Samsung Medical Center

Medical conflicts and their effect on Korean liver-related publications: A 2019–2024 analysis

Background: Concerns have arisen about a potential decline in Korean liver-related research output in 2024, possibly attributable to recent and severe medical conflicts.We investigated whether liver-related publication rates in Korea, particularly in the capital versus non-capita...

Anatomical patterns and sequence of distant metastasis in myxoid liposarcoma: a Korean single-center retrospective cohort study

Myxoid liposarcoma (MLS) is a distinct soft tissue sarcoma subtype with a predilection for extrapulmonary metastasis. Cohort data describing the metastatic pattern in Korean patients are limited, and the within-patient temporal sequence of pulmonary and extrapulmonary metastasis...

CT–measured diaphragmatic crus cross-sectional area and its association with short-term outcomes in acute exacerbations of COPD

Risk stratification for acute exacerbations of chronic obstructive pulmonary disease (AECOPD) in the emergency department (ED) is challenging. Conventional scoring systems, such as the Ottawa COPD Risk Scale (OCRS) and the Dyspnea, Eosinopenia, Consolidation, Acidemia, and Atrial...

Is Transanal Local Excision Oncologically Safe After Chemoradiotherapy? A Multicenter Phase II Study in ycT0–1 Rectal Cancer

PurposeTo evaluate the feasibility of local excision (LE) as an organ-preserving approach in patients with locally advanced rectal cancer showing a good response to neoadjuvant chemoradiotherapy (CRT). Materials and MethodsThis prospective, multicenter, single-arm phase II study...

Three-Year Outcomes of Drug-Eluting Stents, Drug-Coated Balloons, and Non-Drug-Eluting Devices in Native Femoropopliteal Artery Disease: An Analysis of the K-VIS ELLA Registry

Background: Although drug-eluting devices have demonstrated improved efficacy in femoropopliteal artery (FPA) disease, evidence on their long-term clinical outcomes in realworld practice remains limited.Methods: Using data from the multicenter Korean Vascular Intervention Society...

Depression as a Risk of Lung Cancer in Women: a Nationwide Cohort Study

BACKGROUND: Lung cancer is a leading contributor to global cancer incidence and mortality. While depression has been linked to adverse health behaviors, particularly tobacco smoking, that may elevate cancer risk, the direct relationship between depression and lung cancer remains...

Deep Learning-Assisted Segmentation, Multiparametric MRI Radiomics, and Clinical Features for Recurrence Risk Stratification in Young-Age Breast Cancer: A Prospective Pilot Study

Purpose: To develop an exploratory prognostic model integrating multiparametric MRI radiomics and clinical features for recurrence risk stratification in young-age breast cancer (YABC). Materials and Methods: In this prospective single-institution cohort, women under 40 years wit...

Gastric amphicrine carcinoma in the stomach: an unexpected presentation of MUTYH-associated polyposis

Amphicrine carcinomas of the stomach, defined by dual exocrine and neuroendocrine differentiation within the same neoplastic cell, are exceedingly rare. MUTYH-associated polyposis (MAP) is an autosomal recessive polyposis syndrome characterized by multiple colorectal adenomas and...

Predictors of Early Versus Late Atrial Tachyarrhythmia Recurrence After Cryoballoon Ablation by Atrial Fibrillation Type

ABSTRACT Introduction Patient characteristics and predictors of early (ERAT) and late (LRAT) recurrence of atrial tachyarrhythmia by atrial fibrillation (AF) type after cryoballoon ablation (CBA) remain poorly defined. Methods Using the Korean Heart Rhythm Cryoballoon Registry (1...

Effects of Body-Weight Changes on the Risk of New-Onset Diabetes in Individuals With Non-Diabetic Metabolic Dysfunction-Associated Steatotic Liver Disease

Background: Metabolic dysfunction-associated steatotic liver disease (MASLD) is associated with an increased risk of hepatic and extrahepatic complications.Although weight reduction is the primary recommended intervention, its impact on extrahepatic outcomes remains uncertain.We...

