The University of Queensland

Implementing evidence in residential aged care facilities: a longitudinal multi-method evaluation of knowledge broker evolution

Background Knowledge brokers act as intermediaries to bridge evidence-to-practice gaps. Limited evidence describes how the knowledge broker role in health settings evolves over time. This study aimed to (a) examine the evolution of knowledge broker activities over a 12-month impl...

Terminology for describing the 24-h cycle of physical activity, sedentary behaviour, and sleep: a scoping review

Abstract Background Physical activity, sedentary behaviour, and sleep are three behaviours which occupy the 24-h cycle and interact to influence a multitude of health outcomes. Different terms are currently used to describe these behaviours collectively (e.g., movement behaviours...

The lived employment experiences and support needs of persons with Younger Onset Dementia within Australia

Background There is limited evidence on the perspectives and support needs of persons with younger onset dementia (YOD) within employment. This poses challenges for supporting this demographic within the workplace and during their transition to retirement. Objective The aim of th...

Understanding current practice and challenges to the implementation of rehabilitation for people living with dementia: insights from health professionals in Malaysia

PURPOSE: To examine Malaysian health professionals' knowledge, attitudes, confidence, beliefs, and practices regarding dementia rehabilitation, and to identify perceived barriers and enablers. MATERIALS AND METHODS: An online survey assessed dementia knowledge (DKAS), attitudes (...

Safety begins at home: supply chain power and workplace safety

Purpose This paper examines how a major corporate customer's supply chain power affects its workplace safety records. Using the social exchange theory and the resource-based view of the firm as theoretical frameworks, the study examines how relational dynamics and trust between c...

Effects of maternal and paternal smoking on offspring cardiometabolic risk factors in adulthood: a multi-method intergenerational Mendelian randomization study

Abstract Background Parental smoking has been linked to several adverse offspring cardiometabolic outcomes; however, evidence is conflicting regarding the causal and long-term nature of these associations. Methods We investigated the effects of maternal and paternal smoking, capt...

Gender Inequality and Social Capital in Academic Finance Networks

Abstract Finance academia remains heavily male dominated, yet the mechanisms driving women’s underrepresentation are not fully understood. This study examines how co-authorship networks shape gendered access to and mobilisation of social capital by integrating Social Capital Theo...

Vancomycin optimised dosing regimens for critically ill patients receiving renal replacement therapy

Optimal dosing of vancomycin in critically ill patients receiving renal replacement therapy (RRT) is uncertain due to high pharmacokinetic variability. We aimed to develop individualised vancomycin dosing recommendations that optimise efficacy while minimising toxicity. Prospecti...

Unveiling differential gene expression and pathways in clear cell renal cell carcinoma with sarcomatoid transformation

Background Sarcomatoid transformation in clear cell renal cell carcinoma (ccRCC) is associated with highly aggressive clinical behaviour and poor prognosis. The molecular basis underlying this transformation remains poorly defined. Methods Formalin-fixed paraffin-embedded tumour...

Electrodeposition-initiated, self-catalyzed growth of 2D amorphous Fe-group metal–boron alloy mesoporous films

Two-dimensional mesoporous amorphous metallic films, particularly those based on earth-abundant Fe-group metals (Ni, Co, Fe), are highly promising for various applications due to their high surface area, structural isotropy, and abundant undercoordinated sites. However, synthesiz...

“Just a number” – larger-bodied women’s experiences of weight-centric and weight-inclusive maternity care: a national online photovoice study

Abstract Background Weight stigma is a pervasive issue in healthcare, including maternity care, characterised by bias, discrimination, and exclusion. Experiencing weight stigma can negatively impact health outcomes, self-esteem, and engagement with care. While existing literature...

Enhancing passing ability of coral aggregate concrete by optimising wet packing density

This study employed sea sand (SS) and coral aggregate (CA) to completely replace river sand and natural coarse aggregate in the production of seawater sea sand coral aggregate concrete (SSCAC). However, the porous characteristics of CA increase the surface friction between the ce...

Development and validation of a real-time polymerase chain reaction for the detection of Haycocknema perplexum.

dilution (Ct value 39.6) for SSU-PCR, making the latter a more sensitive assay for detecting lower concentrations of organism in the patient biopsy. The sensitivity of fresh frozen samples was superior to FFPE samples. All but one sample was negative following treatment. Feasibil...

Expedited research and approval of medicines for drug-resistant bacterial infections in children.

Multidrug-resistant pathogens cause severe infections with substantial morbidity and mortality in neonates, infants and children, as they do in adults. However, the approval of therapies for multidrug-resistant infections in paediatric patients often lags years behind approval fo...

Icotrokinra (ICO), a Novel Targeted Oral Peptide, in Patients (Pts) with Psoriatic Disease: Exploratory Assessments from a Phase 2 Psoriasis (PsO) Study Informing a Phase 3 Clinical Program in Psoriatic Arthritis (PsA)

Objectives PsA affects ~20-30% of patients with PsO, causing articular inflammation and impaired quality of life. ICO, a novel targeted oral peptide that binds IL-23 receptor, showed greater clinical response rates vs placebo and a favorable safety profile in moderate-to-severe p...