Chungnam National University

Uncertainty quantification and parameter optimization of a plasma etching process using a heteroscedastic Gaussian process

This study presents an uncertainty-aware framework for the reliability-based robust design optimization (RBRDO) of plasma etching processes in semiconductor manufacturing. The framework is demonstrated using experimental measurements of the remaining thickness collected at nine w...

Discovery and initial validation of biomarkers for early detection and monitoring of laryngeal cancer using a blood-based microRNA

Laryngeal cancer (LC) is a common head and neck malignancy for which early detection and disease monitoring remain clinically important. We sought to identify and validate microRNAs (miRNAs) as potential non-invasive biomarkers for LC. Candidate miRNAs were screened through diffe...

Synchrotron X-ray-informed machine learning for local hardness mapping in a Cu–Ni–Ti–Hf–Zr high-entropy shape-memory alloy

A supervised machine-learning framework was used to relate colocated synchrotron X-ray fluorescence (XRF), X-ray nanodiffraction (XND), thermodynamic descriptors, and nanoindentation measurements to local hardness in an as-cast Cu 15 Ni 35 Ti 25 Hf 12. 5Zr 12.5 high-entropy shape...

Improving OER performance in alkaline water electrolysis with a Zn-doped NiFe LDH electrode developed via self-growth precipitation

Developing cost-effective, scalable non-noble-metal electrocatalysts for the oxygen evolution reaction (OER) is essential for alkaline water electrolysis (AWE). Zn-doped NiFe layered double hydroxide (LDH) was synthesized via self-growth precipitation. Zn-incorporated NiFe LDH ex...

Co-evolutionary pathways of synthetic biology regulation: A comparative analysis of major countries and Korea's strategic legislation

The convergence of synthetic biology and artificial intelligence is widening the gap between technological advancement and existing regulatory frameworks - a phenomenon known as regulatory lag. As global competition intensifies to capture a synthetic biology market projected to r...

Sodium‐Induced Process Window Expansion Enables High‐Performance Solution‐Processed CISSe Thin‐Film Solar Cells for Tandem Applications

ABSTRACT This work reports a sodium‐enabled breakthrough in air‐processable N,N‐dimethylformamide (DMF) molecular ink routes for CuIn(S,Se) 2 (CISSe) solar cells. Excess Na incorporation significantly expands the otherwise narrow air annealing temperature (AAT) window required fo...

Influence of plant metabolic disruptors on glufosinate weed control

Additives that disrupt plant metabolic pathways might be an option to obtain higher stability in weed control levels when applying herbicides impacted by environmental conditions. Field experiments were conducted to determine if the addition of metabolic inhibitors, such as NBD-C...

Design principles for stable and balanced multigene expression in plant synthetic biology

Abstract Plant synthetic biology is increasingly moving from single-gene transformation toward multigene systems that reconstruct metabolic pathways, produce valuable proteins, implement synthetic circuits, and respond to environmental inputs. However, stable multigene expression...

A review of Panelus occurring in the Korean Peninsula (Coleoptera, Scarabaeidae, Scarabaeinae) with descriptions of two new species

A taxonomic review of Korean Panelus Lewis is presented based on morphological and molecular characters ( COI ). Detailed comparison of morphological characters and molecular analyses using genetic divergence and gene-tree monophyly for species delimitation support the descriptio...

Effects of neutral detergent fiber content and its source on growth performance, rumen characteristics, digestibility, and methane concentrations in Hanwoo heifers

Objective: This study investigated the effects of neutral detergent fiber (NDF) content and NDF source (forage-or concentrate-derived) on growth performance, rumen characteristics, nutrient digestibility, and methane (CH4) concentrations in growing Hanwoo heifers.Methods: Thirty...

Polypropylene Microplastics Disrupt Epithelial Barrier Integrity and Viability in Human Airway Epithelial Cells

Objective To investigate the effects of polypropylene microplastics (PP-MPs) on the integrity and viability of upper airway epithelial cells and to elucidate the underlying mechanisms. Methods Human nasal primary epithelial cells and a human alveolar epithelial cell line A549 wer...

