ETH Zurich

Deep generative model for human mobility behavior

Understanding and modeling human mobility is central to challenges in transport planning, sustainable urban design, and public health. Despite decades of effort, simulating individual mobility remains challenging because of its complex, context-dependent, and exploratory nature....

Directed Evolution of an Escherichia coli Secretor Strain Using the Curli Pathway

Abstract A key goal of many bacterial engineering projects is to produce protein, due to their potent chemical and material functions. However, recombinant proteins are usually produced intracellularly, and secreting arbitrary proteins directly into an extracellular environment i...

Distribution of device-measured 24-hour movement behaviours across the cognitive spectrum in older adults: the HUNT study

Abstract Background Key daily physical activities (e.g., standing and walking), postures (sitting and lying), and sleep constitute the 24-h day and have distinct health effects and functional implications. Traditionally studied separately, the distribution of these movement behav...

Middle atmosphere chemical and dynamical effects in the CCMI-2022 stratospheric aerosol injection scenario

Abstract. Stratospheric aerosol injection (SAI) could slow surface warming, however, potential side effects include changes in stratospheric ozone and changes in regional surface temperatures and precipitation resulting from tropical lower stratospheric warming. Previous multi-mo...

A new framework for non-stationary spatio-temporal data fusion of multi-fidelity models

We propose a new scalable framework for spatio-temporal data fusion with multi-fidelity Gaussian processes (MFGPs) that enables fully likelihood-based inference for both stationary and non-stationary fidelity integration. The framework is designed for environmental applications,...

The upper B 2 <mml:math xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:mnf="http://cambridge.org/core/manifest" xmlns:cup="http://contentservices.cambridge.org" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:m="http://cambridge.org/core/metadata" xmlns:core="http://cambridge.org/core" xmlns:c="http://cambridge.org/core/content"> <mml:msub> <mml:mi>B</mml:mi> <mml:mn>2</mml:mn> </mml:msub> </mml:math> $B_2$ index of galled trees

Abstract In recent years, there has been effort to extend the classical notion of phylogenetic balance, originally defined in the context of trees, to networks. One of the most natural ways to do this is with the so-called upper B 2 <mml:math xmlns:xlink="http://www.w3.org/1999/x...

FreeLayout: Free range multi-modal input to free form floorplan generation

Automated floorplan generation has advanced rapidly, yet most methods remain constrained to orthogonal geometry, single-scale synthesis, and fully specified inputs—mismatched to real practice where designers iterate from sparse, evolving cues and irregular floor footprints. We pr...

Redistributed, Not Reduced: The Role of International Trade in Global Food Supply Sustainability

Global food systems must balance productivity with environmental sustainability amid climate change, geopolitical shocks, and unevenly distributed natural resources. This study introduces the Food Supply Sustainability Index (FSSI), a transparent, composite measure of the sustain...

Degradable Alternating Copolymers With Strained Cyclobutane Backbones via Photocontrolled RAFT Polymerization

ABSTRACT In this study, we report a reversible addition‐fragmentation chain transfer (RAFT) alternating copolymerization of 1,3‐disubstituted bicyclo[1.1.0]butanes (BCBs) with maleimides, maleic anhydride, or bio‐based fumarate derivatives, affording a class of well‐defined copol...

Support effects and design rules for enhanced phosphotungstic acid catalyzed olefin oligomerization to sustainable aviation fuels

Reducing the environmental footprint of aviation fuels requires catalysts that convert renewable olefins to jet-fuel hydrocarbons (JF). In this context, supported phosphotungstic acid (PTA) emerged as a promising Brønsted acid catalyst for this transformation. The performance of...

Glacier retreat shapes organic nutrient availability across lake succession

Glacier retreat is rapidly transforming landscapes, creating thousands of new lakes that act as natural laboratories of ecological succession. In these newly formed ecosystems, colonizing animals must meet their requirements for essential organic nutrients, such as long-chain pol...

Ly6d expression delineates two putative postnatal thymus epithelial progenitor cells that are differentially affected by aging

To date, the identity and maintenance of postnatal thymic epithelial progenitor cells (TEPCs) remain unclear, as does the persistence of bipotent TEPCs after birth or whether lineage-restricted progenitors independently maintain separate TEC compartments. Using an inducible linea...

Policy (dis)integration in water management: a historical analysis of a Swiss case

Abstract Over the past 170 years, water management in Switzerland has undergone a profound transformation. What began as a localized, event-driven practice shaped by immediate needs and local initiative—such as efforts to ensure flood protection—gradually evolved into a complex,...

Synergies and trade-offs for reaching global biodiversity and climate commitments

The Kunming-Montreal Global Biodiversity Framework strives to expand high-quality protected areas globally, yet faces economic constraints, climate change and human pressures. This requires integrating biological and socio-economic complexity while ensuring equity. We explore mul...

Review of Particle Physics *

The Review summarizes much of particle physics and cosmology. Using data from previous editions, plus 3,200 new measurements from 903 papers, we list, evaluate, and average measured properties of gauge bosons and the recently discovered Higgs boson, leptons, quarks, mesons, and b...

Accelerated carbonation of recycled concrete aggregates: Binding of CO2 and decalcification of calcium-silicate-hydrate

Recycled concrete aggregates (RCA) are a valuable resource for reuse as aggregates in concrete and asphalt. However, the porous mortar adhering to the original aggregates and microcracks both in the mortar and at the interfaces result in increased water absorption and reduced mec...

Reduced Complexity Model Intercomparison Project phase 3: experimental protocol for coordinated constraining and evaluation of reduced-complexity models

Abstract. Reduced-Complexity Models (RCMs) are a critical tool for synthesising climate science knowledge and providing climate projections for a wide range of emissions scenarios. The Reduced-Complexity Model Intercomparison Project (RCMIP) provides a framework for the coordinat...

Perceived Livelihood Vulnerabilities of Artisanal Fishers in Elmina, Ghana, in Relation to Chinese‐Controlled Industrial Trawling

ABSTRACT This study examines the perceived livelihood vulnerabilities reported by artisanal fishers in Elmina, Ghana, in relation to Chinese‐controlled industrial trawling. Using a mixed‐methods design, it combined eight in‐depth interviews, 12 mini‐group discussions, informal co...

Toward continuous shrinkage measurement of poured earth: practical setup and underlying shrinking mechanisms

Abstract Continuous shrinkage measurement in earth-based materials remains technically challenging, particularly for high-water-content mixtures with low initial stiffness. In this study, a semi-cylindrical experimental setup, combined with digital image correlation (DIC) for mea...

Not just alignment: body shape influences adult spinal deformity biomechanics

Abstract Purpose Adult spinal deformity (ASD) alters sagittal alignment and trunk centre of mass location, increasing spinal loading. Current clinical assessment of ASD primarily focuses on alignment parameters disregarding patient’s body shape variability. This study aimed to ev...