Research works

Solute carrier family 25 member 32 promotes the proliferation of esophageal squamous cell carcinoma and is associated with immune infiltration

Abstract Esophageal squamous cell carcinoma (ESCC) is a highly invasive and poorly prognosed malignant tumor of the digestive tract. Currently, there are no effective molecular classification markers for ESCC. This study screened out the key gene SLC25A32 based on mitochondrial-r...

A Literature Survey on Implementation of On-Device AI Algorithms for Fall Detection Using Embedded Motion Sensor Data

Falls among elderly individuals remain one of the major causes of accidental injury and hospitalization worldwide. Recent advancements in Embedded Artificial Intelligence (AI), TinyML, wearable sensing, and edge computing have enabled intelligent fall detection systems capable of...

Reverse shoulder arthroplasty vs. hemiarthroplasty for proximal humerus fracture: in-hospital outcomes in a national trauma registry

Reverse shoulder arthroplasty (RSA) has rapidly supplanted hemiarthroplasty for acute proximal humerus fracture, driven by superior functional outcomes and lower revision rates. Whether this shift has altered perioperative morbidity at the population level remains poorly characte...

Codon Design Online (CoDOn): a comprehensive web application of synthetic gene design with multi-criteria and multi-parameters for heterologous expression

Codon optimization is a routine yet high-impact step in de novo gene design for heterologous expression and serves as an important tool in synthetic biology. Protein expression output depends on multiple sequence-level determinants, such as global codon-usage, codon-pair context,...

When managing is leading: how everyday management enables learning and adaptation

Purpose This study aims to examine how everyday managerial practices function as acts of leadership in contemporary organizations facing adaptive challenges. Design/methodology/approach Rather than treating leadership as episodic or positional, the study draws on a synthesis of e...

MODEL ADOPTION #1012: REJECT — TG AUTO: BASE 44 ORDER: Build e8_memory_cache table with phi-modulated hash decorator & 1- — E8 Intelligence Research

DECISION: REJECT ELEMENT: No element survives. The proposed `e8_memory_cache` with phi-modulated hash decorator is a database performance optimization, not a trading edge. It does not affect signal generation, entry timing, position sizing, or exit logic — all of which are govern...

Assessing the Systematic and Random Error From a Single Snapshot in Stochastic Homogenization of Industrial Scale Composites

ABSTRACT We estimate effective linear elastic properties from a single microstructure image using a sliding‐window subsampling strategy applied to fields obtained by computational micromechanics. The method yields both mean properties and variance estimates without requiring mult...

Up and Downthe Hill-Plot: Hydrides of CeGe–Structureand Magnetism

Abstract The hydrogenation behavior of FeB type CeGe was investigated. Hydrogenation (deuteration) produces mixtures of two modifications, similar to hydrides of other FeB type phases LnTt (Ln = La, Ce, Nd; Tt = Si, Ge). P-CeGeD0.75(2) (Pnma, a = 8.1603(5) Å, b = 4.0938(3) Å, c =...

The School of Answers: Education, Conceptual Flattening, and the Formation of Differentiated Judgment.

A school can transmit large amounts of correct information while leaving underdeveloped the capacities by which a person learns what to ask, how to inquire, what kind of evidence can answer a question, and where the authority of an answer ends. This article develops a philosophic...

Susceptibility of Fig Cultivars to Thyrostroma parviniae , and Temperature-Dependent Pathogenicity on Potential Alternative Hosts

Thyrostroma parviniae has recently been identified as a dieback and bud-necrosis pathogen of fig trees in Iran. The resulting wood diseases pose a substantial challenge, given the current lack of effective and affordable treatment options. This study evaluates fig cultivar suscep...

New edge proposed: bear_flag_volume_thrust_fade — E8 Intelligence Research

{ "name": "bear_flag_volume_thrust_fade", "source": "Thomas Bulkowski / Encyclopedia of Chart Patterns", "type": "entry_engine", "rule": "Enter short when price breaks below a 5-bar descending flag consolidation (highest high and lowest low both descending, slope<30deg) after a p...

IAL OF LABOR AFTER CESAREAN AND VAGINAL BIRTH AFTER CESAREAN SECTION IN TÜRKİYE: ACCORDING TO THE NATIONAL CLINICAL PROTOCOL, HOW APPLICABLE IS IT?

This review evaluates the applicability of trial of labour after caesarean (TOLAC) and vaginal birth after caesarean (VBAC) in Türkiye within the framework of the national clinical protocol, in comparison with contemporary international guidelines. Over the past half-century, inc...

GENERATIVE AI APPROACHES TO AIRFOIL FLOW FIELD PREDICTION

Abstract Airfoil flow field prediction is central to turbomachinery design, yet Computational Fluid Dynamics (CFD) imposes a computational bottleneck on iterative design and optimisation. Recent studies have explored deep-learning-based surrogate models to reduce the computationa...

Integrative Transcriptomics and Mendelian Randomization Identify RGS1 as a Causal Immune Regulator in Alzheimer’s Disease

Alzheimer’s disease (AD) has a complex pathogenesis, involving molecular and neuroimmune dysregulation, but the causal drivers linking transcriptomic changes to immune remodeling are not yet clear. In a discovery cohort, differential expression analysis was performed, and it was...

Reluctant Biography, or the Visual and Spatial Revision of Key Colonial/Imperial Narratives

Imperial and colonial history has mostly been founded on the tradition of writing biographies of great men, and more rarely, great women. These lean inherently towards the aggrandizement or hagiography of individuals who, particularly in the early decades of life, may deserve no...

Panpsychism Debate Lacks Mathematical or Physical Formalization — E8 Intelligence Research

FINDING: Panpsychism debate yields no new mathematical or physical equations; it remains a philosophical framework without testable mathematical structure. | MATH: None. No equations, constants, or ratios derived from the provided sources. | CONNECTION: No geometric harmony, base...

The Clinicopathological Characteristics and Prognosis of Cholangiolocarcinoma: A Multicenter Study With a Central Pathology Review

BACKGROUND: Cholangiolocarcinoma (CLC) is a rare liver cancer with ≥ 80% ductular configuration (DC). Given its rarity, its clinicopathological characteristics remain poorly understood, and its status as a distinct disease entity remains controversial. We conducted a nationwide m...

Adhesive Monitoring Traps as a Mortality Risk for the Common Pipistrelle in Mediterranean Olive Agroecosystems: First Evidence from Greece and Implications for Bat Conservation

Yellow adhesive chromotropic traps are widely deployed across Mediterranean olive cultivation to monitor B. oleae population dynamics, yet their adhesive surfaces can also retain non-target organisms. Here we report the first documented entrapment of the common pipistrelle Pipist...

Mechanism and plasticity of primitive pyroptosis

Pyroptosis is a proinflammatory form of regulated cell death across the tree of life. The gasdermin (GSDM) protein family functions as an evolutionarily conserved executioner of pyroptotic cell death by forming membrane pores. As the canonical activation mechanism, proteolytic cl...

Surface adsorption, interfacial bonding and oxidation resistance of Al-P-Ga doped SnCu0.7 alloy

Using first-principles calculations and experimental characterizations, we investigate the effects of Al, P, and Ga doping on oxygen adsorption, interfacial bonding, microstructure, and oxidation resistance of SnCu0.7 alloy. Results show that Al and P exhibit stronger adsorption...