Institution
Seoul National University
Recent research
- BiologyOpen access
AlkylsuccinylatedBentonite–GelMA Hybrid Hydrogelsfor Enhanced Mechanics and Osteogenic Drug Delivery
Abstract Bentonite is an attractive inorganic material for biomedical applications owing to its biocompatibility and large surface area. Here, we report a straightforward yet effective alkylsuccinylation strategy to tailor the bentonite surface with hydrophobic functionalities. S...
- Engineering & Technology
Abstract In reinforced concrete walls with low aspect ratios and construction joints, shear-sliding is a critical failure mode under earthquake loading. In this study, a backbone curve model was developed to capture the nonlinear response of walls with shear-sliding failure mode....
- Biology
Plasma Metabolomes Identify Distinct Asthma Metabotypes: Findings From the COREA Cohort
BACKGROUND: Phenotype-based asthma classification has limitations that have motivated endotype-based approaches grounded in pathophysiology. However, existing biomarkers offer limited specificity and clinical accessibility. Plasma metabolomics, which reflects disease-specific met...
- Materials & Energy
Abstract A series of bottlebrush polymers was rationally synthesized using norbornene-functionalized polylactide (NB-PLA), polycaprolactone (NB-PCL), and quaternized poly(2-(dimethylamino)ethyl methacrylate (NB-QPDM) via ring-opening metathesis polymerization (ROMP). These polyme...
- Health & MedicineOpen access
Abstract We evaluated the accuracy of a ring-type cuffless BP device (CART BP Pro) in detecting awake–asleep BP changes compared to conventional 24-h ambulatory BP monitoring (ABPM), following the validation protocol recommended by the European Society of Hypertension (ESH). Amon...
- Materials & EnergyOpen access
Advanced electronic and defense systems require multifunctional films that combine electromagnetic interference (EMI) shielding and infrared (IR) stealth with mechanical robustness, high electrical conductivity, and low IR emissivity. Here, we report a mechanically strong and hig...
- Engineering & Technology
Abstract The solubility of copper(II) acetylacetonate [Cu(acac)2] in carbon dioxide (CO2) and CO2/acetonitrile mixtures was measured at 313.15, 333.15, and 353.15 K and pressures up to 200 bar using a static gravimetric method. Since Cu(acac)2 decomposes before melting, its criti...
- Health & MedicineOpen access
Hepatic steatosis is the defining imaging feature of metabolic dysfunction-associated steatotic liver disease (MASLD) and is detected on abdominal CT. Whether CT-defined MASLD and hepatic fat burden are associated with brain morphometric variation beyond cardiometabolic and CT-de...
- Society & Economics
ABSTRACT The majority of existing sustainability‐linked bonds and loans utilize a pricing‐based approach in order to link the terms of the financing to an issuer's environmental, social and governance (ESG) performance. However, from a governance perspective, such an approach suf...
- BiologyOpen access
Postmenopausal osteoporosis (PMOP) arises from a bone remodeling imbalance in which osteoclast-mediated resorption exceeds osteoblast-driven formation. However, current therapies primarily target osteoclasts without restoring osteoblast function, underscoring the need for mechani...
- Health & MedicineOpen access
OBJECTIVES: This study evaluated immunohistochemical profiles associated with guided bone regeneration (GBR) using collagen membranes with different thickness-related mechanical properties to characterize membrane-related biological responses during lateral bone augmentation. MET...
- Climate & EnvironmentOpen access
Abstract. Arctic mixed-phase clouds (MPCs) remain challenging to represent in atmospheric models, with bulk microphysics schemes typically biased toward either excessive glaciation or inadequate ice formation. This study evaluates the behavior of the Weather Research and Forecast...
- Society & EconomicsOpen access
This study examined the association between living alone, socioeconomic status, and mortality among community-dwelling older adults. We analyzed mortality outcomes among 3,771 participants aged ≥ 60 years enrolled in the Korean Longitudinal Study of Aging (KLoSA) beginning in 200...
- Engineering & TechnologyOpen access
Continued scaling of dynamic random-access memory (DRAM) capacitors demands simultaneous achievement of high capacitance density and extremely low leakage current at ever-decreasing physical thickness, making interfacial chemistry and defect control as critical as the choice of h...
- Health & MedicineOpen access
Abstract Background Perioperative corticosteroids, particularly dexamethasone, have become a widely adopted component of multimodal pain management in total knee arthroplasty (TKA). While clinical practice guidelines strongly recommend their use, detailed guidance on optimal dosi...
- BiologyOpen access
Morphological and Metabolic Changes During Callus-Based Shoot Regeneration in Chamaecyparis obtusa
Chamaecyparis obtusa is a valuable conifer species, prized for its high-quality timber and bioactive essential oils. However, commercial micropropagation is challenging due to its resistance to vegetative propagation. This study aimed to develop an efficient in vitro plant regene...
- Society & EconomicsOpen access
Mapping the Korean national R&D system: a capability-based network approach to actor heterogeneity
Abstract This study introduces a capability-based network framework for analyzing actor heterogeneity in the Korean national R&D system. Using project-level data from the National Science and Technology Information System (NTIS)—comprising 63,305 R&D projects conducted by...
- BiologyOpen access
Major depressive disorder (MDD) remains a critical global health burden, and a substantial proportion of patients exhibit insufficient responses to conventional monoaminergic antidepressants. Selective inhibition of the two-pore domain potassium channel TREK1 has emerged as a pro...