Northeast Agricultural University

Natural Polysaccharides for Rheumatoid Arthritis Therapy: Mechanism, Drug Delivery and Clinical Application

ABSTRACT Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized primarily by chronic synovitis. Clinically, RA manifests as joint pain, swelling, and functional impairment caused by persistent synovial inflammation. Additionally, RA can involve vital organs, inc...

How interannual hydrological variability governs thermal stratification and selective withdrawal efficacy: Insights from the lower Lancang River cascade reservoirs

Study region The cascade reservoirs in the lower Lancang River, southwestern China. Study focus Natural river ecosystems rely on specific thermal regimes, which are frequently disrupted by deep reservoirs releasing cold hypolimnetic water. This study investigated how interannual...

Genome-Wide Characterization of the ScLOR Gene Family in Wild Tomato Solanum lycopersicoides Reveals ScLOR16 as a Negative Regulator of Cold-and Drought-Stress Tolerance

The LOR (LURP-one related) gene family encodes proteins containing conserved LOR domains; however, its functions in plant abiotic stress responses remain largely unexplored. In this study, we systematically identified and characterized the LOR gene family in the stress-tolerant w...

Natural variation in SL6 determines fatty acid components and seed longevity in rice

Seed longevity (SL) is vital for ensuring food security worldwide. However, the genetic basis of SL has been scarcely documented. Here, we report the cloning of a major SL locus, qSL6 , encoding a fatty acyl-ACP thioesterase type B. SL6 is functionally conserved in regulating pal...

The Effect of Taurine on the Alkalinity Stress Resistance of Eriocheir sinensis

High alkalinity, a major stress in saline–alkaline water, often leads to oxidative damage and apoptosis. Taurine has been shown to enhance the tolerance of aquatic animals to environmental stress, but whether it can reduce toxicity of alkalinity on Chinese mitten crab (Eriocheir...

Climatic Correlates of Brucellosis Transmission in a Semi-Arid Region of Xinjiang, China, 2015–2025: A Maximum Entropy Modeling Study Within a One Health Framework

More than 80% of global brucellosis cases occur in semi-arid regions; however, the climatic factors associated with these outbreaks remain poorly understood. This study investigated environmental correlates of brucellosis in a semi-arid region of Xinjiang, China. A maximum entrop...

Genome-Wide Identification of the Soybean GH5 Gene Family and Functional Analysis of GmGH5-22 in Salt Tolerance

Plant GH5 family genes function in both cell wall biosynthesis and stress responses. However, comprehensive studies on GH5 genes in the soybean remain limited. Here, we identified 28 GmGH5 genes from the soybean genome. Phylogenetic analysis assigned these genes to three subfamil...

A reinforcement learning framework with adaptive psychological state awareness for safe and effective intelligent psychological intervention

Intelligent psychological intervention systems require accurate perception of latent emotional states and the formulation of safe long-term strategies, which poses significant challenges to the non-stationary adaptability of learning algorithms. However, most existing approaches...

Evaluating Crop Yield Sensitivity to Climate Change Using a Deep‐Learning Framework Incorporating Vegetation and Groundwater Memory

Abstract Crop yields integrate contemporaneous weather and lagged vegetation and subsurface water states that reflect eco‐hydrological memory. However, these controls are observed only during the satellite era, creating a temporal mismatch between multi‐decadal crop‐yield records...

Single‐Cell Transcriptomics Reveals the FA9 – VAP Module Regulating Fatty Acid Accumulation in Soybean Seeds

ABSTRACT As a major commercial legume crop, soybean ranks among the world's most significant sources of edible oil and plant protein. We previously identified a SEIPIN homologue ( FA9 ) at the fatty acid 9 locus that promotes fatty acid accumulation in soybean. To examine the det...

Recent advances in fabrication strategies, functional modulation and healthcare applications of native protein-based hydrogels

Native protein-based hydrogels not only possess all advantages of their denatured analogues such as exceptional biocompatibility and low toxicity, but also retain the intrinsic function of the protein building block. Therefore, they exhibit novel favorable properties including in...

Evaluation of the structure and function of whey protein concentrate combined with folic acid and l ‐ascorbyl 6‐palmitate

Abstract BACKGROUND Whey protein concentrate 80 (WPC80) represents a highly promising carrier for bioactive compounds; however, the structural and functional consequences resulting from its noncovalent interactions with folic acid (FA) and l ‐ascorbic acid 6‐palmitate (LAP) remai...

Study and application of the profile-attenuation-based standardized soil moisture index

Cold-region spring crops are highly sensitive to water stress during the seedling stage, making spring agricultural drought a major constraint on crop productivity in semi-arid regions. Conventional drought monitoring often relies on the Standardized Soil Moisture Index (SSMI), w...

Multi-Algorithm Hierarchical Minimum Data Sets for Soil Quality Assessment in the Black Soil Region of Northeast China: A Case Study in Keshan County

The Northeast black soil region is a major grain-producing area in China, where county-scale assessment of topsoil quality is essential for soil conservation and provides a potential indicator framework for regional soil quality monitoring. In this study, 500 composite cultivated...

Regulation of Egg Quality by Methionine Selenium: Physicochemical and Structural Characteristics of EggShell, Egg Yolk, and Egg White

Selenium is an essential trace element in the body, and supplementing it in production can improve egg quality. Sixty healthy 48-week-old Hy-Line Brown laying hens were randomly assigned to two groups. In this study, the effects of dietary selenomethionine (SeMet) supplementation...

Biological and metabolism responses of earthworm (Eisenia fetida) exposed to metribuzin

Metribuzin, a widely used triazine herbicide, has been extensively studied for its toxic effects on aquatic organisms, but its impact on soil organisms, particularly earthworms, remains insufficiently understood. This study investigates the ecological toxicity of metribuzin on Ei...

Lycopene AttenuatesDEHP-Induced Cerebral Injury bySuppressing cGAS-STING-Mediated Microglial Activation

Abstract Di(2-ethylhexyl) phthalate (DEHP) is a widespread environmental pollutant with neurotoxicity, while lycopene (LYC) is a neuroprotective dietary carotenoid. This study investigated whether LYC alleviates DEHP-induced brain injury by regulating microglial activation and cG...

Ketogenic diet induces cardiac changes via the OHB-Ffar3-Hopx/ACTC1 regulatory pathway in growing mice

The ketogenic diet (KD), a high-fat, low-carbohydrate dietary regimen widely used for drug-resistant epilepsy and weight management, has been increasingly applied in adolescents. However, its long-term effects on juvenile cardiac development and functional homeostasis remain poor...

Effects of Fermented Palm Kernel Meal on Lactation Performance, Rumen Fermentation, Rumen Microbiota, and Rumen Metabolomic Profiles in Holstein Dairy Cows

This study evaluated the impact of fermented palm kernel meal (FPKM) on the lactation performance, blood biochemical indices, rumen microbiota, and metabolic functions of Holstein dairy cows, aiming to enhance the nutritional value of palm kernel meal (PKM) through solid-state fe...