Philipps University of Marburg

Psychotherapy remission prediction models show limited cross-clinic generalizability in routine outpatient care

Abstract Clinical prediction models for psychotherapy outcomes have the potential to assist therapists in planning a patient’s individual treatment, but their clinical utility depends on maintaining predictive performance across settings. We assessed prediction of post-treatment...

Experiential avoidance as an early mechanism of an online mindfulness-based intervention for emotional distress: evidence from a behavioral paradigm in a randomized controlled trial

Given the substantial burden of global emotional distress and the proven efficacy of mindfulness-based interventions (MBIs), identifying early mechanisms of MBIs is critical for optimizing treatment adherence and outcomes. This study employed behavioral measures to investigate ex...

Glaciers and low-DOC ecosystems as sites of microbial carbon production and consumption

Abstract Glacier-fed waters are commonly viewed as heterotrophic ecosystems fuelled by highly bioavailable dissolved organic carbon (DOC), yet this paradigm is largely based on melt-season observations and assumes that microbial DOC dynamics are dominated by consumption. We show...

Intermolecular Carbon–Carbon Naphthalene Coupling Involves a Radical Mechanism Driven by Cytochrome P450 in Alternaria alternata

ABSTRACT Dihydroxynaphthalene (DHN) derivatives are precursors of biologically important molecules, including melanin and perylenequinones (PQs). Biosynthesis of DHN‐derived metabolites requires precise spatial control of radical reactions to form specific C─C or C─O─C bonds. Inv...

Local and Systemic Risk Factors of Dental Biofilm‐Induced Gingivitis and Their Control: A Systematic Review

ABSTRACT Objectives To identify local and systemic risk factors/indicators for dental biofilm‐induced gingivitis (DB‐GI) and to summarize evidence for their control. Methods A systematic review was undertaken following Preferred Reporting Items for Systematic Review and Meta‐Anal...

Violence and Happiness in Nigeria

Despite the prevalence of violence in Nigeria, large-scale empirical research examining its relationship with psychological well-being remains limited. This study addresses that gap using data from the World Values Survey (WVS). Violence is operationalised through two indicators:...

Cyclosporin A triggers a RIG-I-mediated interferon response through multiple cellular processes

Abstract The development of broad-spectrum antiviral agents is essential for preparedness against emerging viruses with pandemic potential. Cyclosporin A (CsA), a clinically approved immunosuppressant, has been shown to exert antiviral activity against a wide range of viruses. Re...

Development and preliminary evaluation of a German questionnaire assessing attitudes toward hearing aids and behavioral intention

Abstract Background Hearing aid uptake remains suboptimal despite well-established clinical benefits, suggesting that psychosocial factors influence hearing rehabilitation decisions. This study aimed to develop and perform a preliminary psychometric evaluation of a German-languag...

Divergent c-MYC Expression Patterns in NET and NEC: Insights from a Multicentre Cohort of 1380 Neuroendocrine Neoplasms

Abstract Neuroendocrine neoplasms (NEN) comprise well-differentiated neuroendocrine tumours (NET) and neuroendocrine carcinomas (NEC), whose distinction is clinically critical. Although c-MYC alterations have been implicated in NEC pathogenesis, c-MYC expression across NEC subtyp...

A pathway towards decentralized studies of radioactive post-lead elements and their applications in beyond standard model physics

Abstract Molecules have proven to be sensitive tools for studying physics beyond the Standard Model, with heavy and deformed nuclei offering decisive sensitivity to parity- and time-reversal-violating effects. However, almost all elements beyond lead, occupying the 6p to 5f atomi...

The Integrated Spatial Ecological Risk Assessment of Heavy-Metal Contamination in Arid Mining-Influenced Region in Central Asia

The spatial distributions of the potential ecological risk index (RI) and the geoaccumulation index (Igeo) in soils of the Zhetysu region (Kazakhstan) were examined. The enrichment factor ranged from 39.4 for cadmium to 21,481 for nickel. There are few non-ferrous metal enterpris...

Response diversity increases functional but decreases compositional stability of grassland communities

Summary The insurance hypothesis of biodiversity assumes that biodiversity increases ecosystem stability when functionally redundant species exhibit distinct responses to environmental changes, allowing some species to compensate for the loss of others. However, empirical evidenc...

Clinical outcomes and toxicity of electron-based intraoperative radiotherapy for partial breast irradiation: a single-institution experience

Purpose: Partial breast irradiation (PBI) using intraoperative electron radiotherapy (IOeRT) represents an attractive alternative to whole-breast irradiation in carefully selected patients with early breast cancer. Materials and Methods: Eighty-nine patients treated with single-d...

Machine learning analysis of COVID-19 transmission dynamics demographic risk and contact tracing outcomes in Nigeria

Abstract The COVID-19 pandemic has posed significant challenges to developing countries like Nigeria due to limited resources. Accurate prediction of disease spread is crucial for effective containment measures. This study investigates the application of statistical and machine l...

Social information quality and environmental volatility shape collective foraging behaviour

Abstract Collective foraging is widespread across the animal kingdom, allowing animals to more effectively discover resources. However, collective foragers need to balance a key trade-off between private exploration and using social information. Social information can come in ver...

Fulminant Fusobacterium necrophorum Meningoencephalitis Secondary to Frontal Sinusitis in a Previously Healthy Young Adult: A Case Report

Background: Fusobacterium necrophorum is an anaerobic Gram-negative organism classically associated with severe head and neck infections and Lemierre syndrome. Central nervous system involvement is uncommon but may be rapidly progressive and fatal, particularly when associated wi...

How many bromeliads are there? History and future perspectives of species scientific discovery in the pineapple family

Societal Impact Statement It remains unclear how many plant species are not yet recorded by science. We illustrated the process by which species of the pineapple family in tropical America have been newly described to science to date, and we estimated how many species may still a...

Functional mapping and engineering of the Sec translocon unlocked by a cell-free system

Abstract Almost all proteins are inserted or translocated across membranes by the universally conserved Sec translocon. Despite its central role, experimental access to Sec function has remained limited. Here, we present a cell-free protein synthesis platform that inserts SecYEG...

„Cohabitat Stadt“

Abstract Franziska Klose fotografiert die Habitate urbaner Pflanzen. Der Beitrag analysiert ihre Ausstellung „Cohabitat Stadt“ in der Galerie Ursula Walter in Dresden vom November 2025 bis Januar 2026 als eine Konstellation, in der die Bedeutung der Fotografien erst aus ihrem Zus...

Alles Unter Einem Dach

Abstract Im Jahr 2015 beschlossen Bund und Wissenschaftsrat die Förderung der Errichtung eines Forschungsbaus für das Deutsche Dokumentationszentrum für Kunstgeschichte – Bildarchiv Foto Marburg (DDK). 2025 konnte das Gebäude bezogen werden. Der folgende Text berichtet über die V...