WDR23 prevents bone loss by promoting autophagic degradation of TRAF6 in osteoclastogenesis

Tumor necrosis factor receptor-associated factor 6 (TRAF6) is a pivotal adaptor molecule in the receptor activator of nuclear factor-κB (RANK) and its ligand (RANKL) signaling pathways, which are essential for osteoclastogenesis. In this study, we identified WD40 repeat-containin...

A report of 35 unrecorded bacterial species belonging to the classes Alphaproteobacteria and Betaproteobacteria in Korea

This dataset contains the digitized treatments in Plazi based on the original journal article Jung, Hye Su, Yoon, Jung-Hoon, Joh, Kiseong, Seong, Chi-Nam, Kim, Won-Yong, Im, Wan-Taek, Kim, Myung-Kyum, Cha, Chang-Jun, Kim, Seung-Bum, Jeon, Che-Ok (2021): A report of 35 unrecorded...

Three-Year Outcomes of Drug-Eluting Stents, Drug-Coated Balloons, and Non-Drug-Eluting Devices in Native Femoropopliteal Artery Disease: An Analysis of the K-VIS ELLA Registry

Background: Although drug-eluting devices have demonstrated improved efficacy in femoropopliteal artery (FPA) disease, evidence on their long-term clinical outcomes in realworld practice remains limited.Methods: Using data from the multicenter Korean Vascular Intervention Society...

Unrecorded prokaryotic species belonging to the class Actinobacteria in Korea

This dataset contains the digitized treatments in Plazi based on the original journal article Kim, Mi-Sun, Jeong, Seong-Hwa, Kang, Joo-Won, Kim, Seung-Bum, Cho, Jang-Cheon, Cha, Chang-Jun, Im, Wan-Taek, Bae, Jin-Woo, Lee, Soon-Dong, Kim, Won-Yong, Kim, Myung-Kyum, Seong, Chi-Nam...

Discordant Antitumor Efficacy with Compromised Survival in High-Risk Unresectable Hepatocellular Carcinoma

Background/Objectives: Real-world data in high-risk patients remain limited; this study evaluated survival, safety, and prognostic factors in this patient group. Methods: This multicenter study retrospectively reviewed 783 patients who received Ate/Bev from 2022–2024 across South...

Cerebral Air Embolism Occurring During Percutaneous Endoscopic Gastrostomy

Air embolism is a rare but potentially fatal complication of gastrointestinal endoscopic procedures, primarily affecting the pulmonary circulation. Systemic air embolism, especially with cerebral involvement, is exceedingly uncommon. We report a case of cerebral air embolism that...

Serial Changes in CSF Volume Proportion on Brain CT and 6-Month Neurologic Outcomes After Cardiac Arrest: A 72–96-h Landmark Cohort Study

Background: Single-time-point cerebrospinal fluid (CSF) volume proportion (pCSFV) has shown limited prognostic utility after out-of-hospital cardiac arrest (OHCA). We hypothesized that serial within-patient change in pCSFV (ΔpCSFV), rather than absolute values, would reflect prog...

Spatial nonparametric Bayesian Poisson hurdle model for analyzing zero-inflated tick data

Abstract Severe fever with thrombocytopenia syndrome, an infectious tick-borne disease, has been increasingly reported in South Korea. Understanding the epidemiology of its vectors will help predict the spatio-seasonal abundance of ticks and manage future health risks related to...

Development and application of a two-dimensional numerical model for debris flow-induced impulsive wave considering debris flow erosion-entrainment process

Landslides and debris flows occurring in reservoir watersheds can generate tsunami-like waves by inflowing into the reservoir. When such disasters occur during periods of high-water levels, such as the flood season, overtopping due to waves is inevitable. Analyzing such events is...