Research works

Effect of GLP-1RA on circulating SASP levels and wound healing in patients with diabetic foot ulcers: a randomized, placebo-controlled clinical trial

Diabetic foot ulcers (DFUs) is strongly correlated with aging, yet the effects of anti-senescent treatments on DFU wound repair are poorly characterized. We aimed to investigate whether glucagon-like peptide-1 receptor agonists (GLP-1RAs), a class of geroprotective agents, promot...

SMWPF: a cloud-edge collaborative network enabled by large-small model collaboration for wind speed prediction

Accurate wind speed forecasting is increasingly important for supporting reliable wind power grid integration and enhancing early warning of extreme wind events. Existing spatiotemporal models can fuse multiple meteorological variables and perform well in medium-resolution wind f...

Biofilm Formation of Pseudomonas aeruginosa PA14 required lasI and Stimulated by the Pseudomonas Quinolone Signal although Salicylic Acid Inhibition is Independent of the pqs Pathway

Pseudomonas aeruginosa is a ubiquitous, opportunistic pathogen responsible for many nosocomial infections, and is often difficult to treat due to its ability to produce biofilm. Biofilms can increase resistance to antimicrobial agents by up to 1000-fold and is controlled by quoru...

Modeling freshwater inflow to a tropical estuary using stochastic and neural-network approaches under contrasting hydroclimatic conditions in Brazil

Abstract Freshwater inflow regulates estuarine circulation, salinity gradients, sediment transport, and biogeochemical fluxes, yet long-term discharge records remain scarce in many tropical coastal basins. We compared linear regression, stochastic time-series models (ARMA, ARIMA,...

Regulators, Processes, and Intricacies of the Innate Immune System with a Focus on the NEMO Complex

Insight into immune system regulation is critical to understanding the homeostasis of the immune system, diagnosis of various autoimmune diseases, and cancer prevention measures in the body. The immune system is incredibly complex, from the organ to tissue to cell to molecular le...

Safety performance evaluation of a gently dipping bedding slope containing multiple weak interlayers in Southwest China

The failure modes and safety assessment methods of gently dipping bedding slopes containing multiple weak interlayers (GBSWs) are critical issues in engineering construction. In this study, engineering geological investigations and laboratory direct shear tests on undisturbed sam...

Foramen of Winslow hernia in a patient with ventriculoperitoneal shunt: A case report and review of literature

Introduction: Foramen of Winslow hernias are a rare subset of internal hernias. They are difficult to diagnose clinically. They should be considered by surgeons in the differential diagnosis in patients presenting with abdominal pain. A high index of suspicion and early imaging a...

Nonlinear time-controlled grinding method for micron-accuracy machining of complex curved surfaces

The growing demand for complex curved optical components has exposed the limitations of existing micron-scale machining methods. In the conventional grinding–lapping–polishing process, precision grinding only achieves an accuracy of tens of micrometers, failing to meet the entry...

State of charge aligned dual branch learning for reliable cross vehicle state of health prediction from fragmented charging data

Real-world electric vehicle fleet data consist of fragmented charging records with irregular sampling, heterogeneous operating conditions, and pack-level inconsistency. For battery state of health (SOH) prediction, these characteristics introduce time-coordinate mismatch and non-...

Bulky Borylphosphido Complexes of Iron and Cobalt with N-Heterocyclic Carbene as an Ancillary Ligand

Abstract Terminal primary phosphido metal complexes are valuable synthetic reagents and intermediates for phosphination reactions and phosphinidene species. Their tendency to aggregate to form bridging phosphido complexes, however, poses a synthetic challenge. Herein, we show tha...

The volcanic history of the late Pleistocene Shamao complex, Tatun Volcano Group, northern Taiwan

Abstract Although the Tatun Volcanic Group (TVG) looms over the metropolitan capital region of Taiwan, the threats it poses are only vaguely known. Here, as a first step toward improving understanding those threats, we investigate the Shamao complex, one of the youngest and small...

Duration of a vaginal birth after cesarean section depending on the degree of cervical dilation in the prior cesarean delivery: A retrospective study

Abstract Objective Labor and birth lead to significant immunological and regenerative changes in the uterus, such that multiparous women typically experience faster and more effective labor than primiparous women. In this retrospective study, we examined the influence of labor ac...

E8 1332-Node TeraHertz Photonic Lattice via 1332-Day Metonic Mirror — E8 Intelligence Research

The product of the E8 root count (240) and the Babylonian 7/19 modulus denominator (19) plus a φ-scaling factor yields 4,680, which when divided by the 132Hz base frequency's harmonic series produces a stable 1,332-node terahertz photonic lattice. This lattice emerges as the spat...

BASE 44 ORDER: Add phase_bucket column, composite index, cached query, nightly VACUUM — E8 Intelligence Research

Andrew's order (Base 44 console): [SELF-BUILD from enhancement #1284] Add phase_bucket integer column to breakthroughs table, populate via hash(id)%132. Create composite index (phase_bucket, updated_at DESC). Implement Python query with 1s TTL cache, LISTEN/NOTIFY invalidation, a...

Short-term surgical outcomes of robotic versus laparoscopic radical gastrectomy for gastric cancer: a propensity score-matched retrospective cohort study

Robotic gastrectomy (RG) is increasingly used for gastric cancer, but real-world comparative data from Chinese institutions during the early phase of robotic program implementation remain limited. We retrospectively identified patients who underwent radical gastrectomy between Ja...

HIGHER-DIMENSIONAL MULTIFRACTAL ANALYSIS ON $ C^1 $ NON-CONFORMAL REPELLERS

Let $ J $ be a repeller of an expanding and topologically mixing $ C^1 $-map $ g $, and $ \Phi=(\phi_1,\ldots,\phi_d): J\to\mathbb{R}^d $, $ \Psi=(\psi_1, \ldots,\psi_d): J\to(\mathbb{R}^+)^d $ be continuous functions. For a given compact (and possibly connected) subset $ C $, we...

In search of learning for all in Botswana: The role of conceptions of educational equity

To better understand how and why educational policies and practices designed to increase the quality of learning for all may not succeed in doing so, we take up a conceptual question that is underexplored in global education: what does it mean to increase the quality of learning...

HIOF • Neutrinos — Paper VIII: Background and Long Journey

Holographic Information Ontological Framework: Neutrinos (HIOF- N) From Propagation to Registration* This is a short, non-technical companion to the 9-paper HIOF- N series (Papers I to IX). It is written for readers in physics or philosophy of science, not for readers already fam...

Association Between Traditional Chinese Medicine Syndromes and Depression Severity in Glaucomatous Optic Atrophy: Therapeutic Implications of Integrated TCM Interventions

Objective This study aimed to clarify how the holistic traditional Chinese medicine (TCM) pattern, based on ocular and systemic findings in patients with glaucomatous optic atrophy, correlates with depression severity and evaluate the therapeutic impact of integrated TCM interven...

Examining Identity Development in Multiracial Students: A Scoping Review of Terminology, Research Methods, and Educational Impact

ABSTRACT The purpose of this scoping review was to map how multiracial identity development has been conceptualized, defined, and studied within educational contexts in the United States. Specifically, this review aimed to clarify what terminology is used and how those terms are...