Izmir University

Experimental research: biomechanical evaluation of iliosacral screw fixation effects on sacral and iliac screw strain in lumbosacral and lumbopelvic constructs

Background: The biomechanical impact of iliosacral screw fixation (ISF) on lumbosacral fixation (LSF) and lumbopelvic fixation (LPF) constructs remains unclear. This study evaluates the effects of ISF on screw strain distribution and construct stability in these fixation models....

Contribution of One‐Electron Oxidation of Purine and Pyrimidine Bases to the Photo‐ and Radiation‐Induced Damage to Cellular DNA

One‐electron oxidants that include type I photosensitizers, biologically relevant carbonate anion radical generators, and high intensity UVC nanosecond lasers are able to ionize in aqueous solution purine and pyrimidine nucleobases. The survey is aimed at critically reviewing the...

Blood Pressure and Angina-Related Health Status During Benidipine Therapy: A Multicenter Real-World Cohort Study

Background: Benidipine is a long-acting calcium channel blocker used for the treatment of hypertension and chronic coronary syndrome. Although it effectively lowers blood pressure (BP), the relationship between BP reduction and improvement in angina-related health status during b...

From anatomy to surgical safety: scenario-based learning for internal carotid artery patterns in undergraduate education

Abstract Background This study aimed to evaluate the educational value of scenario-based anatomy training using patient-specific three-dimensional models of internal carotid artery (ICA) anatomical patterns. Methods A total of 120 first-year medical students were assigned to eith...

Impact of adjuvant endocrine therapy on disease-free survival in early triple-positive breast cancer: a multicenter retrospective cohort study of the Turkish oncology group

Triple-positive breast cancer (TPBC), characterized by concurrent ER, PR, and HER2 positivity, poses unique therapeutic challenges due to ER–HER2 crosstalk. The optimal adjuvant endocrine therapy in TPBC patients receiving anti-HER2 regimens remains poorly defined. This multicent...