Tel Aviv University

From Rapid Progression to Long-Lasting Complete Response: A Wide Range of Ripretinib Activity for Metastatic GIST—A Real-World Cohort

Background: Ripretinib, a switch-control kinase inhibitor approved for advanced gastrointestinal stromal tumor (GIST), inhibits primary and secondary KIT and PDGFRA mutations. Real-world data from Western and Middle Eastern populations remain limited. We report outcomes from a mo...

PHANTOM: polymorphic honeytoken adaptation with narrative-tailored organisational mimicry contextually convincing cyber deception at scale

Honeytokens, decoy digital assets planted to detect and attribute unauthorised access, are a well-established primitive in cyber deception. Existing generation tools produce static, template-based tokens that lack organisational specificity and are identifiable by statistical, sy...

Elastic quantum coupling between free electrons and photons

The quantum coupling between free electrons and photons enables the application of quantum optics techniques in electron microscopy. For example, the phase of the electron wave function can be manipulated by passing the electron through an intense laser field. We develop here a q...

Quantum‐Mechanical Wave Functions in Singular Potentials: Linear and Nonlinear States

ABSTRACT It is known that the attractive singular potential gives rise to the quantum collapse in the framework of the three‐dimensional (3D) linear Schrödinger equation. This article summarizes theoretical results which demonstrate suppression of the collapse caused by this sing...

Three-dimensional optical vortices in nonlinear bessel waveguides

Abstract We explore the formation, stability, and propagation dynamics of light bullets carrying orbital angular momentum (vorticity) in Bessel-structured nonlinear graded-index waveguides. While these waves are prone to the collapse in uniform three-dimensional media, we demonst...

Enhancing short-term predictions of mortality risk for liver transplant candidates through random survival forests

MELD-based scores do not fully account for systemic and metabolic risk in liver transplant candidates, with notable gaps for those with metabolic dysfunction-associated steatotic liver disease (MASLD). In this retrospective, outcome-anchored, single-center proof-of-concept study,...

The Global Immune–Nutrition–Inflammation Index (GINI) as a Candidate Prognostic Marker in Patients with Cutaneous Squamous Cell Carcinoma Treated with Cemiplimab

Background/Objectives: Cutaneous squamous cell carcinoma (cSCC) is a highly prevalent malignancy. While Cemiplimab has transformed the treatment landscape across various disease stages, reliable pretreatment biomarkers for risk stratification remain lacking.. The Global Immune–Nu...

Psilocybin prevents chemotherapy-induced peripheral neuropathy through mitochondrial trafficking preservation

Chemotherapy-induced peripheral neuropathy (CIPN) is a disabling, often irreversible toxicity that affects millions of patients, limits life-saving cancer therapy, and lacks proven treatment. In this work, we show that as little as two doses of psilocybin before chemotherapy dura...

The impact of chronic loop diuretic therapy on urinary microbiology and clinical outcomes in hospitalized older adults

Urinary tract infections (UTIs) are common among hospitalized older adults and are closely linked to antibiotic exposure and antimicrobial resistance. Loop diuretics are widely prescribed in this population and substantially alter urine volume and composition. However, their pote...

Reference quality of OpenEvidence across five medical specialties

OpenEvidence (OE) is a retrieval-augmented clinical AI tool. We evaluated the references OE returned to 150 standardized prompts across five specialties, analyzing all 4979 citations. No reference was confirmed as fabricated; three abstracts had attribution errors. Most reference...

Towards a deep-learning genomic tool for risk stratification and diagnostic support in sporadic ALS

Abstract Background A variety of common and rare genetic factors have been implicated in the development of amyotrophic lateral sclerosis (ALS), and the evidence is that a genetic component is present in most affected individuals. However, our current understanding of ALS genetic...

Gestational diabetes in multifetal versus singleton pregnancies: A multicenter cohort study

Abstract Introduction Gestational diabetes mellitus (GDM) is associated with increased neonatal morbidity in singleton pregnancies, but evidence in multifetal pregnancies is limited. Current diagnostic thresholds are largely extrapolated from singleton data; It remains unclear wh...

IgG4-related endobronchial lung disease and HIV: a case report and review of the literature

Immunoglobulin G4-related disease (IgG4-RD) is a systemic inflammatory disorder which typically presents as multiorgan infiltration by polyclonal IgG4-positive plasma cells and responds well to immunosuppression such as systemic corticosteroids. The co-occurrence of IgG4-RD among...

Extended-Spectrum β-Lactamase-Producing Enterobacterales in Free-Roaming Cats in Israel

Amid the rising prevalence of antimicrobial resistance (AMR), attention is increasingly directed toward investigating additional factors that may contribute to or mediate its development, among which companion animals have emerged as a potential reservoir and transmission interfa...

Cauchy identities for staircase matrices

Abstract The well‐known Cauchy identity expresses the product of terms for indexing entries of a rectangular ‐matrix as a sum over partitions of products of Schur polynomials: . Algebraically, this identity comes from the decomposition of the symmetric algebra of the space of rec...

Engineering Atomically Precise Cu 4 I 4 Nanoclusters With Integrated Adsorption and Hydrogenation Functions for Efficient Photocatalytic Nitrate‐to‐Ammonia Conversion

ABSTRACT Photocatalytic nitrate reduction to ammonia offers a sustainable route that couples environmental remediation with nitrogen resource utilization. However, this transformation suffers from sluggish kinetics and insufficient hydrogenation, leading to poor selectivity and e...

Cosmic Radiation Dose‐Rates for Civil Aviation in the Middle East: Vertical Structure, Solar Modulation, and Comparison With Models

Abstract High‐altitude balloon measurements were conducted over southern Israel (30°35′N, 34°45′E; 850 m a.s.l., geomagnetic rigidity cutoff 10.3 GV) to characterize the vertical profiles of atmospheric ionization and radiation up to ∼35 km. Six balloon launches between October 2...

Comparing Parent–Child Shared Reading and Children’s Understanding of Non-Rhyming, Rhyming, and Magazine Information Texts: An Exploratory Study

The home and preschool settings serve as important contexts for children’s early language and literacy development. There is limited research on parent–preschooler shared reading and children’s comprehension of information texts that vary in their format, structure, or mode of pr...

Glycemic risk stratification in older adults with heart failure: the prognostic role of HbA1c in an aging society

Glycated haemoglobin (HbA1c) is central to diabetes mellitus (DM) management, but its prognostic value in older adults, aged ≥80 years, with heart failure (HF) remains uncertain. Thus, the study aimed to evaluate the association between HbA1c levels and all-cause mortality among...

Irritable Bowel Syndrome and Allergic Diseases: A Nationwide Study of 1.5 Million Adolescents

BACKGROUND: Recent evidence suggests an increased prevalence of irritable bowel syndrome (IBS) among individuals with allergic diseases, and several biological mechanisms have been proposed. This study aims to investigate the association between IBS and allergic diseases in a lar...