Seoul National University

Monolithic three-dimensionally integrated memristor-thin-film transistor for electrically programmable multimode reservoir computing

Reservoir computing offers an efficient framework for processing temporal information, but most hardware reservoirs exhibit fixed or narrowly tunable dynamics determined by intrinsic material relaxation time. A monolithically integrated memristor-thin-film transistor reservoir ke...

Sensory gamma entrainment in older adults with or without cognitive impairment: a systematic review and exploratory meta-analysis

Gamma entrainment using sensory stimulation (GENUS) is a noninvasive approach under investigation in older adults with and without cognitive impairment, including Alzheimer’s disease; however, human evidence remains scattered across structural, functional, biomarker, electrophysi...

Recoverability, utility, and source-content exposure in compressed multilingual text representations

Reusable text representations are routinely cached and compressed, yet downstream utility and source-content exposure are rarely measured together. We evaluate token sequences and pooled vectors across six languages, five encoders, classification and dense retrieval, matched atta...

Combination strategy of photothermal therapy and targeted IFN-β mutein priming elicits a durable abscopal effect

Metastatic tumors remain difficult to cure due to frequent dissemination and recurrence. While photothermal therapy (PTT) can trigger abscopal effects, PTT monotherapy often fails to sustain systemic immunity. Here, we investigated a tripartite strategy combining PTT, a tumor-tar...

Distributed quantum certification with Clifford encoders

Quantum state certification concerns a resource-efficient way to verify whether a quantum device produces a prescribed target state without reconstructing the state in full, making it a fundamental primitive for validating quantum systems. We consider the private-coin model with...

Association between introduction of 13-valent pneumococcal conjugate vaccine and burden of hospitalized adult pneumococcal disease in South Korea – a population-based retrospective database study

Abstract Background Information on the burden of pneumococcal disease and its association with vaccination in South Korea remains limited. This study aims to examine the incidence rate, case fatality rate, healthcare resource utilization and costs of pneumococcal disease in adult...

Interpretable multimodal retrieval augmented diagnosis for breast ultrasound with multinational clinical validation and reader study

Breast ultrasound is central to breast cancer diagnosis but suffers from substantial inter-observer variability in Breast Imaging Reporting and Data System (BI-RADS) assessment, and existing deep learning models remain opaque. Multimodal large language models promise interpretabl...

Exercise, Glucose and Lactate Metabolism in Mild Cognitive Impairment: A Narrative Review

Mild cognitive impairment (MCI) is associated with cerebral glucose hypometabolism and an increased risk of progression to Alzheimer’s disease (AD). Altered lactate metabolism may represent an additional component of this metabolic vulnerability. We propose the Dual-Fuel Hypothes...

Incidental intestinal parasitic infections detected during colonoscopy: A case series of hookworm in a Cambodian immigrant and whipworm in Korean patients

Intestinal helminth infections have become uncommon in Korea but still occur sporadically, either as residual native infections or as imported infections among immigrants. We retrospectively reviewed 4 cases of intestinal helminth infections incidentally identified during colonos...

Development and Validation of Human-AI Collaborative Workflow in SNOMED CT Mapping of Bilingual Clinical Text

Abstract Systematized Nomenclature of Medicine–Clinical Terminology (SNOMED CT) is the principal international standard for semantic interoperability of clinical information, but mapping free-text clinical narratives to SNOMED CT concepts remains labor-intensive. We developed a l...

Criteria-based probable REM sleep behaviour disorder and risk of Lewy body dementia: analyses of a memory clinic cohort and a community cohort

Abstract Background REM sleep behaviour disorder (RBD) is the strongest prodromal marker of alpha-synucleinopathies, but whether a brief questionnaire carries prognostic information for Lewy body dementia is unclear. We tested whether criteria-based probable RBD (pRBD)—a question...

Network Structure and Central Symptoms of Depression in Older Korean Adults: A Community-Based Analysis

Objective This study aimed to investigate the network structure of Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV)-defined depressive symptoms in a large, community-dwelling sample of older Korean adults, to better understand symptom interrelationsh...

North Atlantic chlorophyll blooms modulate European hydroclimate and terrestrial productivity

Marine and terrestrial ecosystems are usually treated as separate components of the global carbon cycle, and whether variability in ocean biology reaches plant growth on land has remained unclear. Here we show that phytoplankton blooms in the high-latitude North Atlantic are link...

Role of Mn3+/Mn4+ redox-coupled oxygen vacancy modulation in SnO2 nanoarchitectures for ultrasensitive acetone detection

Acetone (CH 3 COCH 3 ) is a ubiquitous volatile organic compound in industrial and laboratory settings; however, its high volatility and toxicity necessitate advanced monitoring to ensure human health and occupational safety. In this work, we report a highly sensitive and selecti...

Vascularized human skin assembloids model compartmental skin organization and immune responsiveness in vitro

Allergic skin diseases, including atopic and contact dermatitis, are prevalent inflammatory disorders imposing clinical and socioeconomic burdens. Their pathogenesis involves impaired barrier function, genetic susceptibility and immune dysregulation, yet mechanistic insights rema...

Precipitate phase selection and grain boundary morphology in Cu-Ni-Si-Mn alloys: A machine-learning interatomic potential study

Alloys inevitably contain interphase boundaries, whose energetics govern nucleation processes and precipitate morphology. In Cu-Ni-Si alloys, Mn addition markedly changes grain boundary (GB) precipitation behavior. While GB precipitation of stable Ni 2 Si in Mn-free alloys is ass...

2025 Korean Guidelines for Cardiopulmonary Resuscitation: Part 9. Neonatal resuscitation: a secondary publication

The 2025 Korean Guidelines for Cardiopulmonary Resuscitation provide updated, evidence-based recommendations to optimize the transition from intrauterine to extrauterine life. While approximately 85% of term newborns initiate spontaneous breathing independently, timely interventi...

Efficacy of popliteal plexus block for opioid sparing and pain management after lower extremity surgery: a meta-analysis

Background: Postoperative pain management often depends on opioids, despite the associated adverse effects. The popliteal plexus block (PPB) presents a promising technique to reduce opioid consumption in surgeries. Methods: This meta-analysis evaluates the effectiveness of PPB wh...

Acceptance of Organs From Deceased Donors: Results of a Global Survey.

Background: With <10% of transplantation needs being met, one contributing factor may be the potential subjectivity in transplant specialists' acceptance of organs. Such decisions, if influenced by knowledge and/or comfort gaps, warrant intervention. We assessed knowledge and com...

Growth performance and immune responses of pigs from nursery to grower-finisher phase following different PRRSV-2 vaccination strategies: Evidence supporting a prime-boost regimen under field conditions in Korea.

This study evaluated the efficacy of various vaccination strategies against porcine reproductive and respiratory syndrome virus type 2 (PRRSV-2) in terms of growth performance and immune responses under field conditions at a commercial swine farm in Korea. A total of 80 pigs was...