Research works

AI-Enabled Performance-Based Procurement and Life-Cycle Maintenance of Highway Bridges: Integrating Single-Bid Risk Analytics and PPP Payment Optimization

Abstract Aging bridges, tight budgets, and procurement inefficiencies require a data-driven approach to maintenance contracts. Existing evidence shows that information and communication technology (ICT)–based construction management improves site productivity but remains unevenly...

Beyond AI-Generated Text: Strengthening Academic Integrity and Critical Thinking in Higher Education

The increasing use of Generative Artificial Intelligence in Higher Education has created new challenges for academic integrity, intellectual authorship, and the development of critical thinking. This study analyzes these challenges and evaluates a pedagogical intervention designe...

The Hsd17b13P260S patient variant knock-in male mouse model provides translational insights into HSD17B13 biology

Background Metabolic dysfunction-associated steatotic liver disease (MASLD) is a prevalent liver disease that can progress to metabolic dysfunction-associated steatohepatitis (MASH), a condition marked by inflammation and fibrosis that increases the risk of cirrhosis, liver failu...

Field performance evaluation of comminution and gravity processing circuits for artisanal saprolite gold ores

Abstract Artisanal and Small-scale Gold Mining (ASGM) operations increasingly adopt mechanized comminution, assuming it universally improves gold recovery. This case study challenges that generalized approach through a comparative field performance evaluation of two gravity recov...

Sucralose Alters Gut Microbiota, Intestinal Metabolites, and Epithelial Serotonergic Responses to Visceral Stimulation in Mice Exposed to Chronic Restraint Stress

Background/Objectives: Dietary modifiers of the gut ecosystem may influence intestinal and host responses associated with psychological stress. However, it remains unclear whether sucralose, a widely consumed non-nutritive sweetener, alters host–microbiota interactions following...

Congenital cervical pathologies in the saber-toothed cat Smilodon fatalis and the cave bear Ursus spelaeus – Nearing extinction in Late Pleistocene times

Inbreeding is a known cause for an increased incidence of vertebral malformations. Inbreeding can be the result of geographical isolation of a diminishing wild population. A high incidence of transitional vertebrae has for example been reported in declining, inbred populations of...

Keep your eye on…

…the value of health courses on substance use …parent bonding, mental health challenges during NICU stays

Mechanistic insights into cooperative permeation of glycerol and water through human aquaporin-10

Human aquaporins are integral membrane proteins that facilitate transmembrane transport of small molecules. Among the 13 members of this family, pH-regulated human aquaporin-10 (hAQP10) plays a critical role in glycerol metabolism and lipid homeostasis. A molecular-level understa...

Trace element accumulation in hooded crow nestlings: tissue- and age-specific patterns and implications for avian biomonitoring in riverine wetlands

Abstract Floodplain wetlands are dynamic ecosystems that may receive pollutants transported from upstream areas, but local exposure of wildlife to trace elements can vary depending on hydrology, bioavailability, habitat structure, and diet. In this study, we assessed the concentr...

An Ejector Refrigeration and Humidification–Dehumidification Desalination Hybrid System for Ceramic Industry Waste Heat Recovery: Performance Evaluation and Parametric Analysis

The sustainable development of the ceramics industry is severely impeded by its intensive energy consumption and the concomitant deficits in cooling and freshwater resources. To address these bottlenecks, this study proposes an integrated ejector refrigeration (ER)–humidification...

Operational Diagnosis and Data Suitability Assessment Using BMS and Smart-Meter Data in a Multi-Zone University Building

Aggregate building indicators can obscure substantial differences in electrical demand and thermal operation among monitored spaces. This case study examined 89 days of one-minute building management system (BMS) and smart-meter records from a multi-zone university building. Rout...

Knowledge-guided reinforcement learning for self-adaptive software engineering and multi-objective quality optimization

The current software engineering field is experiencing growing pressures due to the complexity of software systems, rapidly changing requirements, and high-quality expectations in a dynamic environment. Conventional development and quality assurance strategies are usually inflexi...

Cryo-EM structure of the bicarbonate receptor GPR30

G-protein-coupled receptor 30 (GPR30) is a bicarbonate receptor that plays a vital role in cellular responses to extracellular pH and ion homeostasis. Despite its significance, the mechanisms by which GPR30 interacts with bicarbonate ions remain elusive. There is no consensus on...

Weak Ridge-Flow Prior-Guided Fingerprint Reconstruction Under Severe Degradation

Fingerprint enhancement plays an important role in recovering identity-related ridge structures from degraded fingerprints. However, existing methods primarily focus on local texture restoration and may struggle to preserve ridge continuity and structural consistency under severe...

Aqueous Humor Proteomics Reveals the Molecular Basis for Differential Treatment Responses in nAMD and pmCNV

Purpose: Choroidal neovascularization (CNV) causes vision loss in neovascular age-related macular degeneration (nAMD) and pathologic myopia-related CNV (pmCNV). Despite shared clinical features, they respond differently to treatment. This study compared aqueous humor (AH) proteom...

Beyond the Nucleus: A Physical and Theoretical Analysis of the Fifth Dimension's Impact on Matter Stability and Nuclear Energy

This paper explores a theoretical framework examining the influence of a hypothetical fifth dimension on the stability of matter and nuclear energy dynamics. By integrating higher-dimensional concepts with nuclear physics principles, this study investigates how extra-dimensional...

Geochemical Effects of Groundwater Interaction with Steel Slag Aggregate Used in Road Construction

:This study assessed the effects of groundwater interacting with aggregate produced from steel slag, used as a ballast material in a waterproofing system protecting the road surface under high groundwater table conditions. Field investigations were carried out, with hydrochemical...

PRECISE-LLM: Formal Ambiguity Detection and Interpretation Enumeration for Text-to-SQL

Large language models translate natural-language questions into SQL with remarkable fluency, but they fail silently on ambiguous questions: rather than signalling uncertainty, the model commits to one reading and returns a syntactically perfect yet semantically wrong query. We pr...

A PHARMACEUTICAL AND ANALYTICAL STUDY ON DADRUHARA MALAHARA PREPARED WITH SOMRAJI TAILA

Background: Ayurvedic pharmaceutics includes various dosage forms intended for external application. Dadruhara Lepa is an external formulation used in the management of skin disorders, while Malahara Kalpana provides a semisolid dosage form suitable for convenient application and...

Synergistic Thermal Hazard Mitigation and Smoke Control by Water Mist and Semi-Transverse Mechanical Ventilation for Battery Electric Vehicle Fires in Road Tunnels

Battery electric vehicle (BEV) fires in road tunnels can intensify thermal, smoke transport, visibility, and CO exposure hazards under confined ventilation. This study evaluated the combined mitigation performance of water mist and semi-transverse mechanical ventilation. A three-...