Research works

PHYTOCHEMICAL INVESTIGATION AND IN VITRO ANTI-OXIDANT AND ANTI-INFLAMMATORY ACTIVITIES OF LIMONIA ACIDISSIMA

This study explores the phytochemical profile and biological activities of Limonia acidissima (Wood Apple) root extract. Ethanolic extraction revealed the presence of alkaloids, flavonoids, saponins, phenols, and glycosides. Quantitative assays confirmed high phenolic and flavono...

PATTERN OF URINARY INCONTINENCE AMONG WOMEN AT AGE OF 45 YEAR AND OLDER IN PRIMARY HEALTH CENTERS IN MOSUL CITY

Background: The integration of electronic health (e-health) and digital medical resources into medical education has transformed healthcare delivery and training, yet awareness, usage, and challenges surrounding their adoption among medical students, particularly in low- and midd...

DIGITAL HEALTH SUPPORTED ADVERSE DRUG REACTION REPORTING AMONG ELDERLY PATIENTS RECEIVING CARDIOVASCULAR

Background: Elderly patients receiving cardiovascular medications are vulnerable to adverse drug reactions (ADRs) because of ageing-related physiological changes, multimorbidity, polypharmacy, and long-term medication exposure. Conventional ADR reporting may miss mild, delayed, o...

FUNCTIONAL OUTCOME OF STEROID INJECTION IN MANAGING DE QUERVAIN'S TENOSYNOVITIS

De Quervain’s tenosynovitis is a stenosing tenosynovitis of the first dorsal compartment of the wrist, caused by thickening and myxoid degeneration of the tendon sheaths surrounding the abductor pollicis longus and extensor pollicis brevis tendons; corticosteroid injection is wid...

EXAMINATION OF THE ISOSTERE AND BIOISOSTERE SUBSTITUTIONS IN STRUCTURES OF GEMCITABINE, CAPECITABINE, AND PACLITAXEL: THREE AGENTS UTILIZED FOR TREATMENT OF PANCREATIC CANCER

This study presents analysis of isosteres and bioisosteres of gemcitabine, capecitabine, and paclitaxel, which are utilized in the clinical treatment of pancreatic cancer. Pancreatic cancer most commonly occurs (90%) in the form of adenocarcinoma (ductal carcinoma). This is an ag...

A COMPARATIVE STUDY FOR THE EVALUATION OF FOUR DIFFERENT BRANDS OF ORAL ANTI DIABETIC DRUG "GLIMEPIRIDE 1 MG"

The objective of this research work was to formulate and comprehensively evaluate glimepiride tablets utilizing the uncoated tablets. Tablets represent the most widely prescribed solid oral dosage form owing to their dosing accuracy, physical stability, and ease of manufacturing....

A PROSPECTIVE OBSERVATIONAL STUDY ON EVALUATION OF RATIONAL USE OF ANTIBIOTICS, OUTCOME AND IMPACT OF PATIENT EDUCATION ON MEDICATION ADHERENCE AND QUALITY OF LIFE IN PNEUMONIA PATIENTS IN A TERTIARY CARE HOSPITAL: A PILOT STUDY.

Background: Pneumonia is a major cause of morbidity and mortality worldwide and is commonly treated with antibiotics. Irrational antibiotic use contributes to antimicrobial resistance, prolonged hospitalization, increased healthcare costs, and poor clinical outcomes. Clinical pha...

PHYSICOCHEMICAL EVALUATION AND HPTLC FINGERPRINTING OF VIPAREETA MALLA TAILA AND ITS OINTMENT FORMULATION

Background: Vipareeta Malla Taila, a classical Ayurvedic oil-based formulation described in Chakradatta under Vrana Shotha Adhikara, is traditionally indicated for the management of Vrana. Modification of traditional dosage forms into patient-friendly formulations, such as ointme...

ASSESSMENT OF THERAPEUTIC NON - COMPLIANCE AMONG TYPE 2 DIABETES MELLITUS PATIENTS

Therapeutic Non - Compliance can be defined as the failure of a patient to correctly adhere to their prescribed healthcare plan. This includes missing medication doses, treatment schedules alteration or failing to follow recommended lifestyle changes. Therapeutic Non – Compliance...

