Macau University of Science and Technology

LC−MS-Based Chlorine-Signature Query Engine Strategy for Automated Discovery of Phosphate-Containing Metabolites

Abstract Comprehensive profiling of phosphate-containing compounds (PCCs) in untargeted metabolomics remains challenging due to their high hydrophilicity, poor separation, and low stability, which hampers high-throughput screening from large-scale liquid chromatography−mass spect...

PCSK9 inhibitors usage in South China: A Multi-Center Real-World Study

Proprotein convertase subtilisin/kexin type 9 inhibitors (PCSK9i) are effective for lipid management in high-risk patients with atherosclerotic cardiovascular disease. Their inclusion in China’s National Reimbursement Drug List and the Hong Kong Hospital Authority Drug Formulary...

MCGMark: An Encodable and Robust Online Watermark for Tracing LLM-Generated Malicious Code

With the advent of large language models (LLMs), numerous software service providers are developing LLMs tailored for code generation, such as CodeLlama. However, these models can be exploited by malicious developers to generate malicious code, posing severe threats to the softwa...

Mogroside V attenuates inflammatory responses by modulating the miR-448-3p/ELL2/PDE4A axis in vitro

Various studies have revealed that natural compounds exert their bioactivities through regulation some miRNA expression. Our previous work demonstrated that Mogroside V (MV) exerts anti-inflammatory effects by downregulating miR-21-5p in LPS-stimulated RAW264.7 macrophages. Our m...

Selective Photoelectrochemical Water Oxidation to Hydrogen Peroxide via Tip-Induced Interfacial Regulation

Abstract Bicarbonate (HCO3–) electrolytes have significantly promoted photoelectrochemical water oxidation to H2O2 production over the competitive O2 evolution. However, the selectivity and efficiency are still fundamentally constrained by the limited solubility of the HCO3–, the...

Toward sustainable energy transition through green transport policy: Evidence from low-carbon transport system pilot

Sustainable energy transition is a crucial step toward sustainable development, yet little is known about how it can be achieved through the transport sector. Utilizing data from 2005–2019 for cities in China, this study investigates how low-carbon transport system pilots contrib...

Major adverse cardiac events and mortality associated with ADHD and its treatment in adults with type 2 diabetes: a multi-national cohort study

Abstract Background Attention-deficit/hyperactivity disorder (ADHD) has been linked to elevated risk of type 2 diabetes (T2D). However, the impact of ADHD and ADHD medication use on prognosis and health outcomes in T2D remains unclear. This study investigates the associations of...

Chronic carbonate alkalinity exposure impaired the mechanical properties of exoskeleton and the intestinal microbiota of juvenile Macrobrachium rosenbergii

Along with the global expansion of saline-alkali aquaculture, understanding the physiological adaptation of economically important species like Macrobrachium rosenbergii to alkaline stress is essential for sustainable aquaculture production. This study investigated the effects of...

Collecting probabilistic goods: a framework for sequential decision-making based on the Coupon Collector’s Problem

Abstract In this work, we investigate consumers’ sequential decision-making behavior under the setting of collection-based probabilistic selling. We formulate the sequential purchasing process as a draw-level Markov Decision Process (MDP) built on the classical Coupon Collector’s...

Electron Regulation of Proton Cyclotron Waves at Mars

Abstract Proton cyclotron waves (PCWs), generated by the solar wind ionization and subsequent pickup of exospheric hydrogen, offer independent constraints on water loss from Mars. However, translating wave observations into quantitative escape rates has been hindered by an incomp...

Driving destination image and advocacy through heritage rejuvenation experiences: a comparative study of postmodern and traditional tourists through Gaze Theory

This study centres on cultural heritage tourism as a pivotal driver of cultural transformation, investigating the influence of heritage rejuvenation experience quality on destination image and tourist advocacy behaviour. With the growing expansion of the postmodern tourist, their...

GHA-Agent: A Multi-Agent Framework for GitHub Actions Log Parsing

The advent of continuous integration and continuous deployment (CI/CD) technologies has significantly reduced development cycles for engineering teams. As the world's largest open-source repository, the GitHub Actions (GHA) platform has rapidly become the preferred tool for devel...

Public Perception and Optimization of Macau Light Rapid Transit’s Cultural Space from the Perspective of Social Media Data

Abstract As rail transit systems increasingly assume the function of disseminating urban culture, light rail cultural space has gradually become an important interface for citizens to perceive local characteristics and establish urban identity. As a tourist city where Chinese and...

Bond between alkali-activated repair mortars and OPC concrete substrate: Strength calculation, failure mode statistics and mechanisms

To assess the feasibility of using alkali-activated mortar as a repair material for existing damaged concrete, the interfacial bonding properties between alkali-activated slag/fly ash repair mortar and substrate concrete are systematically studied, focusing on the effects of slag...

Photoactivated Organic Gas-Sensing Synapses with Enhanced Response and Memory for Neuromorphic Olfactory Systems

Abstract High-performance olfactory synapses are critical for efficient, wide-dynamic-range, and low-power neuromorphic sensing. Organic semiconductor devices, which offer advantages such as room-temperature operation, biocompatibility, and potential for large-scale manufacturing...

Perioperative non-invasive neuromodulation for delirium and cognitive recovery: from preclinical evidence to clinical translation

Perioperative neurocognitive disorders (PND) are a challenge for patients to accelerate postoperative recovery, and exploring more effective interventions can help reduce long-term cognitive dysfunction. Non-invasive neuromodulation (NIN) has shown potential in improving postoper...

Structural Analysis of an Inulin-Type Fructan from Ophiopogon japonicus and Its Immunomodulatory Properties

A water-soluble, low-molecular-weight polysaccharide fraction, designated OJP-2, was extracted from the roots of Ophiopogon japonicus; its structural characteristics and immunomodulatory activity in macrophages were subsequently investigated. OJP-2 exhibited a narrow apparent mol...

Do CSR initiatives foster sustainable consumption? A cross-cultural meta-analytic structural equation modelling approach

Purpose This research investigates how corporate social responsibility (CSR) activities influence sustainable consumption behaviour, specifically whether they truly promote ethical consumerism or unwittingly legitimize overconsumption by superficial sustainability efforts. Design...

ALOX15-Inhibitory Peptides Derived from Coffee Bean Protein Hydrolysates Confer Neuroprotection against Lipid Peroxidation

Abstract Coffee beans are widely consumed worldwide and are known for their central nervous system-stimulating effects, mainly attributed to caffeine and other small molecules. However, the neuroprotective potential of coffee bean-derived peptides remains largely unexplored. In t...

A Biomimetic cascade nanoreactor enabled by tumor microenvironment remodeling for precise CO release and enhanced cu-mediated chemodynamic therapy

Prostate cancer (PCa) is the most prevalent malignant tumor in the male genitourinary system. Carbon monoxide (CO) gas therapy and chemodynamic therapy (CDT) have emerged as alternative treatments for cancer. However, the therapeutic efficacy of both approaches is constrained by...