR) raises baseline water levels and re...

Diagnostic Utility of Full‐Length BP180 and Native BP180 ‐α6β4 Integrin Complex ELISAs in Serologically Inconclusive Mucous Membrane Pemphigoid

ABSTRACT Mucous membrane pemphigoid (MMP) is a chronic autoimmune subepithelial blistering disorder of mucosal surfaces that can cause irreversible scarring, blindness, or dysphagia. Early diagnosis is challenging because histopathology is nonspecific and conventional BP180 NC16A...

Coupling the Spin State Switching and CO2 Adsorption Operating at Different Temperatures in a Breathing Metal–Organic Framework

Gas-responsive magnetic response arising from spin-crossover (SCO) phenomena is rare yet highly attractive for molecular sensing and spintronics. However, it remains unclear how gas uptake influences SCO behaviour when the two phenomena occur in separate temperature regimes. Here...

Development of scalable cross-flow purification process for transparent conductive film quality silver nanowires

Silver nanowires (Ag NWs) exhibit high conductivity and excellent light transmittance, making them suitable for use in flexible displays, touch panels, and solar cells. However, Ag NWs synthesized using methods such as the polyol process contain a significant number of silver nan...

Regional effect of population-based programs promoting salt reduction and potassium intake in Hokkaido: a post hoc analysis of the PoSPIP

Abstract The Population-based Sodium/Potassium Improvement Program is a nonrandomized population-based intervention implemented by the Japanese Society of Hypertension across multiple municipalities and workplaces in Japan. This post hoc regional analysis focused on two municipal...