Aix-Marseille Université

Measuring masses of transiting Earth-like planets: first insights from the PLATO RV Data Challenge

Abstract The PLATO Stellar Variability Mitigation Working Group designed a radial-velocity (RV) data challenge to assess the precision and accuracy achievable on RV semi-amplitudes in the context of the future PLATO follow-up. Using Sun-as-a-star observations obtained with HARPS-...

High‐Detectivity InGaAs/GaAsP Superlattice PIN Photodetector with a Thin Absorber on GaAs substrate for 1100 nm Applications

ABSTRACT III‐V materials exhibit superior optoelectronic properties compared to conventional semiconductors, making them ideal for short‐wavelength infrared (SWIR) photodetectors. These devices are in demand for applications such as telecommunications, LiDAR, and biomedical engin...

An Optimal Spray Device for the Nose-to-Brain Delivery of AmyP53, an Adaptive Therapeutic Peptide for Alzheimer’s and Parkinson’s Diseases

Background: Nose-to-brain delivery offers a noninvasive route to bypass the blood–brain barrier for the treatment of neurodegenerative diseases. AmyP53 is a first-in-class adaptive 12-mer peptide that prevents the formation of neurotoxic amyloid oligomers by competitively targeti...

Zippers and Twisters: Planes of Satellite Galaxies Emerge from Whirling and Shocking Gas Streams in the Cosmic Web

Abstract We investigate dwarf satellite systems around massive centrals analogs (Milky Way to Centaurus A) in the NewHorizon simulation. Using simple estimators limiting overdetection, we identify planes of satellites comparable to observations in 30%–70% of cases. The full sampl...

Nuclear activities and interactome of the NS5 protein of tick-borne encephalitis virus

Orthoflaviviruses are RNA viruses responsible for significant diseases in humans, domesticated animals, and wildlife. Their NS5 protein is central in viral replication, functioning both as an RNA-dependent RNA polymerase and a methyltransferase, while also modulating cellular pro...

Characterising recent antimalarial resistance in West Africa: Insights from amplicon sequencing of 17,384 Plasmodium falciparum infection samples

<ns5:p> Background <ns5:italic>Plasmodium falciparum</ns5:italic> ( <ns5:italic>P. falciparum</ns5:italic> ) infection remains a significant public health threat in West Africa, where chemoprevention and first-line therapies are key interventions against malaria. However, the dev...

Budigalimab: a viable option for patients with advanced solid tumors

INTRODUCTION: Immune checkpoint inhibitors transformed lung cancer treatment and prognosis, new drugs are currently being developed to continue to improve patient's outcome and especially surrogate immune checkpoint for each pharma company pipeline. AREAS COVERED: We conducted a...

Effectiveness of health mediation to promote organised cancer screening among underserved and under-screened populations in Marseille, France: findings from a repeated cross-sectional survey

Abstract Background Since 2022, the “13 en Santé” health mediation program has been implemented in Marseille, France, to reduce social health inequalities, in socioeconomically disadvantage neighbourhoods, with a particular emphasis on promoting participation in population-based...