Lund University

Temporal Association Between Intrathoracic Impedance and Tachyarrhythmia Occurrence

BACKGROUND: This study examined whether daily intrathoracic impedance is temporally associated with the occurrence of atrial fibrillation (AF) and ventricular tachycardia (VT). METHODS: This retrospective cohort study included 117 patients with cardiac implantable devices, follow...

4D reconstruction of alumina laser melt pools at 25 kHz via operando X-ray multi-projection imaging

Abstract Advancing additive manufacturing, e.g., laser powder-bed fusion (LPBF), requires resolving rapid processes such as melt-pool dynamics and keyhole evolution in 4D (3D + time). Operando X-ray tomography is a state-of-the-art approach for 4D characterization, but its tempor...

The Abundance of Phenylalanine in the DNAJB6b Linker Governs Its Role in Amyloid Suppression

Abstract The molecular chaperone DNAJB6b inhibits the disease-related self-assembly of amyloid peptides in an efficient and ATP-independent manner. The molecular basis for this action is not yet fully understood, but the low-complexity region of DNAJB6b as a stand-alone peptide d...

Plant functional type composition drives summer carbon cycling in an ombrotrophic peatland

Abstract Peatlands are globally important carbon sinks because plant CO 2 uptake outweighs microbial decomposition. These ecosystems are characterised by a distinct microtopography of hummocks and lawns, supporting vegetation communities composed of various plant functional types...

Laboring unruly technology: work, autonomous buses, and ambivalent expectations on the front lines

Automation constitutes a socio-technical project where expectations about the uncertain future of work are formed and negotiated. Rather than focusing on the expectations and imaginaries of elite groups, the spread of automation has made occupational futures a concern for many fr...

Insect outbreak progression over three years shapes biogenic volatile emissions in a mountain birch forest

Abstract Geometrid moth outbreaks are important natural disturbances in mountain birch ( Betula pubescens ssp. czerepanovii ) forests of northern Fennoscandia and are expected to intensify with climate change. Impacts of these outbreaks and moth herbivory on biogenic volatile org...

Highly resolved representations of dynamic haptic inputs in non-primary sensory cortical neuron representations

Abstract Recent studies suggest that the width and extent of cortical spread of sensory information appears to traditionally have been dramatically underestimated. Even neurons in primary visual cortex can carry detailed information about tactile inputs as shown in experiments us...

Death by a thousand papercuts: professionals’ imaginaries on ethicalization and technological determinism of AI in Sweden

Abstract While Sweden’s sociotechnical identity relies on a firm foundation of the welfare state and a frontrunner status, its artificial intelligence (AI) trajectory increasingly clashes with global market realities. Analyzing interviews with 13 professionals across the industri...

Network analysis of the genetic relationships between twenty psychiatric and substance use disorders.

We sought to clarify, using network analysis, the structure of genetic risk factors for a wide range of psychiatric and substance use disorders. Using split halves (N=1,510,974), we computed the family genetic risk scores (FGRSs) for 20 psychiatric and substance use disorders ass...

Passive sampling for grazer cues incorporates top-down effects in harmful algal bloom monitoring and toxin prediction

Domoic acid (DA) produced by toxigenic species of the diatom genus Pseudo-nitzschia during harmful algal blooms (HABs) bioaccumulates in filter feeders, bait fish, and commercial seafood products, posing a threat to marine organisms and public health. Copepodamides, a group of po...

MEGATRON: Reproducing the Diversity of High-Redshift Galaxy Spectra with Cosmological Radiation Hydrodynamics Simulations

We present the MEGATRON suite of cosmological radiation hydrodynamics simulations following the formation of Milky Way-mass galaxies from the earliest cosmic epochs when Population III stars form to Cosmic Noon. The suite represents the first set of cosmological simulations that...

MEGATRON: how the first stars can create an iron metallicity plateau in the smallest dwarf galaxies

We study the stellar mass-iron metallicity relation of dwarf galaxies in the new high-resolution MEGATRON cosmological radiation-hydrodynamics simulations. These simulations model galaxy formation up to z ≈ 8 in a region that will collapse into a Milky-Way-like galaxy at z = 0 ,...

Spatial Proteomics as a Potential Decision‐Support Layer for Early Melanoma: A Narrative Review

Distinguishing early melanoma from borderline, atypical, or biologically intermediate melanocytic lesions remains one of the most consequential and urgent diagnostic challenges in dermato-oncology, since melanoma causes nearly 95% of skin cancer deaths. This narrative review esta...

Multiscale transitional flow in anisotropic nanoparticle suspensions revealed by time-resolved X-ray scatter microscopy

Abstract Complex fluids transition from laminar to transitional flow above a critical control parameter, in a similar manner to their Newtonian counterparts. In a continuum mechanics sense, fluid elements follow the ensuing complex trajectories, which gives rise to secondary flow...

Data-Centric Solutions – A Case Study for Road Data Based on Knowledge Graphs

This study demonstrates how a data-centric architecture can be implemented with a knowledge graph based on generic datasets to enable a road maintenance tools. Two datasets were used: a 3D city model (CityGML/3CIM) and a national road database. Road polygons (CityGML/3CIM) were g...

Insulin Resistance in the 21st Century: New Takes on an Old Problem—2025 Diabetes , Diabetes Care , and Diabetologia Expert Forum

Insulin resistance is a hallmark of type 2 diabetes and several other metabolic diseases. However, efforts to improve insulin resistance are hindered by the biological complexity inherent to insulin action, as well as conceptual and methodological limitations to date. In Septembe...

Insulin resistance in the 21st century: new takes on an old problem—2025 Diabetes, Diabetes Care, and Diabetologia Expert Forum

Insulin resistance is a hallmark of type 2 diabetes and several other metabolic diseases. However, efforts to improve insulin resistance are hindered by the biological complexity inherent to insulin action, as well as conceptual and methodological limitations to date. In Septembe...

Cross-platform, multi-cohort identification of a caries microbial signature

Objective To identify a robust salivary microbial signature associated with caries using a cross-platform, multi-cohort design.Design Full-length 16S rRNA gene sequencing (ONT) and shotgun metagenomics (MET) were performed in a derivation cohort with matched data (n = 463). Assoc...

MEGATRON: the impact of non-equilibrium effects and local radiation fields on the circumgalactic medium at cosmic noon

We present three cosmological radiation-hydrodynamic zoom simulations of the progenitor of a Milky Way-mass galaxy from the MEGATRON suite. The simulations combine on-the-fly radiative transfer with a detailed non-equilibrium thermochemical network (81 ions and molecules), resolv...

Adverse early-life conditions and their impact on the marriage market and social mobility: The Poznań birth cohort, 1830–1855

Objectives Early-life conditions may influence later-life outcomes through biological scarring and selective survival mechanisms. However, the long-term effects of childhood adversity on marriage formation and social mobility remain insufficiently explored in historical populatio...