Research works

Articulating Hem-o-Lok–assisted single-position laparoscopic nephroureterectomy for UTUC: a feasibility study with preliminary oncological outcomes

Radical nephroureterectomy (RNU) with bladder cuff excision is the standard treatment for high-risk non-metastatic upper tract urothelial carcinoma (UTUC). This feasibility-oriented study aimed to describe articulating Hem-o-Lok–assisted single-position laparoscopic nephrouretere...

Effect of motivational interviews and peer education on adherence to pre-exposure prophylaxis among key populations in Kisangani: a randomized clinical trial

The present study aimed to evaluate the effect of motivational interviews and peer education on adherence to pre-exposure prophylaxis (PrEP) among key populations in Kisangani. This study utilizes a randomized controlled trial design to assess the effect of motivational interview...

Learning a unified graph transformer with mamba-based dynamic state evolution for 3D multi-object tracking

Abstract 3D multi-object tracking is crucial for autonomous driving, providing environmental sensing. To enhance multi-type tracking cues, we introduce DUG-Track (Dynamic Unified Graph Tracker), a novel tracker that pioneers a deeply integrated framework of dynamic state evolutio...

Targeting the immune-metabolic axis reverses orthodontics-induced systemic pathology

Orthodontic treatment corrects various craniofacial malformations primarily through triggering active alveolar bone remodeling, however the potential impacts of this intervention on the systemic immune state have long been insufficiently explored. Here, we show that mechanical fo...

Development of a teacher-delivered, school-based mental health promotion programme for adolescents in China: a Delphi study

Strengthening social and emotional competencies (SECs) is a promising upstream strategy for adolescent suicide prevention. However, the existing school-based programmes cannot be directly transplanted into the Chinese school environment. It could be attributed to the different ps...

Factors associated with prolonged hospital stay in mandibular condylar fractures: a multicenter retrospective study in Indonesia

Mandibular condylar fractures constitute a significant proportion of maxillofacial trauma and are associated with functional impairment and increased healthcare utilization. However, factors associated with the duration of hospital stay remain insufficiently understood, particula...

First detection of Leishmania infantum in dogs and wild-caught Culicoides oxystoma in Hainan Province, Southern China

Leishmaniases are neglected parasitic diseases expanding globally. In China, Leishmania infantum , which isendemic in the west, has reemerged and spread to the central part of the country, raising concerns about further potential expansion. Given limited data from southern China,...

Sustainable ammonia synthesis from nitrate wastewater via graphdiyne Mo–Cu–C≡C interfaces

Electrochemical green ammonia (NH3) production using renewable electricity is sustainable but suffers from selectivity-activity-stability trade-off under industrial conditions. Here we report an atomic interface engineering strategy enabling in-situ assembly and coupling of hexae...

Consent: Doctor, can you please do my operation?

The evolution of informed consent Globally, despite extensive written guidance, landmark legal cases, and evolving clinical practices, the landscape of informed consent remains uncertain for both patients 1 and doctors. 2 The notion of informed consent was thrust upon medicine by...

Development of an ethical resolution process and education resources: supporting equity-focused public health ethics education through community-engaged research

Healthcare ethics education is essential for supporting trainees and health professionals to build ethical reasoning skills necessary to resolve complex ethical issues, support equitable health outcomes, and promote just healthcare systems. Traditional ethical decision-making fra...

A NEW MORE ACCURATE HILBERT-TYPE INEQUALITYINVOLVING ONE PARTIAL SUM

By using the weight coefficients, the Euler-Maclaurin summation formula and Abel summation by parts formula, a new more accurate Hilbert-type inequality with the power function as the internal variables involving one partial sum is given. The equivalent conditions of the best val...

Exploratory Assessment of Ionic Liquid-Based Molecularly Imprinted Polymers for Potential Acrylamide Binding from Coffee Beverage

Acrylamide (AA) is a heat-induced process contaminant of toxicological concern associated with potential health risks. Its selective removal from complex food matrices, such as coffee brew, while preserving quality, remains a major technological challenge. This study explored an...

CO2 laser processing of fused silica: a review of mechanisms, defect control and functionalization

Fused silica optics are critical components in inertial confinement fusion facilities, where they are exposed to intense ultraviolet laser radiation. However, processing induced subsurface defects serve as laser damage precursors, severely degrading the laser-induced damage thres...

Sensitivity of Fusarium graminearum to propiconazole and potential resistance mechanisms

Fusarium head blight (FHB), caused by Fusarium graminearum , is a globally significant fungal disease affecting wheat and barley crops. Chemical fungicides remain the primary control method. However, fungicide resistance remains a big challenge. This study assessed the sensitivit...

Iron oral supplementation in anemic patients undergoing orthopedic prosthetic surgery: a randomised trial comparing short_term and prolonged administration regimen

Preoperative anaemia in patients undergoing major elective orthopaedic surgery is a relatively frequent condition and is associated with perioperative transfusions. The aim of the present study was to investigate the efficacy of liposomal iron, folic acid, and vitamins in reducin...

Latent profiles of health empowerment and associated factors among older adults hospitalised with stroke: a single-centre cross-sectional study

This study aims to explore the health empowerment of elderly ischemic stroke patients in China and analyze its associated factors. Ischemic stroke patients hospitalized in the Department of Neurology and Rehabilitation of a tertiary hospital in Daqing from June 2025 to March 2026...

The VASN-YAP-MYL9 axis drives M2-like macrophage polarization and immune evasion in colorectal cancer

Tumor-associated macrophages (TAMs) polarized toward an M2-like phenotype are critical drivers of immunosuppression in colorectal cancer (CRC). While Vasorin (VASN) is implicated in poor prognosis, its specific role in orchestrating the tumor immune microenvironment remains elusi...

Uncertainty-aware electrification of university campuses: Matching demand with renewable generation for zero emissions

Urban decarbonization requires robust methodologies to match electrified demand with on-site renewable generation under operational variability. University campuses are particularly well-suited testing environments, as their predominantly daytime demand profiles favor solar photo...

Evaluating the effectiveness of the SPICES model in enhancing students’ learning experience in social medicine and public health field training at jiroft university of medical sciences, Iran

Although the SPICES framework is well established for guiding curriculum renewal in medicine, its real-world application within Social Medicine placements and Public Health practicums has not been thoroughly investigated—particularly in Iran. In our context, these courses still r...

MINK1 inhibition suppresses triple-negative breast cancer by abrogating ALDOA S39 phosphorylation and reprogramming glucose metabolism

Triple negative breast cancer (TNBC) represents the most malignant subtype of breast cancer, with heightened invasiveness, frequent recurrence and poor prognosis. Deciphering the molecular mechanisms underlying TNBC pathogenesis and drug resistance is critical for developing prec...