The University of Queensland

Outcomes and associated risk factors among hospitalisations attributed to invasive group A streptococcal disease in Northern Queensland, Australia: a 21-year population-based data linkage study

Abstract Purpose Invasive group A Streptococcus (iGAS) disease is associated with substantial morbidity and mortality. This study aimed to assess the outcomes of iGAS infection and associated risk factors in Northern Queensland, Australia. Methods A retrospective cohort study was...

Robust inference and correlates from genetic associations with personality

Personality traits describe stable differences in how people think, feel and behave, and how they interact with and experience their social and physical environments1,2. Many questions remain unanswered about associations between DNA and personality traits, such as their robustne...

Intelligent Safety Assessment of Island Longwall Roadway Integrating Asymmetric Physical Features and Cost-Sensitive Learning

Roadways serving island longwall panels are highly susceptible to severe asymmetric deformation under extreme eccentric loading from multiple adjacent goafs. To address the difficulties in characterizing the surrounding rock load imbalance and the high false-negative rates of con...

Direct‐To‐Home Tele‐Neuropsychological Assessment in Older Adults: A Systematic Review

ABSTRACT Background Neuropsychological assessment via remote videoconference and telephone administration in the home setting (i.e., direct‐to‐home tele‐neuropsychological assessment) could increase service provision to older adults. However, current evidence has not yet been syn...

Pedagogical Lessons From Teaching Telehealth via Online Modes: A Systematic Review

Interest in telehealth has led to an increase in the availability of online telehealth courses. Understanding student perspectives of the learning experience and how the courses equip students with the skills for their future professions is warranted. To this end, five health, ed...

Experimental constraints on the differentiation of CM-like planetary embryos

This study investigates the onset of differentiation of hydrous (ice-bearing) planetary embryos in the early Solar System. To do so, we conducted high-pressure (1 GPa) melting experiments on a CM2 chondrite (MCY12002) across a temperature range of 1050-1400°C, with durations vary...

The Effects of Continuous Venovenous Hemofiltration on Immunosuppressive Drug concentrations in an Ex‐Vivo Model of the critically Ill Adult: (CITRIC) study

BACKGROUND: The pharmacokinetics of immunosuppressive drugs during continuous kidney replacement therapy (CKRT) modalities such as continuous venovenous hemofiltration (CVVH) are poorly understood, yet these drugs are crucial for transplant and critically ill patients. METHODS: A...

A Triple‐Site Engineered Heterojunction Photocatalyst for Full‐Spectrum NH 3 Synthesis via Synergistic Promotion of Water Oxidation and Nitrate Reduction

ABSTRACT Photocatalytic nitrate reduction reaction (NitRR) represents a sustainable approach to convert nitrate pollutants to valuable NH 3 . However, the performance of state‐of‐the‐art photocatalysts is hampered by insufficient near‐infrared (NIR) light utilization and sluggish...

Deep Network Reparameterized Full‐Waveform Inversion From Sequential to Simultaneous Sources With Adjoint‐State Method

Abstract Full‐waveform inversion (FWI) relies on sequential‐source (SQ) workflows for high imaging precision, while simultaneous‐source (SML) encoding drastically accelerates computation but introduces irreversible wavenumber discontinuity artifacts in hybrid‐domain implementatio...

The indirect effects of cognitive function in the association between stroke and quality of life among older adults in a rural community: A cross-sectional study

Abstract Purpose We examined whether cognitive function statistically accounted for associations between stroke and quality of life (QOL). Methods A cross-sectional survey included adults aged ≥ 60 years in Segamat, Malaysia. Cognition was assessed using the Identification and In...

Housing discrimination as a field in the making: institutional coupling, epistemic accumulation, and the uneven production of knowledge (1972–2022)

Abstract Housing discrimination remains a persistent source of inequality in access to housing and related life chances. Yet the evolution of academic knowledge on this phenomenon has rarely been examined as an object of inquiry in its own right. This article asks how research on...

Clinically significant hypokalaemia and the utilisation of cardiac telemetry in hospitalised adults

Hypokalaemia is one of the most common electrolyte abnormalities in hospitalised patients, with moderate (2.5–3.0 mmol/L) to severe (< 2.5 mmol/L) deficiency associated with an increased risk of cardiac arrhythmias, prolonged hospitalisation, and inpatient mortality [1]. While cl...

Nigral DJ-1 gene knockout in tree shrews can induce phosphorylated α-synuclein aggregation and all key phenotypes of Parkinson’s disease

Abstract DJ-1 is a genetic factor associated with Parkinson’s disease (PD), and altered DJ-1 function has been implicated in PD pathogenesis. However, DJ-1 knockout mice fail to reproduce robust PD-like phenotypes or neuropathology, leaving the contribution of DJ-1 deficiency to...

Protein Binding Determination of Cefepime, Flucloxacillin, Meropenem, Piperacillin and Tazobactam by Ultrafiltration in Critically Ill Patients: The Choice of Device Matters

Therapeutic drug monitoring (TDM) and pharmacokinetic studies of beta-lactam antibiotics in critically ill patients aim to define optimal dosing and require accurate measurement of unbound drug concentrations. This study compared the performance of two ultrafiltration devices, Ce...

Advanced Materials for Biologics Delivery to Brain Tumors

ABSTRACT Brain cancer remains a major global health challenge due to its high morbidity and mortality. Current standard therapies are often limited by incomplete tumor resection, systemic toxicity, and the inability to effectively penetrate the blood‐brain barrier (BBB), which re...

Single-molecule long-read sequencing reveals transcriptome complexity and enhances annotation in wild rice

Wild rice species harbour extensive but largely uncharacterised transcriptional diversity that underpins key agronomic traits and represents a valuable resource for crop improvement. Here we integrate single-molecule long-read sequencing (Iso-Seq) with short-read RNA-seq to resol...

Syrona: an open-source visual analytics tool for pairwise comparison of health datasets in OMOP CDM

Abstract Background Health research increasingly relies on observational datasets that capture systematically different patient populations, affecting the representativeness, comparability, and transportability of study findings. Yet these differences are rarely quantified across...

The influence of host phenology on infection and severity of rachis tip dieback caused by flower blight pathogens in macadamia

Abstract Rachis tip dieback (RTD) is an emerging disease affecting macadamia racemes and is associated with the flower blight complex. However, the timing and site of RTD infections and the effects of these infections on flower development remain poorly understood. Trials were co...

MXene‐Confined Cobalt‐Rich Co 2 P Nanoparticles Enable Highly Reversible Conversion Reaction for Stable and Fast Sodium‐Ion Batteries

ABSTRACT Transition metal phosphides have attracted considerable attention as alternative conversion‐type anodes for SIBs because of their high specific capacities. However, their sodium‐storage mechanism typically shifts to an alloying reaction between P and Na + after the initi...

Tracking breast cancer progression using Methylscape

Abstract Cancer progression is intricately driven by epigenetic reprogramming, where aberrant DNA methylation patterns reshape gene regulation and cellular phenotypes. These alterations include promoter hypermethylation of tumour suppressor genes and global hypomethylation, colle...