Iran University of Medical Sciences

Perspective-taking in ICU nurses: a qualitative descriptive study

Abstract Background Perspective-taking is the cognitive and emotional process of understanding patients’ experiences from their viewpoint and is central to empathic, patient-centered care in intensive care units (ICUs). However, the ways ICU nurses draw on personal and profession...

The predictive value of ultrasonographic gallbladder wall thickness for complications in laparoscopic cholecystectomy

Gallbladder wall thickening on preoperative ultrasonography may reflect inflammation and fibrosis and may be associated with more difficult laparoscopic cholecystectomy. This study evaluated the association between ultrasonographic gallbladder wall thickness and operative duratio...

Family-related Factors Associated With Readmission Among Children and Adolescents With Psychiatric Disorders

Background: Psychiatric readmission among children and adolescents is a major concern in mental health services and is influenced by clinical, familial, and demographic factors. However, the contribution of family-related variables remains insufficiently understood, particularly...

Challenges of parliamentary engagement in health policymaking in Iran: a qualitative study using Gaventa’s power cube framework

Parliaments play an important role in health governance through legislation, budgeting and oversight. However, their practical influence on health policy decisions remains poorly understood in systems where executive institutions and expert actors dominate policy processes. In Ir...

Crafting the DNA of smart hospitals: decoding standards and indicators through a scoping review

The significant global spread of smart hospitals emphasizes the need for clear and well-defined criteria and standards to effectively guide their design, implementation, evaluation, and management. This scoping review aimed to clarify the requirements for smart hospitals by exami...

Anticancer Drugs and Cancer-Associated Thrombosis

The rapid development of novel cancer therapies has considerably improved the care of cancer patients and cancer-related survival; however, these therapies are associated with a broad range of adverse events that have become a major burden in this population. Alongside other canc...

Storytelling for fostering a culture of safety in healthcare: a quasi-experimental study

Patient safety is a critical component of healthcare, emphasizing the prevention of errors and adverse events that may harm patients during medical care delivery. This study aimed to investigate the impact of storytelling training on patient safety culture amongst nurses at Firuz...

Evaluation of changes in quality of life, life satisfaction, and anxiety following in-person and virtual dignity therapy in patients with heart failure: a quasi-experimental controlled study

Dignity therapy is a life review intervention that can help reduce existential and spiritual distress in patients with heart failure. However, there is limited evidence comparing the two delivery modes (in-person and virtual) of this intervention. This study aimed to evaluate cha...

Fronto-temporal transcranial direct current stimulation reduces symptoms in treatment-resistant schizophrenia: a randomized sham-controlled trial

Treatment-resistant schizophrenia (TRS) remains a major clinical challenge, with limited response to pharmacotherapy. Transcranial direct current stimulation (tDCS) has emerged as a potential adjunctive treatment, although evidence regarding its efficacy remains inconsistent. To...

Familial nemaline myopathy and multiple sclerosis: a case report exploring a novel co-occurrence with familial clustering

Nemaline myopathy (NM) and multiple sclerosis (MS) are distinct disorders with different genetic or epigenetic characteristics, and their co-occurrence has not been priorly documented. We report a 40-year-old male with a notable familial history of both NM and MS who was diagnose...

Combination of Empagliflozin and Resveratrol Mitigates Hepatic Steatosis via Attenuation of Inflammation and Promotion of Adipose Tissue Browning in High‐Fat Diet‐Fed C57BL / 6J Mice

ABSTRACT Metabolic dysfunction‐associated steatotic liver disease (MASLD) is a major hepatic complication of obesity with a complex pathogenesis. This study aims to investigate the combined effects of empagliflozin (EMPA) and resveratrol (RSV) treatment on obesity‐associated MASL...

Possible role of bacterial infection in embryo implantation failure

Embryo implantation is a critical and complex process that requires coordination between the embryo and the receptive endometrium for its success. However, a multitude of factors have the potential to contribute to implantation failure. Among these factors, bacterial infections i...

Diagnostic accuracy of droplet digital PCR for BRAF mutation detection in thyroid specimens: a systematic review and meta-analysis

BRAF mutation testing, particularly for BRAF V600E, may provide adjunctive diagnostic information in the evaluation of thyroid nodules when interpreted alongside cytology, ultrasonography, and clinical risk. Droplet digital polymerase chain reaction (ddPCR) enables sensitive dete...

The Role of Ultra‐Low‐Dose Naloxone as an Additive in Anesthesia and Nerve Block: A Systematic Review

ABSTRACT Background and Aims In anesthesia and analgesia, opioids alone or in combination with local anesthetics (bupivacaine, lidocaine, and ropivacaine) have been investigated to prolong peripheral nerve blocks. Ultra‐low‐dose naloxone administration in local anesthetic solutio...

Barriers and facilitators of vector-borne diseases knowledge translation: a scoping review

Vector-borne diseases (VBDs) such as leishmaniasis, dengue, and malaria continue to pose major public health challenges, driven by environmental, socioeconomic, and climatic factors. Although numerous studies have generated valuable evidence, research findings are rarely translat...

Short‐Term Clinical Comparison of Scapular Stabilization With and Without Added Kinetic‐Chain Exercises on Pain, Scapular Kinematics, and Upper‐Extremity Function in Overhead Athletes With Subacromial Pain Syndrome: A Randomized Controlled Trial

BACKGROUND AND PURPOSE: Scapular stabilization exercises are commonly used in the rehabilitation of athletes with subacromial pain syndrome (SAPS) and scapular dyskinesis. Whether supplementing scapular stabilization with kinetic-chain exercises provides greater short-term benefi...

Incident cardiovascular disease across the spectrum of estimated glomerular filtration rate (eGFR) in a population of Iranian people with type two diabetes mellitus

The association of estimated glomerular filtration rate (eGFR) with cardiovascular disease (CVD) and all-cause mortality among people with type two diabetes (T2DM) is less described. We aimed to investigate these associations in a population of Iranian people with T2DM. This retr...

Coated or chewable Aspirin and a hybrid air pollution mitigation strategy in patients with atherosclerotic disease: Rationale and Design of the COATED-AIR Randomized Trial.

BACKGROUND: Although enteric-coated aspirin is widely used instead of chewable formulations in patients with atherosclerotic cardiovascular diseases (ASCVD), its effects on cardiovascular and gastrointestinal outcomes remain uncertain. Separately, air pollution is a driver of car...

Bifidobacterium longum prevent the progression of colon cancer via inhibiting metastasis and angiogenesis

Colorectal cancer (CRC) is one of the most common reasons for cancer-related death, and both angiogenesis and metastasis have established roles in CRC progression. Recent findings suggest that probiotics, like Bifidobacterium longum, are capable of suppressing anti-cancer activit...

Contemporary global prevalence and genotype distribution of human papillomavirus among female sex workers, 2015–2025: an updated systematic review and meta-analysis

Abstract Background Female sex workers experience disproportionate exposure to human papillomavirus (HPV), but estimates of HPV prevalence and genotype distribution vary according to geography, specimen type, diagnostic method, and genotype coverage. This updated systematic revie...