Guizhou University

Effect of Baijiu bottom pot water on the chemical composition, microbial community and in vitro ruminal fermentation of king grass silage

Bottom pot water (BPW), a distillation by-product from the Baijiu industry, is rich in organic compounds but poses a disposal challenge. This study investigated the effects of BPW and Lentilactobacillus buchneri , on fermentation quality, chemical profiles, and bacterial communit...

Transcriptome Reversal in Sulfate Transporter Involves Abiotic Stress in Sesuvium portulacastrum L.

Sulfur is an essential nutrient involved in plant growth, redox regulation, and responses to environmental stresses. Sulfate transporters (SULTRs) control sulfate uptake and distribution, thereby affecting sulfur availability for metabolic processes and stress adaptation. However...

Transcriptome profiling analysis of heat-adapted and heat-sensitive breeder hen jejunal mucosal tissues in response to acute heat stress

<title>Abstract</title> Background Heat stress impairs intestinal integrity in poultry, compromising nutrient digestion and absorption. Nevertheless, the individual variation in heat tolerance suggests distinct molecular responses that are still not well understood. Materials and...

Divergent Synthesis of Functionalized Spiroindanediones via CdI2/MgI2-Catalyzed Multiple Cyclocondensation Modes

Abstract Divergent synthesis enables rapid construction of structurally diverse compound libraries from the same universal substrates and is a current research hotspot. Here, the self-(3 + 2), (2 + 1), and (1 + 1 + 1) cyclocondensations of 2-arylidene-1,3-indanediones 1 were real...

Phased fuel transitions for decarbonizing the Asia–Europe Green Shipping Corridor

Shipping remains almost entirely reliant on fossil fuels, and identifying viable fuel transition pathways under evolving regulations is a key challenge. A study now evaluates 13 alternative marine fuels for the Asia–Europe corridor, revealing phased transitions shaped by policy d...

A knowledge tracing model based on heterogeneous exercise graphs and multi-source behavioral feature fusion in blended learning environments

With the widespread adoption of blended learning, learner data have evolved from single response sequences to multi-source heterogeneous behaviors spanning pre-class preparation and in-class interaction. This poses new challenges for traditional knowledge tracing methods in model...

Two Earliest Optical-UV Tidal Disruption Events Hidden in the SDSS DR7 Catalog Unveiled by the Transformer-based Spectrum Classifier

Abstract Optical spectroscopic features are decisive in the current identification of optical-UV tidal disruption events (TDEs). Regarding that the TDE estimated occurrence rate is 10 −5 –10 −4 galaxy −1 yr −1 by both theoretical and observational methods, large optical spectrosc...

Novel N -PhenylphthalimideDerivatives as Protoporphyrinogen IX Oxidase-Targeted Inhibitor Herbicides

Abstract The use of herbicides represents one of the effective weed management strategies. To create high-efficiency, low-risk protoporphyrinogen IX oxidase (PPO)-targeted herbicides, a set of novel N-phenylphthalimides bearing 1,3,4-oxadiazole and acylhydrazide fragments was des...

NIR-activated NO-propelled nanomotors for deep tumor penetration and DNA-repair sensitized photothermal therapy of prostate cancer

Photothermal therapy (PTT) for solid prostate cancer (PCa) is often limited by poor intratumoral penetration and rapid DNA repair. Herein, we engineered a PSMA-targeted gas nanomotor that couple deep tumor penetration with DNA repair sensitization for enhanced photothermal/NO the...

Multimodal BERT exploration of uncertain project resilience evolution via textual and log data joint modeling

To address the need for dynamic project resilience evaluation under uncertainty and the difficulty of jointly modeling risk texts and execution logs, this study proposes a Multimodal-BERT joint modeling framework for analyzing project resilience evolution. The framework combines...

Design, synthesis, and biological activity studies of formononetin derivatives containing pyrazole amide moieties

Abstract BACKGROUND Global food security faces dual challenges from pathogen threats and increasing fungicide resistance, urgently necessitating the development of new pesticides that are efficient, low‐toxicity, and environmentally friendly. Natural products, owing to their stru...

Substrate-AssistedRedox-Neutral Formal [4 + 3] Annulationof Alkynyl Aldehydes with 9,10-Phenanthrenequinones via N-HeterocyclicCarbene Catalysis

Abstract Medium-sized oxygen-containing heterocycles are important structural motifs in natural products and functional molecules, yet their efficient synthesis remains challenging. Herein, we disclose a N-heterocyclic carbene (NHC)-catalyzed redox-neutral formal [4 + 3] annulati...

Effects of monensin residues on microbial community and the attenuation of antibiotic resistance genes during chicken manure composting

Monensin is a polyether ionophore antibiotic widely used to prevent coccidiosis and inhibit Gram-positive bacteria. Composting is widely regarded as an effective strategy for reducing the abundance of antibiotic resistance genes (ARGs) in manure. However, the long half-life of mo...

Objective–Subjective Socioeconomic Status Configurations, Self-Acceptance, and Adolescent Prosocial Moral Reasoning: A Response Surface Analysis

Background: Objective and subjective socioeconomic status capture distinct aspects of adolescents’ socioeconomic experience, but their joint associations with prosocial moral reasoning and self-acceptance remain unclear. This study examined objective–subjective socioeconomic stat...

Damage evolution of coal under SHPB impact and multi-scale simulation

As energy exploitation advances, operations are increasingly moving into deep coal seam regions. Understanding the dynamic mechanical properties of coal seams under complex stress conditions in such deep-seated environments has become a key focus in mining engineering. In this st...

One-Pot Rapid Synthesisof Kinked Gold Nanowires withHigh SERS Activity

Abstract Developing a simple method to prepare a nanostructure with high SERS activity is crucial for achieving efficient and rapid trace detection and even single-molecule detection. However, conventional methods often struggle to reconcile these two requirements simultaneously....

Capturing microclimates: 30-m downscaled climate dataset reveals fine-scale suitability patterns of invasive pests in karst landscapes

Karst landscapes are characterized by extreme topographic heterogeneity, which limits the capacity of conventional coarse-resolution climate data to resolve local microclimates, thereby introducing uncertainty into biological invasion risk assessments. This study developed a high...

Strain Effectson the Mechanical Properties and GasAdsorption and Diffusion Characteristics of Anthracite

Abstract The coal matrix is subjected to complex strain conditions during exploration. Pore structural evolution, gas adsorption, and diffusion characteristics of high-rank coal matrix under uniaxial compressive and tensile strain conditions are investigated through molecular sim...

Constructing co-assembly derived smart lipid nanoparticles for enhanced antimicrobial potency with plant growth-promoting potential

Lipid nanoparticles (LNP) are widely used in biomedical applications due to their biocompatibility and safety, yet their translation to plant systems remains limited. Here, we establish a unified strategy integrating antibacterial compound discovery, plant-adapted nanocarrier des...

Hydrodynamic phase entrainment drives synchronization of sperm flagella

Synchronization of sperm flagella may enhance reproductive fitness and offers an accessible model for studying biological coordination. However, a fundamental debate persists: while hydrodynamic models predict that fluid coupling alone can synchronize adjacent flagella, experimen...