Research works

Effects of Salinity on Bacterial Spot Disease, Physiology, Growth, Fruit Quality, and Transcriptomic Responses in Tomato Plants

Soil salinity and bacterial spot of tomato (BST), caused by Xanthomonas perforans, are major abiotic and biotic stresses limiting tomato production, particularly in Florida. While their individual effects are well documented, the impact of soil salinity on BST has not yet been in...

Efficacy and Cost-Effective Treatment of Isometric Resistance Training for Blood Pressure Control: A Narrative Review in Healthy Individuals and People with Cardiovascular Diseases

Background: Isometric resistance training (IRT) has emerged as a promising non-pharmacological intervention for blood pressure (BP) management. Although current hypertension guidelines primarily recommend aerobic and dynamic resistance exercise, growing evidence indicates that IR...

Targeting Bioenergetic, Redox and Prostaglandin Pathways in Long COVID-Associated Post-Exertional Malaise and Brain Fog: A Nutraceutical Translational Hypothesis

Post-exertional malaise (PEM) and cognitive dysfunction (“brain fog”) are among the most disabling features of Long COVID, yet approved disease-modifying treatments remain lacking. Emerging evidence implicates interacting disturbances in mitochondrial bioenergetics, redox regulat...

Soil Microbial Co-Occurrence Networks Along a Grassland Degradation Gradient: Nonlinear Thresholds, Divergent Bacterial–Fungal Responses, and Environmental Drivers

Grassland degradation is a global ecological crisis that profoundly alters aboveground vegetation and soil properties, yet its impacts on soil microbial co-occurrence networks remain poorly understood. Here, we investigated soil bacterial and fungal communities along a well-defin...

Are circular innovations disruptive? An analysis of the role of inventor networks in the European semiconductor industry

The expansion of advanced technologies is intensifying demand for energy, materials, and efficiency of production systems, with semiconductors exemplifying the tension between rapid technological progress and resource sustainability, and the development of circular innovations. Y...

Experimental Results of A Novel Two-Phase Water Ejector Design for High-Temperature Heat Pump Applications

Abstract High-temperature heat pumps (HTHPs) are a key technology for decarbonizing industrial process heat. Within such systems, two-phase water ejectors offer a promising opportunity to function as secondary steam compressors. By entraining hot steam with high-pressure water, t...

Modulation of gastric activity using appetizing and disgusting images.

Interoception is the nervous system’s integration of internal bodily signals, including gastrointestinal inputs. This process is crucial for regulating homeostasis, cognition and emotion, and depends on bidirectional brain-body communication. Given recent evidence of brain-stomac...

CODEX RERUM: The Spiral of the Resonance: Universal Treatise on the Mechanics of the Entity and the Persistence of Matter

This treatise unifies the five foundational pillars of the Mathematics of Persistence, defining a closed and coherent logical metasystem based on the Axiom of the Inviolability of the Entity. Through the Postulate of Operator Decay (N ÷ 0 ≡ N ), the asymptotic singularity of the...

Phylogenetic structure of conifers in regional floras in relation to climate and environmental heterogeneity worldwide

Despite having only about 670 species worldwide, conifers are one of the ecologically and economically most important plant groups. They have a rich fossil record and previous studies have shown that their current diversity is the result of past radiations, extinction, and disper...

Impaired effort perception, not reward sensitivity, impacts the effort-reward trade-off in Parkinson’s disease

Deciding whether and how to act depends on a trade-off between the effort required to execute a given action and the potential reward for completing it. Impairments in this effort-reward trade-off have been proposed to underlie reduced movement vigor, or bradykinesia, in Parkinso...

Two Earliest Optical-UV Tidal Disruption Events Hidden in the SDSS DR7 Catalog Unveiled by the Transformer-based Spectrum Classifier

Abstract Optical spectroscopic features are decisive in the current identification of optical-UV tidal disruption events (TDEs). Regarding that the TDE estimated occurrence rate is 10 −5 –10 −4 galaxy −1 yr −1 by both theoretical and observational methods, large optical spectrosc...

Genetic Diversity and Hospital Circulation of Opportunistic Pathogens in COVID-19 ICUs: Whole-Genome Sequencing Data

The COVID-19 pandemic led to a dramatic increase in healthcare-associated infections and antimicrobial resistance, particularly in intensive care units (ICUs). The aim of this study was to provide a comprehensive genomic characterisation of all clinically significant opportunisti...

PFUSRC-080 Topological Morphogenesis of the Collatz Conjecture — From 3n+1 Iteration to 45° Biconical Interlayer Oscillation: Tracing a Number-Theoretic Problem to Its Geometric Boundary

The Collatz conjecture (3n+1 problem) is a classic unsolved problem in number theory. Its iteration rule is: for any positive integer n, if n is odd, map n \to 3 n+1; if n is even, map n \to n / 2. The question is whether repeated iteration necessarily converges to 1 for all init...

Fatigue Induced by Walking Uphill and Downhill Similarly Disrupts Postural Balance but Their Disruptive Factors Differ

Background/Objectives: Walking-induced fatigue disrupts postural balance, but the differentiated effects of walking uphill and downhill remain unclear. The aim was to compare the impact of two walking sequences, either uphill (+10%) or downhill (−20%), with an identical number of...

Quasi-Random Sampling-Enhanced Metaheuristic Algorithms for CAMD-Based Solvent Selection in Octacosanol Extraction

This study develops a computer-aided molecular design (CAMD) framework to select solvents for extracting octacosanol from multicomponent sugarcane wax. The solvent-selection problem is formulated as a mixed-integer nonlinear programming problem in which candidate solvents are gen...

Endogenous Neurotoxicity: A Pathophysiological Consequence of Homeostatic Dysfunction

Neurotoxicity is generally thought to result from exogenous agents like environmental chemicals, drugs and biological toxins. However, increasing evidence suggests that many endogenous molecules that play a critical role in normal brain function can become neurotoxic when the reg...

From real-world events to open POI data: a measurement protocol for time-to-reflection, with a benchmark from Japanese official registers

Background Open point-of-interest (POI) datasets increasingly carry temporal fields—Foursquare OS Places attaches creation and closure dates to over 100 million places and feeds Overture Maps—inviting longitudinal research that depends on a quantity never systematically measured:...

PFUSRC-066 The Origins of Mass: From Breaking to Topological Latching — A Repositioning of the Higgs Mechanism within the PFUSRC Framework

The Standard Model of particle physics relies on the Higgs mechanism and spontaneous symmetry breaking to fit elementary particle masses, yet it has an inherent ontological blind spot. It fails to explain the generative origin of symmetry breaking and cannot unify spontaneous and...

Valuation Boundaries in Monetary Ecosystem Service Assessment: A Logic-Chain-Based Reporting Framework with a Vineyard Application

Monetary ecosystem service (ES) valuations often differ across studies even when similar methods are applied because available data implicitly determine which biophysical, management, and demand-side drivers are represented. These implicit “valuation boundaries” are rarely report...

Facile synthesis of platinated DNA nanoparticles with radiosensitizing potential

DNA nanostructures are promising drug delivery platforms but often suffer from limited structural stability and high production complexity. Cisplatin can cross-link DNA and act as a therapeutic agent, offering a simplified approach to stabilize DNA nanostructures while incorporat...