Lund University

Decreasing Trends in Birth Prevalence and Severity of Cerebral Palsy in Sweden During 2000–2019: A Population‐Based Registry Study

AIM: To examine temporal trends in cerebral palsy (CP) birth prevalence and changes in functional severity in Sweden between 2000 and 2019. METHODS: This population-based registry study included all children with CP born in Sweden between 2000 and 2019. Annual CP birth prevalence...

Improvement in peripheral airway function after a 12-week exercise intervention in COPD

Abstract Background Exercise is a cornerstone of chronic obstructive pulmonary disease (COPD) management and improves quality of life, exercise capacity, exacerbation frequency and survival. However, the physiological mechanisms underlying these effects remain unclear. Small airw...

The chemical influence of flue gas recirculation in NH3-H2 MILD combustion: an experimental and kinetic investigation

Ammonia is a promising hydrogen carrier with potential in carbon-neutral energy systems. However, its combustion faces the challenges of high NO emissions and inadequate stability. Moderate or Intense Low-oxygen Dilution (MILD) combustion preheats NH 3 , promoting its cracking to...

Energy-efficient dynamic temperature control for frozen plant-based food transport using model predictive control

Abstract Refrigerated road transport is energy intensive because conventional controllers regulate compartment air temperature reactively while the cargo itself changes temperature slowly. In this work, the potential energy savings from shifting the control reference from air to...

Design Approaches for Oxygen Reduction Systems for Warehouse Storage Applications

ABSTRACT Oxygen reduction systems (ORS) are protection systems, with a design protection objective to limit fire spread beyond the point of ignition. Research has shown that the prescriptive design methods, in VdS 3527, EN 16750, and ISO 20338, are not appropriate as prescriptive...

Trajectories of physical activity following digital education and exercise therapy—a longitudinal registry study among 15,197 persons with knee or hip osteoarthritis

Abstract Objective This study examined trajectories of physical activity (PA) and associated factors among individuals with knee or hip osteoarthritis (OA) participating in a digital education and exercise therapy program. We additionally compared patterns of patient-reported out...

Predictors of improvement in personal recovery and activity engagement among mental health service users following a group-based sensory modulation intervention

BACKGROUND: Mental health service users often have sensory processing difficulties affecting activity engagement and personal recovery. Since interventions targeting this area are scarce, a group-based sensory modulation intervention was developed. To determine in which settings...

Early onset of the hot circumgalactic medium around Milky Way galaxies

Abstract Hot coronae are key regulators in Milky Way (MW)-type galaxy formation and are thought to emerge once a galaxy’s dark matter halo crosses a critical mass threshold, Mvir ~ 1012 M⊙, so that accretion shocks can heat infalling gas to virial temperatures, Tvir. Here we inve...

Toxicity Evaluation of Microplastics Exposure in Water Contaminated with Pyrene and Methyl Chlorpyrifos Using Daphnia magna

Abstract In freshwater environments, microplastics (MPs) have emerged as important organic contaminants vectors. This study investigates the individual and combined toxicity of microparticles of polystyrene (PS) and polylactic acid (PLA) with two contaminants of major concern in...

Obesity policy in Portugal: epidemiology, sociology and the limits of prevention

Abstract Obesity prevention has become a prominent public health priority in Portugal, yet policy responses continue to engage unevenly with the social conditions through which obesity is produced and distributed. This paper examines Portuguese obesity policy through an integrate...

Human factor H-related protein 5 modulates the classical and lectin complement pathways on selected host ligands

Abstract C4b-binding protein (C4BP) and factor H (FH) are the main soluble negative regulators of the classical/lectin (CP/LP) and alternative (AP) complement pathways, respectively. They do not only act in solution but also interact with host ligands such as C-reactive protein (...

Meeting lifestyle recommendations among cancer survivors – a cross-sectional descriptive analysis from the Swedish CArdioPulmonary BioImage study (SCAPIS)

PURPOSE: This study aimed to describe lifestyle patterns in relation to recommendations -including physical activity, diet, smoking, alcohol consumption, and sleep quality-among Swedish cancer survivors, stratified by sex and age. METHOD: A descriptive cross-sectional study was p...

Speculation Is Not Evidence: A Response to Conviction Is Not Commission

This response addresses a commentary by Orhan and Bal on our study of immigrant background and rape+ conviction in Sweden. We agree that conviction data do not capture all offending and that bias may occur at different stages of the criminal justice process. Our disagreement conc...

Socioeconomic status and longitudinal neurocognitive outcomes following childhood brain tumour diagnosis: a Swedish national population-based cohort study

Abstract Background Lower socioeconomic status (SES) is linked to poorer neurocognitive development in the general population, but these effects in paediatric brain tumour survivors are underexplored. We examined the relationship between parental SES, clinical factors, and neuroc...

Irreversible Silver Migration in Single CsPbBr3 Perovskite Nanowire Devices

Abstract Silver (Ag) has gained interest as an electrode material for metal halide perovskites due to its high electrical conductivity, low cost, and simple deposition. The electromigration and interface redox-process of Ag has been exploited for electronic applications such as m...

Health utilities in individuals with alpha-1 antitrypsin deficiency with and without COPD from the EARCO registry

Background Data on health utilities in Alpha-1 antitrypsin deficiency (AATD) are scarce. This study aimed to evaluate health-related quality of life (HRQoL) using the EQ-5D in a cohort of AATD Pi*ZZ individuals from the European AATD Research Collaboration (EARCO) registry and to...

ESR1 mutations are associated with enhanced MTORC1 signaling in a context-dependent manner

Abstract ESR1 mutations are a driver of endocrine therapy resistance in breast cancer, however their impact on protein signaling pathways and clinical outcomes remains poorly understood. We analyzed the transcriptomic, proteomic, and phosphoproteomic landscape of tumors harboring...

Astrocytic activity in treatment-resistant and ultra-treatment-resistant schizophrenia

Astrocytic dysfunction has been implicated in schizophrenia, but biomarkers of astrocytic activity have shown inconsistent patterns. Studies on disease heterogeneity, specifically treatment-resistant schizophrenia (TRS) and ultra-treatment-resistant schizophrenia (UTRS) are lacki...

Low Parental Income During Childhood Is Associated With Coronary Atherosclerosis in Midlife

Background Socioeconomic status (SES) is a major risk factor for coronary heart disease, but the life‐course mechanisms and causal pathways remain poorly understood. Therefore, we investigated whether low childhood SES was associated with midlife coronary atherosclerosis and if a...

4D reconstruction of alumina laser melt pools at 25 kHz via operando X-ray multi-projection imaging

Abstract Advancing additive manufacturing, e.g., laser powder-bed fusion (LPBF), requires resolving rapid processes such as melt-pool dynamics and keyhole evolution in 4D (3D + time). Operando X-ray tomography is a state-of-the-art approach for 4D characterization, but its tempor...