Queen's University

Identification, validation, and prediction of longitudinal recovery phenotypes in degenerative cervical myelopathy: analysis of prospective cohorts and a randomised controlled trial

Background Symptom evolution in degenerative cervical myelopathy (DCM) is traditionally characterized by severity of neurological deficit. A recent expert consensus challenged this view, proposing that DCM fluctuates across neurological, functional and health-related quality of l...

Med-TDA: Medical Imaging Topological Data Analysis Tool

<ns5:p>Background Topological data analysis (TDA) has gained interest in medical image analysis, but there are no standardized definitions or pipelines to benchmark model performance. Current TDA tools and packages are mainly developed for general machine learning applications, t...

Lights, camera, coopetition: film and television production in a peripheral region

While ‘coopetition’ – the simultaneous competition and cooperation of firms in regional clusters – supports regional value creation, its dynamics in peripheral regions remain underexplored. This research addresses this gap by examining the antecedents of coopetition in the film a...

Generative AI for Hospital Cybersecurity: A Framework for Evaluating Large Language Models for Planning, Threat Detection, and Incident Response

The increasing digitization of healthcare records and growing reliance on interconnected systems have increased hospitals’ exposure to cyber threats, including ransomware, brute-force attacks, and Structured Query Language (SQL) injection. Traditional cybersecurity approaches alo...

Global Prevalence of Keratoconus in the Adult Population: A Systematic Review

To synthesize contemporary estimates of adult keratoconus prevalence worldwide and determine how geography, demographics, and study methodology shape reported rates. We systematically reviewed original studies (2019–2024) quantifying keratoconus in adults. We excluded paediatric-...

Correlated insulator Moiré bolometer

Light incident on an insulator is generally not expected to turn it into a metal without invoking intense ultrafast excitation that leads to transient structural transitions. Here we show that magic-angle twisted bilayer graphene tuned to half filling of the moiré band provides a...

Fostering engagement with accreditation: capitalizing on leaders’ professional values

Fostering educational leaders’ engagement with accreditation is important for the development of a Continuous Quality Improvement (CQI) culture in education programs, sustaining the quality of the education provided. Key to faculty engagement with academic demands is congruence b...

Terminology for describing the 24-h cycle of physical activity, sedentary behaviour, and sleep: a scoping review

Abstract Background Physical activity, sedentary behaviour, and sleep are three behaviours which occupy the 24-h cycle and interact to influence a multitude of health outcomes. Different terms are currently used to describe these behaviours collectively (e.g., movement behaviours...

The Zooplankton International Geospatial dataset: A global repository of spatiotemporal freshwater zooplankton community composition data from lakes and reservoirs to support ecological research

Abstract Zooplankton transfer substantial energy in aquatic food webs and are used as indicators of environmental change. Syntheses of zooplankton community dynamics globally require datasets that span a wide range of environmental gradients; however, these datasets are limited d...

The diagnosis to surgery interval and overall survival in patients with cervical cancer

Importance Evidence regarding the association of the diagnosis to treatment interval (DTI) and survival can inform clinical care and health policy. Data in this regard are currently lacking for cervical cancer. Objective To examine the relationship between the DTI and overall sur...

Geochemical and Isotopic Constraints on the Origin of the Early Palaeozoic Chah‐Nar Pb–Zn Deposit, Sanandaj–Sirjan Zone (Iran)

ABSTRACT The Chah‐Nar Pb–Zn deposit in the southern Sanandaj–Sirjan Zone, Iran, represents Early Palaeozoic stratiform sulfide mineralization hosted by organic‐rich volcano‐sedimentary rocks deposited in a Proto‐Tethyan back‐arc basin. Despite the occurrence of stratiform Pb–Zn m...

Fertility incentives in Canada: Period and cohort perspectives

Abstract We study the fertility effects of the 1997 Quebec Family Policy using two complementary approaches: (i) a period‐based repeated cross‐sectional analysis that examines the impact on period fertility (i.e., fertility rates in a given calendar year, such as births per 1,000...

A Novel Approach to Characterizing Patterns of Real-World Upper-Extremity Use During Walking and Activities of Daily Living in People with Subacute Stroke

In accelerometer-based measurement, the inclusion of upper extremity (UE) activity during walking can overestimate real-world functional UE use in people post-stroke. This study introduces a comprehensive, accelerometer-based approach to examining real-world UE use, including the...

Brentuximab Vedotin in Severe Systemic Sclerosis: Data on Long-Term Follow-Up and Retreatment

Objectives We previously reported skin and forced vital capacity (FVC) improvements in an open-label clinical trial exploring the use of brentuximab vedotin (BV) in patients with severe diffuse cutaneous systemic sclerosis (dcSSc).[1] Long-term outcomes after therapy was disconti...

Patient Perspectives on the Environmental Impact of their Advanced Therapy Injection Device

Objectives Data demonstrates there is a significant environmental impact using medications requiring injection, including the injecting device and needle. Rheumatology patient perspectives on this impact have not been previously explored. As part of a larger study, we aim to repo...

Patient Perspectives on Industry Sponsored Patient Support Programs for Advanced Therapy in Rheumatology

Objectives Industry sponsored rheumatology patient support programs (PSPs) for advanced therapies (ATs) are commonplace. While there is limited data to demonstrate their effectiveness in patient care, patient perspectives are even more lacking. This study aims to report patient v...

Common thought patterns reflect generosity, fairness, and social context

Abstract Humans generate thousands of thoughts each day, many of which concern other people. Yet it remains unclear whether these ongoing thoughts vary systematically across social contexts that demand meaningful social behavior, and whether they reflect individual differences in...