LMU Klinikum

Citation accuracy, citation noise, and citation bias: a foundation of citation analysis

Abstract Citation analysis is widely used in research evaluation to assess the impact of scientific papers. These analyses rest on the assumption that citation decisions by authors are accurate, representing the flow of knowledge from cited to citing papers. However, in practice,...

Intraoperative OCT-Based Stromal Topography in Phototherapeutic Keratectomy

Objectives: This study aims to investigate whether anterior corneal curvature can be reliably measured by combined Placido–optical coherence tomography (OCT) during phototherapeutic keratectomy (PTK) despite intraoperative stromal swelling, and to quantify the immediate smoothing...

GLP-1 Receptor Agonists in Dentistry: Promise, Pitfalls, and Evidence Gaps

GLP-1RAs (glucagon-like peptide-1 receptor agonists) have become one of the fastest-growing drug classes worldwide, with prescriptions for obesity treatment increasing by 587% from 2019 to 2024. While their metabolic and cardiovascular benefits are well established, the implicati...

Disease Duration Differentiates Freezing of Gait Response to Subthalamic and Nigral Stimulation for Parkinson's Disease in an Exploratory Multicenter Controlled Trial

BACKGROUND: Freezing of gait (FoG) belongs to most pressing unmet symptoms in the treatment of Parkinson's disease. OBJECTIVES: To explore whether combined subthalamic and nigral (STN + SNr) deep brain stimulation improves FoG compared with optimized STN stimulation alone; to ide...

Multiple discrimination at work and depressive symptoms in young adults

BACKGROUND: We aimed to estimate the implications of cumulative exposure to discrimination at work for mental health among young adults. Our specific objective was to investigate if experiencing multiple types of discrimination at work is associated with depressive symptoms. METH...

An update on neuro-otology and neuro-ophthalmology – focusing on new developments in the last three years

Vertigo, dizziness, and imbalance are among the most frequent presenting symptoms in primary care and in the emergency department (ED). The clinical diagnosis is based on a structured patient history and bedside examination of the vestibular system and the ocular motor system, lo...

Age-related bone mineral density patterns in a large German clinical DXA cohort: device-specific comparisons with international reference populations

In a large German clinical DXA cohort, comparisons with international reference populations were strongly device-dependent. iDXA values were consistently lower, whereas Prodigy Pro values showed closer but age- and cohort-dependent agreement. The data should not be interpreted as...

Reference values and prediction equations for six-minute walk distance and stair-climbing test performance in apparently healthy Ethiopian adults

The six-minute walk test (6MWT) and stair-climbing test (SCT) are simple and practical measures of functional exercise capacity. Interpretation of performance requires appropriate population-specific reference values and prediction equations. However, reference data for apparentl...

Outcomes of front-line tagraxofusp in patients with blastic plasmacytoid dendritic cell neoplasm (BPDCN) in a real-world scenario

Abstract Tagraxofusp (TAG), a CD123-directed protein-drug conjugate, is approved in front-line and relapsed/refractory blastic plasmacytoid dendritic cell neoplasm (BPDCN). Multicenter real-world outcomes and the contribution of up-front consolidation post-TAG remain less defined...

Impact of on-site mobile CT imaging on prehospital patient management during the Munich Oktoberfest: a retrospective observational before–after study at a mass gathering

Abstract Background Mass gatherings such as the Munich Oktoberfest increase demand on Emergency Medical Services (EMS), particularly for trauma patients requiring imaging. Suspected mild traumatic brain injury (mTBI) often necessitates hospital referral and diagnostic imaging, pl...

Adoption of, attitudes towards, and perceived challenges of digital health in hospice and palliative care among professionals in Germany: a national cross-sectional web-based survey

Abstract Background Digital health technologies may support communication, symptom management, continuity of care, and access to services in hospice and palliative care. National data on their adoption, on professionals’ attitudes, and on perceived barriers are scarce. We examine...

Place and cause of death among people with chronic neurological diseases in Munich: a population-based study using death certificates

Abstract Introduction Access to palliative care is often delayed and fragmented for patients with chronic neurological diseases. This study aimed to characterize the place and cause of death among individuals with chronic neurological diseases to help identify potential gaps in p...

Enumeration of Regular Multipartite Hypergraphs

Abstract. We determine the asymptotic number of regular multipartite hypergraphs, also known as multidimensional binary contingency tables, for all values of the parameters.

Understanding Genomic Instability Score in Platinum-Treated Advanced Pancreatic Ductal Adenocarcinoma

Background/Objectives: First-line treatment selection for advanced (locally advanced or metastatic) pancreatic ductal adenocarcinoma (PDAC) is currently based on clinical characteristics rather than predictive biomarkers. While homologous recombination deficiency (HRD) is associa...

Migratory dermal γδ T cells determine the balance between lung immunity and tissue damage during helminth infection

Many helminth parasites migrate through multiple host organs during infection, but how immune responses are relayed across these tissues is still poorly understood. To investigate the immune aspects of intertissue communication during infection, we established a percutaneous infe...

Can We Diagnose Early Melanoma With New Imaging Technologies?

Multimodal imaging enables risk-adapted early melanoma diagnosis by integrating dermoscopy, OCT, in vivo RCM, ex vivo RCM, and LC-OCT. These technologies provide complementary architectural, cellular, and perioperative information, supporting improved diagnostic precision while r...

Incidence and Predictors of Complications After Transcatheter Aortic Valve Implantation According to VARC‐3 Criteria: A Systematic Review and Meta‐Analysis

BACKGROUND: Despite continuous advancements in devices and techniques, transcatheter aortic valve implantation remains associated with complications impacting outcomes. In 2021, the Valve Academic Research Consortium (VARC) introduced the VARC-3 criteria to better classify proced...

Diagnosing autoimmune encephalitis in psychiatry: clinical recommendations and unresolved challenges from the GENERATE network

Psychiatric syndromes can be caused by underlying autoimmune encephalitis (AE). This represents a diagnostic challenge at the interface of psychiatry and neurology. While AE mostly manifests with a combined, complex neuropsychiatric syndrome, some patients with AE may (initially)...

Limit laws for critical dispersion on complete graphs

We consider a synchronous process of particles moving on the vertices of a graph G, introduced by Cooper, McDowell, Radzik, Rivera and Shiraga (Random Structures Algorithms 53 (2018) 561–585). Initially, M particles are placed on a vertex of G. In subsequent time steps, all parti...

Insurance as commitment?

Abstract Most insurance decisions combine risk management and an intertemporal dimension. Yet while non‐canonical behavioral models have been applied extensively to the risk management aspect, they are mostly missing from the intertemporal component. We expand insurance demand th...