A randomized trial found the largest reductions among younger children and those who were most anxious to begin with.
Researchers conducted a randomized controlled trial involving 80 children and their caregivers at one medical center. Children were assigned either to use the MuMa interactive music tablet before surgery or to receive standard care.
The tablet reduced children’s preoperative anxiety by 38% compared with standard care. The researchers reported no clinically relevant differences in the trial’s secondary outcomes, which included heart-rate variability, cooperation during anesthesia induction, postoperative agitation and later behavioral changes.
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Scientific Reports · 2026 · DOI: 10.1038/s41598-026-66888-1
Authors: Roland Imle, Ann-Sophie Wiemer, Katharina Hartwig, Christiane Hillebrenner, Stephan Vedder, Sven F. Garbade, Christina Blume, E. Willuth, Thomas Mueller, Mira Boos, Julian Koenig, Dorothee von Moreau, Patrick Guenther, Philipp Romero
Institutions: University of Cologne, University Hospital Cologne, Heidelberg University, University Hospital Heidelberg, German Cancer Research Center, Universität Hamburg, Heidelberg Institute for Theoretical Studies, Hamburg University of Music and Drama