COLORIMETRIC DETERMINATION OF DICLOFENAC POTASSIUM IN TABLET DOSAGE FORM USING BROMOCRESOL GREEN AS A CHROMOGENIC REAGENT

Objective: The primary goal of this study is to use the colorimetric approach to estimate the dosage of Diclofenac potassium in tablet dosage form. The developed approach has been validated in accordance with ICH Q2(R2) requirements. Methods and materials: Chromatographic quantif...

MATERNAL AND PERINATAL OUTCOME IN WOMEN WITH OVARIAN TUMORS COMPLICATING PREGNANCY

Background: Ovarian tumors during pregnancy are uncommon and pose significant diagnostic and therapeutic challenges because of physiological changes associated with pregnancy and the need to optimize both maternal and fetal outcomes. While most adnexal masses are benign, timely i...

STABILITY STUDIES OF PHARMACEUTICALS DOSAGE FORM

Stability Studies-The cornerstone of Pharmaceutical Product Development An Introduction Abstract. Pharmaceutical stability studies are crucial for guaranteeing that medicinal products remain safe, efficacious and of good quality throughout their entire proposed shelf life. Such s...

ARTIFICIAL INTELLIGENCE IN HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY: TRANSFORMING METHOD DEVELOPMENT, OPTIMIZATION, AND DATA ANALYSIS- A COMPREHENSIVE REVIEW

High-Performance Liquid Chromatography (HPLC) is a critical analytical technique for separating, identifying, and quantifying compounds, but traditional gradient method development is resource-intensive and time-consuming. This review explores the integration of artificial intell...

FORMULATION AND EVALUATION OF POLYHERBAL FACIAL SCRUB

The Importance of Cosmetics has increased as many people want to stay young and attractive. There are many products available in market regarding skin care and face care. Scrub is one of the products which is used to cure different types of skin conditions, such as acne, aging, r...

THE AGNI–GUT MICROBIOME AXIS: BRIDGING AYURVEDIC CONCEPTS WITH CONTEMPORARY MICROBIOME SCIENCE – A NARRATIVE REVIEW

Digestion and metabolism are essential processes that regulate immune function, metabolic balance, and overall health. Recent research has identified the gut microbiome as a key regulator of these functions, while Ayurveda recognizes Agni as the fundamental principle governing di...

COMPREHENSIVE REVIEW OF ANALYTICAL METHODS FOR THE DETERMINATION OF PRAZOSIN HYDROCHLORIDE IN PHARMACEUTICAL FORMULATION

Prazosin Hydrochloride (Prazosin HCl) is a selective α1-adrenergic receptor antagonist widely used in the management of hypertension, benign prostatic hyperplasia, and post-traumatic stress disorder-related nightmares. Accurate and reliable analytical methods are essential for th...

A CASE STUDY ON THE EFFICACY OF DHANYAKA-GOKSHURA GHRITA AND VARUNADI KWATH IN THE MANAGEMENT OF VATASTHEELA W.S.R. TO BENIGN PROSTATE HYPERPLASIA

Benign Prostatic Hyperplasia (BPH) is a prevalent condition in aging males, significantly impacting quality of life. In Ayurveda, this condition closely resembles Vatastheela, a type of Mutraghata characterized by urinary obstruction due to a granthi (nodular growth) in the basti...

EFFECT OF SUPPLEMENTING CERTAIN ORGANIC ACIDS TO BROILER DIETS ON SOME BLOOD PARAMETERS

An experiment was conducted to study the effect of adding certain organic acids to broiler feed mixtures on blood parameters. The experiment lasted for 40 days, using 150 one-day-old chicks of the (ROSS 308) hybrid, distributed into five treatments. Each treatment contained 30 bi...

UNDERSTANDING OF PRIMARY OPEN ANGLE GLAUCOMA IN GENERAL PERSPECTIVE: A REVIEW ARTICLE WITH SPECIAL REFERENCE TO KAPHAJA ADHIMANTHA

Glaucoma is a chronic, progressive optic neuropathy characterized by structural damage to the optic nerve head and corresponding visual field defects, often associated with raised intraocular pressure (IOP). It is one of the leading causes of irreversible blindness worldwide and...

MATERIALS FOR 3D PRINTING IN PROSTHODONTICS: ADVANTAGES AND DISADVANTAGES

Three-dimensional (3D) printing is a major innovation in digital prosthodontics, enabling the creation of accurate, customized dental restorations. The success of this technology relies heavily on the materials used, as their properties—physical, mechanical, biological, and aesth...