The University of Queensland

Barriers to Understanding: Readability of Online Laryngomalacia Resources for Parents

Background Laryngomalacia is the most common cause of stridor in infants. Guidelines recommend parent education materials be written at a sixth to eighth-grade reading level, yet compliance of online resources remains unclear. Aim To evaluate the readability of online parental ed...

Temporal patterns and risk factors of clozapine-associated neutropenia: a nationwide population-based cohort study

Background Clozapine is the most effective antipsychotic for treatment-resistant schizophrenia, but neutropenia concerns continue to limit its use. Large real-world evidence on temporal risk patterns, re-initiation, and patient-level determinants remains limited. Methods We condu...

The effects of fungal decay on timber connections: a systematic review

Abstract Connections are critical for the integrity of timber structures, yet they are highly susceptible to reduced capacity due to moisture intrusion and subsequent fungal decay. While the effects of decay on clear wood are well documented, the impacts on the mechanical perform...

The future of high-dose, high-intensity neurorehabilitation: Consensus-based core recommendations from the fourth Stroke Recovery and Rehabilitation Roundtable

Objective: Convergent evidence indicates that high-dose, high-intensity rehabilitation (HDHI) improves outcomes beyond usual care after stroke, yet implementation remains limited. While questions of optimal dose, timing, and delivery format continue to be refined, the biological...

Temporal frictions in Australian horticultural value chains: Nature's time, power asymmetries and environmental consequences

The interdisciplinary agrifood literature has paid significant attention to power imbalances between supermarkets and suppliers, identifying fresh produce growers as particularly vulnerable to exploitative procurement practices. However, less work has examined the temporal charac...

Multiperiod Mean-Buffered Probability of Exceedance in Defined Contribution Portfolio Optimization

Abstract. We investigate multiperiod mean–risk portfolio optimization for long-horizon Defined Contribution plans, focusing on buffered Probability of Exceedance (bPoE), a more intuitive, dollar-based alternative to Conditional Value-at-Risk (CVaR). We formulate both precommitmen...

Effects of pre-spawning heat stress on the fecundity of Acropora aspera

<title>Abstract</title> Repeated bleaching events driven by heat stress have caused extensive coral mortality and long-term impairment in survivors. Following bleaching, larval production and recruitment decline, undermining reef recovery. On the Great Barrier Reef, such heat-str...

Advances in understanding of plasmid biology through the application of transposon insertion sequencing

Plasmids are extra-chromosomal DNA molecules capable of autonomous replication, stable inheritance in a bacterial population, and horizontal transfer to other bacteria. Plasmids can harbour auxiliary genetic material that contributes to host bacterial fitness, the most prominent...

Clinical outcomes of minimally invasive liver resection in patients with cirrhosis: A systematic review and meta-analysis

Backgrounds/Aims: The impact of cirrhosis on outcomes following minimally invasive liver resection (MILR) remains debated. This meta-analysis evaluates the effect of cirrhosis on perioperative outcomes in patients undergoing MILR. Methods: PubMed, Embase, CINAHL, Scopus, and Web...

Following the rules: which type 1 diabetes guidelines, protocols and recommendations are tertiary clinics in Australia following? A quantitative study

OBJECTIVES: This study characterises the use of type 1 diabetes (T1D) guidelines and protocols in Australian T1D clinics working with paediatric patients, and determines if management practices align with T1D-specific guidelines. METHODS: T1D clinic service leaders responded to a...

Optimal Policy Analysis for Monotonic (PO)MDPs and an Application to Fishery Management

<title>Abstract</title> We study the monotonicity properties of optimal policies for a class of fully/partially observable Markov Decision Processes (MDPs) motivated by renewable natural resource management. We first introduce a new class of deterministic monotonic MDPs with cont...

A machine learning approach to predict river hydrographs for water quality sampling

Abstract Hydrology and water quality are innately linked, as flow dynamics control the transport of pollutants within river systems. Consequently, the timing of sample collection in water quality monitoring programs strongly influences the accuracy of estimated pollutant loads. T...

Scaling up Genomics

Introduction: Genomic testing has substantial diagnostic and clinical value in nephrology, yet integrating testing into routine care requires service-level changes to ensure timely and equitable access. Methods: We conducted an observational cohort study at four tertiary centres,...

Incidence of and mortality risk from cardiovascular diseases after a cancer diagnosis: An umbrella review

Abstract Cardiovascular disease (CVD) is a leading cause of morbidity and mortality among cancer survivors, driven by the cancer itself, its treatments, and shared risk factors. Despite numerous systematic reviews and meta-analyses, the evidence remains fragmented and inconsisten...

A systematic review of early neuroimaging and neurophysiological biomarkers for post-stroke mobility prognostication

Abstract Background Accurate prognostication of mobility outcomes is essential to guide rehabilitation and manage patient expectations. The prognostic utility of neuroimaging and neurophysiological biomarkers remains uncertain when measured early post-stroke. This systematic revi...

Genome-Wide Association Study of Corneal Dystrophy Uncovers Novel Risk Loci and Enables Improved Polygenic Prediction of Fuchs Endothelial Corneal Dystrophy

Abstract Objective To identify risk loci for Fuchs endothelial corneal dystrophy (FECD) and improve a genetic risk prediction model. Design Genome–wide association study (GWAS), polygenic risk score (PRS) construction, and TCF4 CTG18.1 short tandem repeat (STR) length inference....

A systematic review of school-based mental health and wellbeing interventions for Aboriginal and Torres Strait Islander students in Australia (2015–2024)

Aboriginal and Torres Strait Islander young people’s wellbeing is grounded in culture, identity, and connection to community and Country. Schools offer unique opportunities to support wellbeing through culturally safe environments, trusted relationships, and community partnership...

A communication and messaging framework to increase public awareness of ultra-processed foods in Australia

Abstract Background Evidence of the health, environmental, and broader societal impacts of ultra-processed foods (UPFs) is rapidly accumulating, yet public awareness remains limited. This study aimed to develop a communication and messaging framework to increase public awareness...

Bidirectional associations between loneliness and physical multimorbidity and the mediating role of social inactivity

Physical multimorbidity and loneliness are increasingly recognised as public health concerns, but the nature of their potential relationships remains unclear. Here we report bidirectional associations between physical multimorbidity and loneliness in middle-aged and older adults...

Stäckel transform, coupling constant metamorphosis and algebraization of quasi-exactly solvable systems

Abstract We extend the application of the notions of the Stäckel transform and the coupling constant metamorphosis to quasi-exactly solvable systems. We discover that for a variety of one-dimensional and separable multidimensional quasi-exactly solvable systems, their sl (2) alge...