The University of Queensland

Demographic and psychosocial factors associated with adjustment and reintegration to civilian life: a prospective and cross-sectional analysis of transitioning and ex-serving military personnel

The prevalence of reintegration and adjustment difficulties among military veterans transitioning to civilian life is high, with maladjustment linked to poor mental health and increased suicide risk. Identifying factors predictive of adjustment may inform the development of preve...

Impact of socioeconomic status on treatment and survival in multiple myeloma in Australia

<title>Abstract</title> Outcomes in multiple myeloma (MM) have improved significantly but remain heterogeneous. We assessed the impact of non-biological social determinants of health on treatment and survival outcomes in Australia using data from the Australian and New Zealand My...

Measuring Safer Opioid Use in Hospitals: Development of Consensus-Based Safety and Quality Indicators - a modified Delphi study

BACKGROUND: A significant contributor to preventable medication related harm is opioids. Within Australian hospitals, opioids have contributed to deaths, hospital admissions, and in-hospital related harm. Given these harms, there is a need to ensure opioids are used safely and th...

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

Glioblastoma (GBM) is a highly lethal brain cancer in which the calcitonin receptor (CT Receptor), encoded by the CALCR gene, is expressed in 78–88% of patient biopsies. Here, we investigate whether the CT Receptor plays a role in cancer cell survival. In cancer cell lines, knock...

More than just temperature: the effects of nest relocation on incubation environment and hatchling quality in green turtles (Chelonia mydas)

Abstract Nest relocation and shading are widely used conservation strategies intended to mitigate threats to marine turtle hatchling survival. However, these interventions may carry unintended fitness costs. Estimating such effects can be challenging, especially in the absence of...

Digesta dynamics, nutrition messaging and (ultra)processed food

There are two disparate approaches used to communicate nutritional attributes of foods, based on nutrient composition and food type. Nutrient content fails to account for the rate and site of nutrient absorption, and food type does not differentiate between diverse forms of the s...

Aphasia treatment research: a decision-making tool to guide the design of phased trials from the Collaboration of Aphasia Trialists (CATs) trials for aphasia panel

Background Systematic reviews of randomised controlled trials with meta-analyses indicate that speech and language therapy for aphasia after stroke is effective in improving communication. However, high-quality evidence to identify an intervention’s target population (who), regim...

A Multimodal Graph Framework for News Credibility Assessment and Propagation-Level Prediction

The rapid dissemination of misinformation through online social networks creates challenges for information reliability and network stability. We evaluate a multimodal framework that produces a credibility classification and a propagation-level prediction within a single processi...

Chilled and freeze-dried preservation of saltwater crocodile (Crocodylus porosus) spermatozoa

CONTEXT: Artificial insemination in farmed crocodiles is limited by poor sperm survival after cryopreservation, requiring alternative preservation strategies. AIMS: This study evaluated the effects of three extenders on saltwater crocodile (Crocodylus porosus) semen during chille...

Temporal co-occurrence in a community of subtropical Australian birds

Abstract With a view to creating a biodiversity baseline to monitor a rewilding effort, I estimated the community structure of birdlife in subtropical South-East Queensland, Australia. Community structure was derived from patterns of temporal species co-occurrence and principles...

Genetic Ablation and Multi‐Omics Profiling Reveal CEP55 as a Key Driver of Tumorigenesis in Diverse Cancer Models

ABSTRACT CEP55, a centrosomal protein frequently overexpressed in multiple cancers, is implicated in regulation of genomic instability and PI3K/AKT pathway activation, yet its role in tumor progression and the tumor microenvironment remains incompletely defined. Here, we develope...

An NLRP3 inflammasome inhibitor evoked dose-dependent anti-allodynia in the hindpaws of a rat model of chemotherapy-induced peripheral neuropathy

Abstract Patients receiving chemotherapy for cancer treatment may develop chemotherapy-induced peripheral neuropathy (CIPN), a type of neuropathic (nerve) pain that is often difficult to treat. First-line analgesic/adjuvant agents recommended for the treatment of neuropathic pain...

Subcultural desires: Attraction to twinks, jocks, and bears is associated with sexual preferences for specific body types, gender expressions, and racial groups

Sexual subcultures such as twinks, jocks, and bears have provided sexual minority men with a means of self-definition and social connection within a broader LGBTQIA+ community. The present study explores the preferences associated with attraction to these subcultures, shedding li...

Mapping System Vulnerabilities in Anaesthesia Safety: A Role‐Based Inquiry in Response to Fatal Fungal Meningitis Outbreaks in Mexico

ABSTRACT Objectives Unsafe anaesthesia practices in Mexico have contributed to repeated outbreaks of fatal fungal meningitis, exposing broader health system vulnerabilities. This study aimed to analyse how structural weaknesses in perioperative care, spanning governance, workforc...

Development and Validation of the Melanoma Cancer Awareness Measure

<ns5:p>Background In the UK, the time taken to recognise a melanoma symptom and seek medical attention is the third longest of all cancers. There is no validated measure to assess public awareness of melanoma. We aimed to develop and validate a reliable Melanoma Cancer Awareness...

Co-designing ‘Focus on Frailty’, a digital frailty education course for hospitals: a qualitative study of healthcare professionals’ perspectives

Frailty is associated with negative outcomes and adverse events in hospitals; however, limited formal education on frailty exists in this setting. Healthcare professionals across disciplines have expressed a need and want for frailty education and training. This study aimed to ex...

Genetics of sensory nutrition

Sensory nutrition is an emerging research area that examines how chemosensory perception, particularly taste and smell, shapes dietary behaviours, nutritional status, and disease risk. Variation in how individuals perceive the same foods may help explain differences in diet quali...

Factors associated with bowel cancer screening participation among First Nations Peoples receiving home health care services in New South Wales, Australia

First Nations Australians consistently exhibit lower bowel screening participation rates than non-First Nations Australians. However, limited studies have been conducted to understand the factors associated with bowel cancer screening participation among First Nations Australians...

Triaging general practitioner referrals for specialist review to eConsultant – a pilot study

Background eConsultant is an asynchronous, digital, clinician-to-clinician advice service, giving general practitioners rapid remote access to specialist support for patient care. This study aimed to assess the feasibility, acceptability, and appropriateness of a model triaging s...

Multi-ancestry conditional and joint analysis applied to GWAS summary statistics

Manc-COJO (Multi-Ancestry Conditional and Joint Analysis) is a C++ software package for identifying independent association signals from multi-ancestry GWAS summary statistics. By jointly modelling association signals across ancestry groups while accounting for ancestry-specific...