Association Between Artificial Sweetener Consumption and Bladder Cancer Risk: A Systematic Review and Meta-Analysis

Background:The potential association between artificial sweetener consumption and bladder cancer risk remains controversial.Therefore, we conducted a comprehensive metaanalysis synthesizing evidence from observational studies to elucidate this relationship.Methods: A systematic l...

Stereotactic body radiation therapy for hepatocellular carcinoma: 2026 expert consensus-based practical recommendation of the Korean Liver Cancer Association

Stereotactic body radiation therapy (SBRT) is a noninvasive, high-precision radiation technique that delivers a high dose to the tumor in a limited number of fractions, typically five or fewer, and is increasingly used as a curative-intent option for hepatocellular carcinoma (HCC...

Korean Clinical Practice Guidelines for Rehabilitation in Critically Ill Patients and Post-Intensive Care Syndrome

Background: Survivors of critical illness commonly experience persistent physical, cognitive, and psychological impairments, collectively known as post–intensive care syndrome. Although intensive care unit (ICU) rehabilitation is now recognized as an important part of recovery af...

Prognostic model for patients with oral cavity cancer using a novel multi-parameter index including radiation response of patient-derived tumoroids

Objective: No reliable model has been established to accurately predict the prognosis of patients with oral cavity cancer (OCC) following surgery and adjuvant radiation therapy. This study aimed to develop a tumoroid-based novel prognostic model for OCC to overcome the limitation...

Clinical experience in the treatment and prognosis of seven cases of Cronkhite-Canada syndrome

Cronkhite-Canada syndrome (CCS) is a rare, nonhereditary gastrointestinal polyposis syndrome. The rarity of CCS has led to a limited understanding of its optimal management and prognosis. We aimed to share our experience with 7 CCS patients, investigating the clinical characteris...

Application of Physiologically Based Pharmacokinetic Modeling to Optimize Assessment of Age‐Related Fluoxetine Accumulation in the Elderly

ABSTRACT This study quantified age‐related differences in fluoxetine pharmacokinetics and evaluated the influence of CYP2D6 phenotype using physiologically based pharmacokinetic (PBPK) modeling integrated with clinical therapeutic drug monitoring data. A PBPK model for fluoxetine...

P1.181. Comparison of the Da Vinci DV5 System With Force Feedback and the Xi Platform in Robotic Transthoracic Esophagectomy

Abstract Topic Esophageal Cancer: Surgical Treatment of Esophageal Cancer Background The da Vinci DV5 system incorporates integrated force feedback to enhance tissue handling and precision. By providing real-time tactile information, force feedback may reduce excessive traction a...

Clinical Application of Circulating Tumor DNA in Surgically Treated Esophageal Squamous Cell Carcinoma

Background: Esophageal squamous cell carcinoma (ESCC) is associated with a high recurrence rate and is one of the most aggressive malignancies. Recurrence is mainly detected via imaging modalities; however, postoperative imaging surveillance has disadvantages, including reduced s...

ChatGPT for pulmonary rehabilitation in chronic obstructive pulmonary disease is clinically credible but challenging for patients to use

Although interest in applying large language models (LLMs) in healthcare is rapidly growing, their role in supporting pulmonary rehabilitation (PR) for patients with chronic obstructive pulmonary disease (COPD) has not been well established. The primary objective of this study wa...

Identification of a Pathogenic RECQL4 1.6-kb Deletion–Insertion in a Neonate with Atypical Skeletal Phenotype of Baller–Gerold Syndrome Using Rapid Whole-Genome Sequencing

Mi-Ae Jang, M.D., Ph.D., Ja-Hyun Jang, M.D., Ph.D., Jin Kyu Kim, M.D., Ph.D., Joonhong Park, M.D., Ph.D., Go Hun Seo, M.D., Ph.D., Misun Yang, M.D., Ph.D., Yun Sil Chang, M.D., Ph.D., and Hyun Ho Kim, M.D., Ph.D.. Ann Lab Med -0001;0:. https://doi.org/10.3343/alm.2026.0102