Institution
Shandong University
Recent research
- Society & EconomicsOpen access
Autism spectrum disorder (ASD) has a continuously rising global prevalence, imposing a heavy burden on affected families and society. Emotional and behavioural problems are the most common comorbidities of ASD and severely impair the long-term prognosis of affected children. Whil...
- Materials & Energy
ABSTRACT Treating infected bone defects remains a formidable clinical challenge due to robust bacterial antioxidant resistance and severe microenvironmental deterioration. Herein, an antibacterial biomimetic periosteum (ABP) is rationally engineered by in situ anchoring ultrasmal...
- Society & EconomicsOpen access
Online customer reviews provide rich evidence for product iteration, but their fragmented, multimodal, and competitive nature makes it difficult to convert user feedback into actionable priorities. This study proposes CompReview, a large language model-assisted framework for mult...
- BiologyOpen access
Roles of lactate and protein lactylation in neurogenesis and neurodegenerative disease
Neurodegenerative diseases are characterized by the gradual deterioration and impaired functionality of neuronal cells, which in turn results in the progressive decline of both cognitive capabilities and motor performance. Over the past few years, accumulating evidence has demons...
- Engineering & Technology
ABSTRACT Rechargeable Li–O 2 batteries have attracted significant attention as a next‐generation energy storage technology because of their extremely high theoretical energy density. However, practical implementation remains hindered by limited energy density, poor cycling stabil...
- Health & MedicineOpen access
Abstract Antimicrobial peptides (AMPs) are promising antibiotic alternatives, but current AI-based discovery often relies on sequence labels and lacks explicit modeling of peptide–membrane interactions. We developed Membrane-MaSIF, an MD-derived membrane surface matching model de...
- Climate & EnvironmentOpen access
Hydrophobic and salt-storage functionalization can impart anti-icing capability to asphalt, but the associated changes in rheological behavior should be evaluated concurrently. In this study, silica aerogel and potassium acetate-loaded diatomite were incorporated as hydrophobic a...
- Engineering & Technology
Sn–Pb Perovskite Laser Wireless Power Transfer for Medical Implants: A Perspective
ABSTRACT As global precision medicine advances toward chronic disease management and active health intervention, implantable medical devices are evolving from passive monitors into active therapeutic platforms. While subcutaneous bioelectronics, exemplified by pacemakers, are cor...
- Engineering & TechnologyOpen access
Abstract Achieving uniform, large-area interfacial layers remain a definitive barrier to the scalable manufacturing of solution-processed organic photovoltaics (OPVs). Conventional self-assembled monolayers (SAMs) frequently suffer from stochastic aggregation and incomplete cover...
- Climate & Environment
Microbially Driven Physicochemical Destabilization in Organic Matter Turnover
Abstract The persistence of organic matter has long been attributed to the intrinsic recalcitrance of complex biopolymers and the constraints of enzymatic degradation. However, across both marine and terrestrial ecosystems, structurally complex polymers such as chitin, cellulose,...
- Health & MedicineOpen access
SARS-CoV-2 continues to evolve. The subvariant BA.3.2 (Cicada), a derivative of the Omicron BA.3 subtype first detected in late 2024, harbors multiple spike protein mutations, ORF7 and ORF8 deletions, and has recently evolved sublineages (BA.3.2.1 and BA.3.2.2), rendering it a cr...
- Materials & Energy
Abstract Solar-driven interfacial steam generation technology is regarded as an effective method for freshwater production. Nevertheless, conventional evaporators suffer from weak light absorption and a trade-off between high evaporation rate and salt resistance, which restricts...
- Health & MedicineOpen access
Achieving early diagnosis of esophageal squamous cell carcinoma (ESCC) is crucial for reducing the disease burden. This study aims to identify potential serum protein biomarkers associated with the early diagnosis of ESCC in two independent populations and further develop diagnos...
- Society & EconomicsOpen access
Expressive prosody plays an important role in conveying emotion during oral poetry performance. This study investigated whether emotional prosody can serve as a perceptually robust cue for emotion judgment when semantic comprehension is unavailable. Experiment 1 confirmed systema...
- Health & MedicineOpen access
Oral nano-vaccines offer a non-invasive approach for cancer immunotherapy by combining gastrointestinal delivery with mucosal immune induction and systemic antitumor immune activation. However, their development remains constrained by antigen degradation in the gastrointestinal t...
- AI & Computing
Systematic Evaluation of Graph Neural Networks for Ligand-Based Virtual Screening on ChEMBL Datasets
Abstract The performance of target-specific, ligand-based virtual screening models is strongly influenced by dataset characteristics, including data availability, class imbalance, and evaluation strategies. In this work, we perform a systematic evaluation of graph neural networks...
- Climate & Environment
Abstract 4-Alkylphenols (APs), as typical endocrine-disrupting chemicals (EDCs) widely present in the environment and the human body, have been implicated in the disruption of lipid metabolism. However, the structure-activity relationships (SARs) and underlying mechanisms of thei...
- Society & EconomicsOpen access
The integration of AI into higher education provides new opportunities for supporting learning in interdisciplinary contexts and fostering entrepreneurial development. However, previous research has mainly focused on AI technology adoption, with limited attention paid to its broa...
- Engineering & TechnologyOpen access
Weld-FHG-YOLO: A Lightweight Multi-Frequency Feature Fusion Network for Weld Keypoint Localization
Accurate weld keypoint localization is an important visual perception task for robotic welding, weld tracking, and intelligent manufacturing. However, weld keypoints in line-structured light images are usually small, weakly textured, and easily affected by reflections, noise, and...
- Engineering & TechnologyOpen access
Consolidated bioprocessing (CBP) using Acetivibrio thermocellus offers a promising route for the direct conversion of recalcitrant lignocellulose into ethanol. In this study, a synergistic co-culture system comprising A. thermocellus C1 and Thermoanaerobacterium thermosaccharolyt...