Medical University of Lodz

Efficacy and tolerability of venetoclax plus rituximab in relapsed or refractory chronic lymphocytic leukemia – real-world analysis of Polish adult leukemia study group

We collected clinical data on 363 patients with relapsed/refractory chronic lymphocytic leukemia (RR-CLL) treated with venetoclax-rituximab (VR) in a real-world setting. The median age was 69.5 years (range, 32.5–91.6 years), and the median number of prior lines of therapy was 2...

Are Signal Peptides Hidden Regulators of Neurodegenerative Disease?

Canonical signal peptides (SPs) are short N-terminal sequences that direct nascent proteins into the secretory pathway, but their role extends far beyond protein targeting. Advances in sequencing and computational tools have enabled their systematic identification across proteome...

Advances in Nuclear Medicine Diagnostics: The Promise of Radiolabeled Dendrimers

One of the most widespread causes of mortality is cancer, and its early diagnosis is a key element of modern medicine. A crucial role is played by imaging techniques such as positron emission tomography (PET), single-photon emission computed tomography (SPECT), and computed tomog...

KSR2 is a novel oncogene in TAL1 subtype of T-cell acute lymphoblastic leukemia with potential clinical and prognostic implications - Supplementary Methods

Supplementary Materials and Methods for "KSR2 is a novel oncogene in TAL1 subtype of T-cell acute lymphoblastic leukemia with potential clinical and prognostic implications" accepted for publication in Haematologica (2026) The published article includes an abbreviated Methods sec...

KSR2 is a novel oncogene in TAL1 subtype of T-cell acute lymphoblastic leukemia with potential clinical and prognostic implications - Supplementary Methods

Supplementary Materials and Methods for "KSR2 is a novel oncogene in TAL1 subtype of T-cell acute lymphoblastic leukemia with potential clinical and prognostic implications" accepted for publication in Haematologica (2026) The published article includes an abbreviated Methods sec...

Vitamin D levels and other factors associated with depressive symptoms and cognitive impairment in the oldest-old patients with diabetes

The aim of the study was to determine the serum 25-hydroxvitamin D levels in patients aged over 85 years with type 2 diabetes and identify the factors (including vitamin D levels) associated with comorbid depressive symptoms and mild cognitive impairment (MCI). A group of 188 T2D...