Kobe University

Gendered cultural discourse in Japan across the prewar–postwar transition: evidence from historical word embeddings

Abstract We quantify the evolution of gender stereotypes in Japan from 1900 to 1998, covering the prewar–postwar transition, using a series of yearly word embeddings trained on historical text corpora. We define the gender stereotype value to measure the strength of a word’s gend...

Response to the Letter Regarding “Methodological Considerations in Real‐World Evaluation of Durvalumab Plus Tremelimumab for Unresectable Hepatocellular Carcinoma”

Data supporting the findings of this study are available from the corresponding author upon reasonable request, subject to institutional review board approval and execution of appropriate data sharing agreements.

Association Between PS-OCT Derived Polarimetric Entropy and RPE Cellular Metrics Measured With Adaptive Optics Imaging in Retinitis Pigmentosa

Purpose: The purpose of this study was to investigate the association between entropy values derived from the retinal pigment epithelium (RPE) layer using polarization-sensitive optical coherence tomography (PS-OCT) and RPE cellular metrics obtained by adaptive optics transsclera...

Associations between jump-derived mechanical indicators and sprint performance across sprint sections in baseball players

The purpose of this study was to examine the relationships between sprint performance across discrete distance sections and mechanical indicators derived from ballistic and reactive jumping tasks in male collegiate baseball players. Sixty-two players performed maximal 40-m sprint...

Clinical and molecular characteristics of thalamic gliomas in adults: prognostic impact of TERT promoter mutation

BACKGROUND: Adult thalamic gliomas (ATGs) are rare and biologically heterogeneous tumors. Although the 2021 World Health Organization (WHO) classification designates all diffuse midline gliomas (DMGs), H3-altered, as grade 4, accumulating evidence suggests that adult thalamic DMG...

A multidimensional analysis of CGM-derived glucose metrics in type 1 diabetes: differential associations of insulin degludec and insulin glargine U300

Ultra-long-acting basal insulins, insulin degludec (IDeg) and insulin glargine U300 (IGlarU300), are widely used in type 1 diabetes mellitus (T1DM), but their differential effects on multidimensional continuous glucose monitoring (CGM) profiles remain unclear. We aimed to identif...

Modeling user redemption behavior in complex digital incentive environment: an empirical study using large-scale transactional data

Abstract The digital economy implements complex incentive systems to retain users through point redemption. Understanding user behavior in such complex incentive structures presents a fundamental challenge, especially in estimating the value of these digital assets against tradit...

Genetic characterizations and seroprevalence of hepatitis B virus among non-human primates and human caretakers in Indonesia

Hepatitis B virus (HBV) is a major human pathogen also detected in non-human primates (NHPs), yet its cross-species and zoonotic transmission potential remains poorly defined. We screened 237 NHPs across 10 species together with 65 human caretakers from four major Indonesian isla...

Exploring vertical genomic heterogeneity and chemotherapy response using targeted genomic sequencing in muscle-invasive bladder cancer

We performed a targeted genomic sequence of muscle-invasive bladder cancer (MIBC) tissues to investigate vertical intratumoral heterogeneity, invasion processes, and potential biomarkers of platinum-based neoadjuvant chemotherapy (NAC) efficacy in MIBC. Mutations in key genes tho...

Engineering a Highly meta -Selective Biphenyl Monooxygenase for the Biosynthesis of High-Value Polymer Precursors

Abstract The meta-selective C–H functionalization of aromatic substrates lacking meta-directing electron-withdrawing groups remains challenging. To engineer the regioselective enzymatic conversion of biphenyl (BP) to 3,3′-dihydroxybiphenyl (33DHBP), an industrial precursor to hig...