Peking University

Tunnel field-effect transistors exhibiting performance beyond the Boltzmann thermionic limit

The International Roadmap for Devices and Systems (IRDS) has identified the tunnel field-effect transistor (TFET) as the most promising next-generation logic device that enables sustainable downscaling in driving voltage and power consumption. Demonstrating an acceptable sub–Bolt...

Sintering Behavior and Environmental Safety of Ceramsites Prepared from High-Alumina Fly Ash, Coal Gangue and Waste Glass

High-alumina fly ash and coal gangue were used as the main aluminosilicate precursors, and waste glass was introduced as a fluxing additive to prepare waste-derived ceramsites. Based on composition design assisted by the CaO-SiO2-Al2O3-Na2O phase diagram, the effects of sintering...

Quantum entanglement between gauge boson pairs at a muon collider

Abstract Quantum entanglement is one of the significant physics phenomena that can be examined in high energy collision . A muon collider can provide a stage on which we can study substantial physics phenomenon, starting from the precision measurements of the Standard Model and b...

A phase III clinical trial of PXT3003 in Chinese patients with Charcot-Marie-Tooth disease type 1A

Charcot-Marie-Tooth disease type 1A (CMT1A) is the most common inherited peripheral neuropathy and currently lacks disease-modifying therapy. PXT3003, a low-dose oral combination targeting PMP22 overexpression, has shown efficacy in two trials, while one recent confirmatory trial...

Modeling the potential impact of storage on the US power sector in a multisector dynamic context

The electric power sector is expected to grow in size, importance, and complexity around the world as economies expand and electric supply technologies and demand patterns evolve in significant ways. Newer, rapidly growing sectors could alter the temporal profile of electricity d...

Longitudinal alignments and syntheses of multimodal clinical data for personalized medicine with the PULSE framework

Multimodal models capable of imputing diverse data used in single-cell biology studies provide potential foundational opportunities in clinical practice. However, patient data uniquely comprise longitudinal mosaic measurements that reflect underlying physiological dynamics and ex...

Synergistic antitumor immune activation in melanoma using LA-PegPI polymeric gene vaccine in conjunction with PD-1 inhibition

Cancer gene vaccines are a promising avenue for cancer immunotherapy; however, their success depends not only on the gene construct itself but more critically on the efficacy and safety of the gene delivery vehicle. Targeting dendritic cells (DCs), the specialized antigen-present...

A Ballot-Word Formula for q-Zeta Numerators of Type-B Root Posets

We determine the Chapoton q-Zeta numerator for the full positive-root poset of standard Lie type B_r, graded by root height minus one and normalized with Chapoton's fixed denominator convention. For every standard Lie rank r >= 1, we identify the root poset with a trapezoidal cel...

Dynamic topological exciton-polaritons enabling ultrafast logic operations

Topological active materials have emerged as a powerful paradigm bridging the discovery of exotic topological phases of matter with the development of functional topological devices. The recent extension of these material systems into dynamic regime, where topological properties...

NICE: A Two‐Step Non‐Invasive Framework for Embryo cfDNA Read Enrichment and Quality Assessment

Non-invasive preimplantation genetic testing (niPGT) using cell-free DNA (cfDNA) extracted from spent embryo culture medium (SECM) has shown great potential, providing economic and practical advantages for embryo ploidy testing and quality assessment, while minimizing the risk of...

A Local Block Criterion for Periodic Morse Reductions of Circulant Independence Complexes

For G_n = Cay(Z/nZ, {±2, ±3}), we determine the homotopy type of its independence complex for every n ≥ 6. If n = 8q + r, the answer is a wedge of five (2q − 1)-spheres for r = 0, one (2q − 1)-sphere for r = 1, 2, 3, three 2q-spheres for r = 4, and one (2q + 1)-sphere for r = 5,...

Long-term oncologic outcomes following endoscopic versus surgical resection for GISTs: a propensity score matching analysis in the SEER database

Gastrointestinal stromal tumors (GISTs) are common tumors of the gastrointestinal tract. Endoscopic resection offers minimally invasive advantages, but its long-term outcomes versus surgery remain unclear. This study aims to evaluate the survival outcomes of endoscopic versus sur...

A Novel Role of DELTEX2 in Maintaining Genomic Stability of Granulosa Cells During Ovarian Aging

ABSTRACT Genomic instability is a key driver of ovarian aging, impairing granulosa cell (GC) function and diminishing ovarian reserve. However, the regulatory mechanisms underlying GC genomic homeostasis remain poorly defined. This study investigates the novel role of DELTEX2 (DT...

ClarifySTL: An Interactive LLM Agent Framework for STL Transformation through Requirements Clarification

Signal Temporal Logic (STL) is a formal language for specifying real-time behaviors of cyber-physical systems (CPS). Automatically transforming natural language requirements into STL specifications has received growing attention. Recent efforts leveraging large language models (L...

Digital Infrastructure and Agricultural Total Factor Productivity: A New Structural Economics Perspective on the “Broadband China” Policy

This study investigates the impact of the “Broadband China” pilot policy on agricultural total factor productivity (TFP) from a new structural economics (NSE) perspective. Using panel data from 297 Chinese cities (2000–2024), we employ a spatial difference-in-differences (SDiD) a...

A Randomized Placebo-Controlled Trial of HTD1801 Monotherapy in Participants With Type 2 Diabetes

OBJECTIVE: The safety and efficacy of HTD1801 versus placebo were evaluated in participants with type 2 diabetes inadequately controlled with diet and exercise. RESEARCH DESIGN AND METHODS: Key entry criteria of this phase 3, randomized, placebo-controlled trial included type 2 d...

Bridging the gap: neuroinflammation and the dawn of precision medicine in amyotrophic lateral sclerosis

Abstract Neuroinflammation is no longer a secondary feature of amyotrophic lateral sclerosis (ALS), but rather a disease-modifying process that actively shapes the motor neuron vulnerability from the earliest stages of pathology. Central and peripheral immune cells, including mic...

Hyperplane graph models for cotangent cohomology and quadratic obstructions of matroids

Let $M$ be a finite matroid and let $T^i(M)$ denote the cotangent cohomology of its Stanley--Reisner ring over a field. The paper gives a uniform hyperplane-graph model for every multigraded component of $T^2(M)$ and derives a characteristic-independent fine Hilbert series. It pr...

Environmental Misconduct and Legitimacy Repair: Evidence From Targeted Poverty Alleviation Campaigns in China

ABSTRACT Environmental administrative penalties not only impose regulatory and economic costs on firms but also threaten their legitimacy by undermining stakeholders' perceptions of their responsibility and reliability. Based on legitimacy theory, these legitimacy threats may mot...

An Essential Role of the AMPK-Related Kinase Snrk in Regulating Drosophila Sleep

Abstract Protein kinases are important regulators of sleep in animals, but their loss-of-function mutations usually show moderate phenotypes. We report here that sucrose non-fermenting related kinase (Snrk), a member of the AMP-activated protein kinase-related kinase (ARK) family...