China Medical University

Sulfated PSGL-1 primes the enterovirus A71 fivefold vertex for localized remodeling

Enterovirus A71 (EV-A71) causes hand, foot, and mouth disease and poses a significant public health threat through severe neurological complications in pediatric cases. P-selectin glycoprotein ligand-1 (PSGL-1) functions as an attachment factor, yet the structural basis of PSGL-1...

Martian‑Regolith Simulant Confined Nanogenerators for Wireless Tactile Sensing for Human‐Machine Interface

Achieving a sustainable energy system for space missions remains challenging due to the continued reliance on Earth-supplied materials. This underscores the importance of in situ resource utilization (ISRU) strategies that convert planetary resources into functional electronic co...

Exosomes as Emerging Therapeutic and Diagnostic Platforms: Biological Functions, Clinical Applications, and Translational Challenges

Exosomes are small membrane-bound extracellular vesicles of endosomal origin that play pivotal roles in intercellular communication by transferring proteins, lipids, metabolites, and nucleic acids. Increasing evidence indicates that these vesicles participate in diverse physiolog...