Chinese Academy of Agricultural Sciences

Reading immune restoration through Mycobacterium tuberculosis intrahost evolution

ABSTRACT Antiretroviral therapy (ART) suppresses human immunodeficiency virus replication, but does not fully restore protection against tuberculosis. The relevant mechanisms are still poorly understood. M. C. Chao, M. R. Chase, S. Wakabayashi, A. J. Vickers, et al. (mSystems 11:...

Rhizosphere microbiome-dependent metabolic reprogramming enhances potato salt tolerance in saline soils

Soil salinization is increasing globally, causing yield losses, especially in irrigated agriculture. Rhizosphere microorganisms can improve plant salt tolerance, but evidence in potato remains limited. In this study, rhizosphere microbial community diversity and structure differe...

Melanomacrophages exhibit FDC-like features: aquatic reovirus induces melanomacrophage death to suppress antibody responses

Genotype II grass carp reovirus (GCRV-II)-caused grass carp hemorrhagic disease severely restricts aquaculture, yet its adaptive immune evasion mechanism remains unclear. In mammals, follicular dendritic cells (FDCs) act as the core antigen-presenting cells that drive germinal ce...

Effects of Supplemental Drip Fertigation on Grain Yield and Water and Nitrogen Use Efficiencies of Spring Maize in the Dryland Farming Region of the Eastern Loess Plateau

Water–nitrogen mismatch constrains stable and resource-efficient spring maize production in the eastern Loess Plateau. A two-year field experiment was conducted in Jinzhong, Shanxi Province, China, during 2024–2025. Supplemental irrigation was applied three, four, or five times i...

Underground Signals: The Ecological Power of Root Volatiles

Root volatiles mediate diverse belowground interactions among plants, microbes, and invertebrates, but biological and environmental conditions strongly influence their production, movement, perception, and ecological effects. This review synthesizes current knowledge through an i...

Host-mediated insecticide sequestration in target-site-resistant pests impacts parasitoid fitness and evolution

Insecticide resistance poses a major challenge to global pest management, yet its cascading effects on ecological networks remain poorly understood. Here, we show that target-site-resistant herbivorous insects can accumulate unmetabolized insecticides and inadvertently function a...

A 6His-2Flag dual-tag strategy enables high-yield production of antimicrobial peptide N6 in Pichia pastoris to combat multidrug-resistant Klebsiella pneumonia

In response to the global threat posed by multidrug-resistant Klebsiella pneumoniae , this study established an efficient heterologous expression system for the antimicrobial peptide N6 in Pichia pastoris X-33. By employing an innovative 6His-2Flag dual-tag fusion strategy couple...

Unraveling umami and kokumi: taste characteristics and molecular mechanisms of milk-derived peptides

Although taste-active peptides have been isolated from enzymatic hydrolysates of defatted high-protein milk powder, their sensory properties, processing stability, and receptor-binding mechanisms remain largely unexplored. In this study, we synthesized milk-derived taste- active...

The gut microbiota of Brandt’s vole under varying population densities reveals contrasting patterns in the natural environment

The population density of rodents fluctuates due to intrinsic and extrinsic factors, inducing density-dependent effects on organisms and their habitats. The gut microbiota of herbivores plays a pivotal role in digestion, immunity, environmental adaptation, and host fitness. Crowd...

Evaluating the Resilience of Cold-Region Rice Varieties to Climate Variability and Change Using the BDH-Rice Model: A Case Study in the Sanjiang Plain

The Sanjiang Plain is a key cold-region rice production area in Northeast China, where climate variability and warming may alter the adaptability and yield stability of rice varieties. Identifying varieties with both high yield potential and stable performance under current and f...

Genetic Variation and Haplotype Structure of CFAP299 and PRDM8 Associated with Fiber Yield and Hair Length Traits in Tianzhu White Yak

Fiber yield and hair length are important economic traits in Tianzhu White Yak. However, the genetic variants associated with fiber production performance in this breed remain insufficiently characterized. This study aimed to investigate the associations of single nucleotide poly...

Dietary Fermented Mulberry Leaf Triggers Dose-Dependent Changes in Growth, Antioxidant Immune Status and Intestinal Microecology of Amur Sturgeon (Acipenser schrenckii)

Mulberry leaf is a promising sustainable plant-based feed resource; however, high dietary inclusion of raw mulberry leaf impairs growth in carnivorous fish. Fermentation degrades anti-nutritional components and enhances nutrient availability, yet the dose-dependent effects and un...

Natural variation in GmSOP5 regulates seed oil and protein content during soybean domestication

ABSTRACT Seed oil content, protein content, and yield are agronomically important, correlated traits that determine the economic value of soybean ( Glycine max ). However, improving seed quality and yield simultaneously is challenging because gains in one breeding target often co...

GloSVeT: a global 0.05° monthly mean surface soil and vegetation component temperature dataset (2003–2023)

Current satellite-derived land surface temperature (LST) products represent a mixed radiative signal that integrates soil and vegetation contributions, obscuring the physical mechanisms controlling surface energy partitioning and ecosystem functioning. To overcome this limitation...

Effects of Supplementary Fertilization on Physiological Traits and Yield of Soybean Following Drought-Flood Abrupt Alternations of Varying Intensities

Drought-flood abrupt alternation (DFAA) events severely constrain soybean production, yet the physiological effects of supplementary fertilization and other measures following such events are unclear. This study investigated the effects of supplementary fertilization (SF) on the...

Fgk3 interacts with FgMetR to regulate mycelial growth, conidia development, DON production, and pathogenicity in Fusarium graminearum

Abstract Glycogen synthase kinase-3 (Gsk3) is a potential drug target in human medicine, controlling many substrates in cellular processes. In this study, FgMetR was identified as a putative binding partner of Fgk3, the Fusarium graminearum ortholog of Gsk3, although the specific...

Comprehensive Benggang control promotes the recovery of soil organic carbon fractions and carbon sequestration potential

Benggang is a severe collapsing-gully erosion landform in the granite-derived red-soil region of southern China. Although comprehensive Benggang control integrating engineering measures, vegetation restoration, and management has improved the erosion environment and promoted vege...

Dual Roles of RAD23b and RAD4 on the Desiccation Tolerance of Germinated Seeds

Desiccation tolerance (DT) is a survival trait enabling orthodox seeds to withstand extremely low water content. While some protective factors are characterised, it remains mechanistically obscure. Here, based on PEG-induced DT re-establishment in germinated Brassica napus L. see...

MiniSdd7‐Derived Cytosine Base Editor Promotes Efficient Multiplex Gene Knockout in Porcine Primary Fibroblasts

ABSTRACT Efficient multiplex genome editing is essential for improving complex traits in livestock that are governed by multiple genes. However, achieving high‐efficiency simultaneous editing at multiple loci remains challenging for cytosine base editors (CBEs), largely due to va...

African swine fever virus pMGF110-9L plays a critical role in the integrated stress response and viral pathogenesis

African swine fever virus (ASFV) is the causative agent of ASF, a highly contagious and frequently fatal hemorrhagic disease in domestic swine and wild boars, posing a significant threat to the global pig industry. To ensure successful replication, ASFV may modulate cellular stre...