The University of Queensland

Repurposing Antibody-Drug Conjugates for Theranostic Targeting of Nectin-4 and TROP2 in Bladder Cancer

Abstract The application of antibody-drug conjugate (ADC) therapies in advanced bladder cancers may be improved through non-invasive molecular imaging and therapy with targeted radiation. Enfortumab and Sacituzumab, the antibody components for the ADCs PADCEV (Nectin-4 targeting)...

Third place visiting among mid-to-older adults: a cross-classified multilevel analysis

Background Visiting ‘third places’ outside of the home or workplace is associated with better health. For mid-to-older adults, visiting third places provides opportunities for social connectedness and physical activity that can support healthy ageing. We aimed to identify factors...

Vascular device practices in extremely preterm infants: an international cross-sectional survey

Abstract Objective To explore global practices in vascular device selection, securement, and monitoring for extremely preterm infants, and to assess regional variation. Study design A web-based cross-sectional survey was completed by one respondent per neonatal unit. Result We re...

Choroidal Melanoma Treated With Ruthenium‐106 Eye Plaque Brachytherapy: Results of an Australian Statewide Service From November 2020 to January 2025

ABSTRACT Introduction Uveal melanoma is a rare but aggressive malignancy, predominantly affecting the choroid. This study is the first retrospective review performed on adult choroidal melanoma patients treated with Ruthenium‐106 plaque brachytherapy in Queensland. Method The stu...

Girt By Sea: Re-imagining Australia’s Security

It’s hard to recall a time in recent memory when debates about Australian strategy and national security seemed more urgent or consequential. Alongside ongoing interstate conflicts in the Middle Ea...

Quantification of Urinary Free and Total Oxidative Stress Biomarkers and Their Differential Associations with Polycyclic Aromatic Hydrocarbon Exposure: A Bushfire Smoke Study

Abstract Urinary excretion profiles of free and metabolically conjugated oxidative stress biomarkers (OSBs) remain poorly characterized, potentially underestimating total excretion and biasing exposure–effect interpretation. In this study, the profiles of free, glucuronidated, an...

Conservation Messages as Catalysts of Post-Visit Action: Insights from Zoo and Aquarium Visitors

Zoos and aquariums face an urgent challenge to convey conservation messages that motivate visitors to change their environmental behavior. This study explores the reflections of 768 visitors to one of twelve zoos and aquariums in Australia, USA, and Canada regarding the features...

Clinical characteristics and semiological pitfalls in patients with focal epilepsy and functional/dissociative seizures: A comparative analysis of correct and incorrect initial diagnoses

OBJECTIVE: Both epilepsy and functional/dissociative seizures (FDS) can present with a wide variety of event manifestations which can appear similar in nature and contribute to misdiagnosis. Whereas many studies have addressed the misdiagnosis of FDS as epilepsy, research into th...

Benefits and Harms of Herbal Medicines for Preventing and Treating Acute Respiratory Infections: An Overview of Systematic Reviews

ABSTRACT Hundreds of herbal medicines are currently marketed for the management of acute respiratory infections (ARIs). However, there is uncertainty about their benefits and harms, and clinical guidance remains unclear. Our objective was to evaluate the benefits and harms of her...

Phage-based depletion of Variovorax reveals interactions within intact microbiomes

Abstract Background Testing microbial interaction hypotheses, including metabolite cross-feeding, remains a major challenge in microbiome research. Phages have the potential to probe organism-organism interactions within complex microbiomes yet are rarely utilised for this purpos...

Is the Marshmallow Test a Good Measure of the Capacity to Delay Gratification?

Children’s wait time in the marshmallow test is commonly interpreted as a measure of their capacity to delay gratification. However, children’s motivation to demonstrate the capacity to delay gratification in this task is contingent on them initially preferring and pursuing delay...

Theorizing Cross‐Boundary Strategizing as Situated in Multilayered Supply Chains: A Strategy‐as‐Practice Approach to Supply Chain Management

ABSTRACT Supply chain strategy is increasingly recognized as a multilayered phenomenon, with firms strategizing not only within their own boundaries but across supply chain tiers, jurisdictions, and wider regulatory and ecological systems. Yet most existing supply chain managemen...

Nutrient cycling, environmental outcomes and mitigation pathways in sugarcane agroecosystems: A comparative synthesis of Brazil and Australia

Sugarcane is a major tropical crop with strong potential to support climate-smart agriculture through efficient nutrient cycling, improved nitrogen use efficiency, biofuel production and enhanced soil carbon dynamics. However, environmental outcomes vary substantially across prod...

Secure Recommender Systems: A Co-evolutionary Survey of Vulnerabilities, Attacks, and Defenses

Recommender systems (RS) increasingly mediate what users see, buy, and believe, making them attractive targets for malicious manipulation. As RS have progressed from traditional collaborative filtering to deep learning and, most recently, LLM-driven designs, the landscape has co-...

Immune correlates of protection are exposure-dependent: evidence from the Dominican Republic

Immune protection against infection is often treated as a fixed property of a person’s immune response. But infection risk also depends on the number of infectious contacts a person experiences, which generally increases as community transmission rises. This matters for vaccine e...

Relations between Teachers’ and Students’ Social-emotional Competence: A Systematic Review and Multilevel Meta-analysis

Abstract Social-emotional competence (SEC) is strongly associated with key educational outcomes, including students’ academic achievement, engagement, and well-being as well as teachers’ effectiveness and occupational well-being. Although evidence for the extent and conditions of...

CONCUR: Benchmarking LLMs for Concurrent Code Generation

Leveraging Large Language Models (LLMs) for code generation has increasingly emerged as a common practice in the domain of software engineering. Relevant benchmarks have been established to evaluate the code generation capabilities of LLMs. However, existing benchmarks focus prim...

How Phylogenies Inferred from 46 Mitochondrial Genomes Informed the Systematics of the Australasian Genus of Ticks, Bothriocroton, with the Description of Three New Species

Background: We revised the taxonomy and identification of the species of the genus Bothriocroton in light of entire mitochondrial genomes and nuclear rRNA genes, scanning electron microscopy, and light microscopy. Methods: (i) phylogenetic trees inferred from entire mitochondrial...

Big data and psychiatry: advances, constraints and future directions.

Early work in psychiatry research, often involving single sites, small samples, and limited variables, has shifted to contemporary research involving multiple sites, large samples, and many variables. Such research raises important questions, including concerns about data quality...

Remarks on the conjectures of Capparelli, Meurman, Primc and Primc

Abstract In a series of two papers, S. Capparelli, A. Meurman, A. Primc, M. Primc (CMPP) and then M. Primc put forth three remarkable sets of conjectures, stating that the generating functions of coloured integer partitions in which the parts satisfy restrictions on the multiplic...