Chungnam National University

Cytologically Suggested Vulvar Involvement in a Dog with Multicentric Lymphoma After a Nodal Response to CHOP-Based Chemotherapy, with Discordant Clonality Results: A Case Report

Involvement of the female reproductive tract is rare in canine lymphoma. A 9-year-old spayed female Maltese dog was presented with generalized lymphadenopathy. Cytology of a mandibular lymph node aspirate indicated large cell lymphoma, whereas PCR for antigen receptor rearrangeme...

Cell-Penetration Peptide-Conjugated Octominin II Hybrid Inhibits the Multidrug-Resistant Shigella flexneri

Background/Objectives: The genus Shigella is one of the major pathological agents responsible for diarrhea and diarrhea-related mortality worldwide. It shows a decreasing sensitivity to most conventional antibiotics available today. Methods: Hence, an antimicrobial peptide, Octom...

Structure-property relationships for catalyst design toward CO2 utilization via dry reforming of methane

Dry reforming of methane (DRM) utilizes CO 2 as a soft oxidant to convert CH 4 into synthesis gas, a versatile feedstock for downstream fuels and chemicals. However, practical CO 2 utilization through DRM is constrained by catalyst deactivation caused by metal sintering and carbo...

COSPEC: A Specification Elicitation Framework for Context Co-Construction with LLMs

Vibe coding uses repeated natural-language prompts and minimal code review in large language model (LLM)-based development. Development may end before sufficient client–LLM context co-construction occurs. We propose CO-constructed SPECification (COSPEC), combining Joint Applicati...

Expression of STAT3 and STAT6 in Men with Large Versus Small Prostates Undergoing Transurethral Resection of the Prostate

Background and Objectives: The factors driving variations in prostate size in patients with benign prostatic hyperplasia (BPH) remain unclear. We evaluated the differential expression of signal transducer and activator of transcription (STAT) 3 and 6 in patients with BPH and larg...

Ultrafast Magneto‐Geometric Control of Terahertz Helicity in Curved Ni Metasurfaces

ABSTRACT Dynamic helicity control in the terahertz (THz) regime is essential for ultrafast polarization optics, chiral spectroscopy, and polarization‐selective photonic devices, yet remains difficult because most THz chiral systems are structurally fixed or rely on slow external...

Non-Invasive Brain Stimulation for Central Neuropathic Pain: An Exploratory Randomized Sham-Controlled Crossover Trial

Background/Objectives: Central neuropathic pain (CNP) is difficult to manage, and comparative evidence for non-invasive brain stimulation is limited. We explored the short-term efficacy and safety of repetitive transcranial magnetic stimulation (rTMS) and transcranial direct curr...

Surface sulfur-modified NiO nanoparticles with enhanced oxygen evolution reaction kinetics and periodic electrochemical durability evaluation

Developing efficient and durable oxygen evolution reaction (OER) electrocatalysts is essential for sustainable hydrogen production through water electrolysis. Herein, pristine NiO nanoparticles and NiO–S composites containing 10 wt% (NiO@S1) and 20 wt% sulfur (NiO@S2) were prepar...

A Modular and Divergent Strategy for Dibenzo[ b,f ]oxepine Natural Products: Total Syntheses of Pacharin, Bauhiniastatins 1–4, and Bauhinoxepins C–J and Structural Revision of Bauhinoxepin F

Abstract We report the development of synthetic routes to representative Bauhinia family natural products, including pacharin, bauhiniastatins 1–4, and bauhinoxepins C–J. The key transformation involves a one-pot aldol condensation/SNAr sequence to efficiently construct the diben...

Comprehensive comparison of different structural thermal management systems for lithium-ion battery module based on electrochemical–thermal–aging and conjugate heat transfer coupled model

In this study, we extend the analysis of typical BTMS structures—traditionally focused on temperature-based thermal parameters—by incorporating electrochemical indicators such as SOC and SOH. Four structurally distinct BTMS configurations were evaluated in terms of fluid flow, th...

Kidney function-dependent plasma proteomic architecture of incident myocardial infarction: a proteome-wide association study of UK Biobank participants

Background: Individuals across the spectrum of kidney function experience excess risk of acute myocardial infarction (AMI), but whether the plasma proteome's association with this risk is itself modified by the estimated glomerular filtration rate (eGFR) remains uncharacterized....

Aggregate risk assessment of bisphenols A, S, and F among the general Korean population

Bisphenol A (BPA) and its substitutes Bisphenol S (BPS) and Bisphenol F (BPF) have been identified as endocrine-disrupting chemicals that affects reproductive functions. In Korea, BPA use has been restricted, resulting in increased utilisation of BPS and BPF as alternatives. Howe...

Variational Auto Encoder for automated structure segmentation of materials

Atomic-scale structural heterogeneity plays a crucial role in determining the properties of nanomaterials and complex energy systems. High-resolution STEM imaging provides critical insights into these structures, but conventional segmentation techniques often struggle with intric...

Effective power and energy utilization analysis of a dual-motor electric tractor under battery current limitations

This study evaluated the effective power and energy utilization characteristics of a dual-motor electric tractor under simultaneous power take-off (PTO) and traction operating conditions. Experimental measurements were conducted using Organization for Economic Cooperation and Dev...

Extracellular Vesicles, Exosomes, and Cancer: Detection and Therapeutic Monitoring

Abstract Extracellular vesicles (EVs) are membrane-bound vesicles released by cells into the extracellular space. Exosomes are a nanoscale subtype of extracellular vesicles (typically 30–200 nm) secreted by almost all types of cells. They carry a diverse molecular cargo, includin...

Pathological calcium overload impairs skeletal muscle regeneration through sustained NFAT-dependent proliferative signaling

Abstract Skeletal muscle regeneration requires coordinated myoblast proliferation and differentiation. Calcium dysregulation is commonly observed in aging and disease-associated muscle weakness; however, its impact on myogenic progression remains unclear. In this study, we invest...

Criteria-based probable REM sleep behaviour disorder and risk of Lewy body dementia: analyses of a memory clinic cohort and a community cohort

Abstract Background REM sleep behaviour disorder (RBD) is the strongest prodromal marker of alpha-synucleinopathies, but whether a brief questionnaire carries prognostic information for Lewy body dementia is unclear. We tested whether criteria-based probable RBD (pRBD)—a question...

Development and validation of VentPilot: an AI-based recommendation system for mechanical ventilation

BACKGROUND: Mechanical ventilation requires repeated adjustment to changing patient physiology, but consistent individualized management remains challenging. We developed VentPilot, an artificial intelligence-based system for recommending ventilator settings, and evaluated it in...

A report of 34 unrecorded bacterial species in Korea, belonging to the Actinobacteria

Ko, Kwan Su, Cha, Chang-Jun, Im, Wan-Taek, Kim, Seung-Bum, Seong, Chi-Nam, Bae, Jin-Woo, Jahng, Kwangyeop, Cho, Jang-Cheon, Joh, Ki-seong, Lee, Soon Dong (2017): A report of 34 unrecorded bacterial species in Korea, belonging to the Actinobacteria. Journal of Species Research 6 (...

Report of 21 unrecorded bacterial species in Korea belonging to the phylum Actinobacteria, discovered during the survey in 2020

Ham, You Ju, Jeong, Ji Won, Im, Wan-Taek, Kim, Won-Yong, Yoon, Jeong-Hun, Kim, Myung Kyum, Seong, Chi Nam, Kim, Seung Bum (2022): Report of 21 unrecorded bacterial species in Korea belonging to the phylum Actinobacteria, discovered during the survey in 2020. Journal of Species Re...