Institució Catalana de Recerca i Estudis Avançats

Spurious Drifts in the ITCZ Location and Associated Atmospheric Circulation in Decadal Climate Predictions

Abstract Decadal predictions are affected by initialization shocks and drift, typically diagnosed in ocean circulation or temperature. It is not known, however, to what extent the drift can affect atmospheric dynamics. Here we investigate how the drift causes spatial shifts in th...

Dynamic Functional Synchronization Profiles in Autism Differ by Spatial Scale and Along Hierarchical Cortical Gradients.

Background: Prevailing theories propose that autism is characterized by local cortical overconnectivity and long-range underconnectivity, but empirical evidence remains mixed. Methods: = 1009) to examine how functional synchronization profiles dynamically change over time and acr...

Cognitive vergence and pupillary responses as functional oculomotor signatures to differentiate AT(N) biological profiles in older adults with mild cognitive impairment

Abstract The locus coeruleus (LC), the earliest site of tau accumulation in Alzheimer’s disease, directly influences pupillary and vergence oculomotor systems. Whether task-evoked oculomotor dynamics can non-invasively differentiate AT(N) profiles, A+T+ (biological Alzheimer’s di...

Healthcare cultures and the implementation of WHA77.2: from measurement to institutional change

Resolution WHA77.2 establishes an unprecedented mandate for meaningful social participation in health decision-making. The resolution, and the operational guidance that preceded it, already address representation, power, deliberation, feedback, policy influence, and evaluation. I...

MOF‐Derived Cu‐TiO 2 /Alginate Micromotors for Buoyancy‐Regulated 3D Motion

ABSTRACT Micro‐ and nanomotors (MNMs) promise impact in the areas of environmental remediation and biomedicine, but reliable three‐dimensional (3D) control remains challenging. Conventional bubble‐propelled MNMs can move in 3D, yet their trajectories are stochastic and energy‐ine...

Deep molecular profiling of lung neuroendocrine tumours and supra-carcinoids

BACKGROUND: Lung neuroendocrine tumours (NETs, also known as carcinoids) are rapidly rising in incidence worldwide but have unknown aetiology and limited therapeutic options beyond surgery. The current WHO classification, based on mitotic count and presence or absence of necrosis...

ODIN: Confirmation and 3D Reconstruction of Six Massive Protoclusters at Cosmic Noon

Abstract Protoclusters represent sites of accelerated galaxy formation and extreme astrophysical activity characteristic of dense environments. Identifying massive protoclusters and mapping their spatial structures are therefore crucial for understanding how large-scale environme...

Ultraslow brain dynamics as neurophysiological markers of information sampling during learning

To learn, we must actively sample information from our environment: selecting, prioritizing, and extracting relevant cues. Here, we investigated whether ultraslow event-related potentials (ERPs) could track information sampling as participants learned new words from sentence cont...

Layered Nickel–HHTP Networks for Efficient Chemiresistive Sensing of CH 4 and CO 2

ABSTRACT The synthesis and single‐crystal structural elucidation of Ni‐HHTP are reported for the first time, achieved from crystals of sufficient size for electron diffraction analysis. These studies reveal that the crystal structure of Ni‐HHTP alternates between radical‐rich and...

Valenced Encounters: Exploring the Affective Component of Implicit Attitudes

Abstract Implicit attitudes typically involve a valence—an affective component that reflects a positive or, more often, negative appraisal of members of socially relevant categories. Surprisingly, however, discussions of implicit attitudes have paid little explicit attention to v...

Emergent Bell phase in an electro-nanomechanical quantum simulator

Suspended carbon nanotubes hosting electrostatically defined quantum dots allow for exceptionally strong and tunable electromechanical coupling as well as mechanical modes that can reach the quantum ground state of motion simply by cryogenic cooling. This makes them a unique plat...

Decoding the hearth: micromorphology and experiment in iron age domestic fire structures (NE Iberian Peninsula)

Combustion structures documented in protohistoric settlements are considered to be defining elements of domestic spaces, and are usually associated with a culinary function. In the case of the Mediterranean coast of the Iberian Peninsula during the Iron Age, the hearth is often u...

Magnetoelectric BaTiO 3 /CoFe 2 O 4 Thin‐Film Meshes for Neuronal Differentiation

ABSTRACT Magnetoelectric composites offer a powerful route for remotely converting magnetic stimuli into local electrical cues, with promising biomedical applications in electrical stimulation. In strain‐mediated magnetoelectric heterostructures, however, efficient coupling depen...

The sweet spot in protein design—Where deep learning meets first principles

This Perspective explores recent methods and prospective ideas for developing hybrid AI-physics-based pipelines for protein and antibody de novo design. We argue that the highest-confidence candidates emerge where deep learning and first-principles models agree, a "sweet spot" th...

Converging pathomechanisms link SARS-CoV-2 infection with major neurodegenerative diseases

Neurological complications are among typical clinical manifestations, both during the acute phase of SARS-CoV-2 infection and long-term post-acute COVID-19 sequelae, i.e., Long COVID. A growing body of evidence connects SARS-CoV-2 infection to systemic inflammation, peripheral im...

Global trade-offs between consumption, carbon prices and equity

As the remaining carbon budget continues to dwindle, economic growth strains efforts to limit global warming to 1.5 °C. Reducing unnecessary production and consumption in high-income regions and among the wealthy, and organising production more around human needs and human well-b...

Review of Particle Physics *

The Review summarizes much of particle physics and cosmology. Using data from previous editions, plus 3,200 new measurements from 903 papers, we list, evaluate, and average measured properties of gauge bosons and the recently discovered Higgs boson, leptons, quarks, mesons, and b...

Observational signatures of negative mass wormholes through their shadows

Abstract Systems containing objects with negative mass (NMOs) are considered. Such a system consists of one object with positive mass and one NMO, where a bound state exists even though the force exerted by the NMO on the object with positive-mass is repulsive. Unlike standard bi...

Neuropeptide Y—Graphene Oxide Complexes Inhibit Amygdala NPY‐Receptor Expressing Glutamatergic Pathways and Selectively Remove Aversive Memory In Vivo

Therapeutic needs to modulate brain circuits highlight graphene-based materials (GBMs) as an emerging tool to engineer specific interventions to treat neuro-diseases. In this context, graphene oxide (GO) nanosheets offer new drug delivery strategies to reach neural cells and sign...