Newcastle University

Grey is the new black: entrepreneurial agency and transparency of artificial intelligence

Purpose This paper develops the MIRACLE framework, a stage-based conceptual model that examines how human and artificial cognitive agents interact across the entrepreneurial process, how artificial intelligence (AI) transparency affects entrepreneurial agency and how heterogeneou...

Aggregation framework for continuous digital health measures and application to walking activity data

Abstract No standardized procedures for aggregating continuous digital health measures exist. Using a modified Delphi approach, we developed a framework to standardize the selection of aggregations that provide clinically meaningful, stable values. This was applied to aggregate s...

Capability-driven international scale-up: the moderating role of co-creation and technology

Purpose This paper investigates how small and medium-sized enterprises (SMEs) in resource-constrained regions build international scale-up intentions and convert them into internationalization performance. Drawing on a dynamic capabilities perspective, the study examines how capa...

Can discussions with patients and the public clarify missing data mechanisms for digital outcome measures?

Abstract Background Analysis of clinical trials with missing data requires statistical assumptions. When novel digital outcome measures are used, it is particularly important to understand trial participants’ experiences with the device. This can illuminate the reasons for and sp...

Co‐Designing a Prototype Education and Training Intervention for Healthcare Professionals Working in Community Laryngectomy Care: An Experience‐Based Co‐Design Study

INTRODUCTION: Evidence indicates that people with a laryngectomy often perceive community healthcare professionals as less knowledgeable than hospital-based clinicians. Some individuals also report feeling more skilled than the professionals supporting them at home. This highligh...

The Rare dISease Evaluation (RISE) study: a survey-based investigation of medical student experience and knowledge of rare disease in the UK

Abstract Background Rare diseases are a significant public health concern, with over 6,000 diseases identified with an estimated collective point prevalence of 5.6–6.9%. People living with rare disease face numerous challenges within healthcare including prolonged time to diagnos...

Why Metrics Matter in Thyroid Eye Disease

Importance Advances in the understanding of the pathophysiology of thyroid eye disease (TED) provide an opportunity to use novel, targeted therapeutic agents. However, our capacity to assess the efficacy and indications for the new agents is potentially limited by the clinical me...

The Implementation of Current UK Guidance for the Treatment of Co-Occurring Mental Health and Substance Use Conditions: A Mixed Methods Systematic Review and Thematic Synthesis

This review identified an implementation gap between best practice guidance and the provision of care for co-occurring conditions in the UK setting, which needs to be explored across a global context. There were positive examples of strategies to implement the guidance, particula...

Engaging in non‐work‐related information and communication technology activities for work recovery: A systematic literature review

Abstract This systematic literature review makes a theoretical contribution by separating the recovery process into two components: non‐work‐related information and communication technology (ICT) activities and recovery experiences. This distinction helps identify how different a...

Loss of galactan synthesis in pea (Pisum sativum) causes defects in organ expansion and is associated with increased extensin content

Abstract Pectic galactan is a rhamnogalacturonan-I side chain, composed of β-(1→4)-linked D-galactose residues. Its multifunctional role in cell wall assembly and properties has been proposed in various developmental contexts. In this study, we investigated the role of galactan i...

Impact of high temperatures on healthcare utilisation among older adults: a scoping review

Abstract Background Rapid global ageing coincides with rising temperatures and increasing strain on healthcare services. High temperatures are associated with increased healthcare demand, yet evidence on older people’s healthcare utilisation remains fragmented and is often servic...

Quality standards for preclinical research in cardio-oncology

Preclinical research in cancer therapy-related cardiovascular toxicity (CTR-CVT) is a major domain of cardio-oncology and has provided biological explanation for the cardiovascular adverse effects of many cancer therapies. However, the choice of the experimental models to investi...

Invited perspectives: Towards usable compound event research

Abstract. Supporting stakeholders with science-based decision-making to mitigate and adapt to climate change impacts is a central mandate of the climate research community. In particular, mapping out scenario-dependent climate risk landscapes is one of the most pressing challenge...

Exploring Transitions to Adulthood for Young Disabled People: Personalisation and the Quiet Dismantling of Social Care

ABSTRACT Across OECD countries, policy frameworks to support disabled young people in their transition to adulthood remain fragmented, under‐resourced and poorly aligned. This article examines how these longstanding weaknesses have been exacerbated by the shift towards personalis...

Neural signatures of altered adaptation to repetitive auditory stimulation in tinnitus

Abstract A growing body of studies has explored tinnitus within a predictive coding framework, proposing that predictive mechanisms may contribute to its development and persistence. However, many aspects of this relationship remain to be clarified. While mismatch negativity (MMN...

Cripping the Transition to Practice: A Longitudinal Qualitative Analysis of Disabled Doctors’ First Year Experiences

Abstract Introduction The transition from medical student to doctor is demanding. Although research has explored preparedness and wellbeing, disabled doctors’ experiences remain underexamined, risking a homogenised understanding of a process that is likely experienced unevenly ac...

Validation of Newcastle ENDOPREM for assessing patient experience with colonoscopy: a multicenter prospective study

Patient experience is a key quality indicator for colonoscopy, yet standardized assessment tools are lacking in China. The Newcastle ENDOPREM scale has shown promise internationally but requires validation in China. To translate, adapt, and preliminarily evaluate the psychometric...

Using Listening Rooms for Qualitative Data Collection in Medical Science Education Research

Abstract Listening Rooms are a qualitative data collection method, wherein two participants have a discussion without a researcher present. The conversation is guided by prompts provided by the researcher. This approach can elicit more candid, honest accounts of experiences than...

Rapid soil moisture depletion during flash droughts accelerates wildfire spread in the United States

Abstract Fire danger can escalate rapidly when vegetation dries over days to weeks. Flash droughts, characterised by rapid root-zone soil moisture depletion under high evaporative demand, may accelerate wildfire spread. Here, we quantify relationships between flash droughts and w...

Uncommon benign tumour of the scalp

A 37-year-old male (Fitzpatrick skin type III) presented with a 10-month history of an enlarging nodule on the right parietal scalp. There was a paternal history of melanoma, but no family history of similar skin lesions. Physical examination revealed an ill-defined, pink, round,...