Research works

Duration of Therapeutic Hypothermia After Out-of-Hospital Cardiac Arrest

Importance Therapeutic hypothermia is widely used for neuroprotection following cardiac arrest, but clinical trials have not consistently demonstrated improved neurological outcomes, and the optimal duration of cooling remains uncertain. Objective To determine the duration of the...

Mechanistic insights into the immunomodulatory and antibacterial activity of the Japanese Kampo Formula Hainosankyuto

Purpose This study aimed to quantify the in vitro antibacterial activity of the Japanese herbal formula Hainosankyuto (HNST) against Gram-positive and Gram-negative bacteria and to elucidate its immunomodulatory effects on human monocytes. Methods The antibacterial activity of HN...

How Inflation Ends Is How Matter Generation Begins: An N-Body Embedding of the Universal Interaction with No Timing Rule, and an End-to-End Genesis Run

Two preceding papers each supplied half of a story: the onset-mode paper gave the way a universe begins (only unstable self-consistent closures undergo latent exponential amplification, ending in a three-direction metastable structure) but no matter; the two-body paper gave the g...

On the Effects of Spaced Versus Massed Practice on Deliberate Learning of English Idioms across L2 Proficiency Levels

This study investigated the effects of spaced versus massed practice on the deliberate learning of English opaque idioms across different second language (L2) proficiency levels. A total of 199 Iranian EFL learners at different proficiency levels were taught 40 opaque idioms unde...

Pure W-Expansion / NecroGraft: Full-Rank Weight Growth for Zero-Forgetting Model Adaptation

I present Pure W-Expansion (NecroGraft), a weight-adaptation method that augments frozen pretrained models with full-rank trainable expansion matrices, enabling domain specific learning without catastrophic forgetting. Unlike Low-Rank Adaptation (LoRA), which approximates weight...

Serotonergic Antidepressant Use Is Not Associated with Increased Revision but Alters Postoperative Pain Following Rotator Cuff Repair

Rotator cuff tears are common, and although surgical repair is frequently performed, re-tear and complication rates remain substantial. The impact of selective serotonin reuptake inhibitors (SSRIs) and serotonin–norepinephrine reuptake inhibitors (SNRIs) on postoperative outcomes...

Representations of Indefinite Integrals Involving Exceptional Orthogonal Polynomials in Terms of Wronskians and Parameter Derivatives

We construct classes of indefinite integrals that involve exceptional orthogonal polynomials of Laguerre, Jacobi, or Hermite types. By means of a recently devised method, these integrals can be represented in closed form. As a byproduct, we obtain integrals that involve confluent...

Risk Assessment of Post-Earthquake Gas Explosion Disaster Chains in High-Rise Residential Buildings: A Fuzzy Bayesian and Complex Network Approach

To address the challenges in risk prevention and control of post-earthquake gas explosions in high-rise buildings and the deficiencies of traditional methods in handling uncertainty, this paper conducts a risk evolution analysis from the perspectives of fuzzy Bayesian networks (F...

Factors affecting job choices among primary health workers in China: a discrete choice experiment study

Primary health workers (PHWs) are crucial for primary health care, yet shortages and maldistribution persist in China. The study aimed to quantify their job preferences and the importance of key job attributes to inform attraction and retention policies. A discrete choice experim...

Radiologic Presentation of Invasive Ductal and Lobular Breast Carcinoma: A Single-Center Experience from Oman

Breast cancer is the most commonly diagnosed cancer among women worldwide and remains a leading cause of cancer-related mortality. The most frequent histological subtypes are invasive ductal carcinoma (IDC) and invasive lobular carcinoma (ILC), which demonstrate different biologi...

The Permeable Lip: A Critical Knowledge Gap for Systemic Exposure to Lip Cosmetic Chemicals

The pervasive use of lip cosmetics results in chronic, low-dose exposure to complex mixtures of chemicals via multiple routes, yet current cosmetic safety regulations treat lip products as conventional topical applications to skin. While the EU safety assessment framework acknowl...

Pollution transport and transformation over the Po Plain as revealed by airborne and ground-based measurements in July 2017 during EMeRGe

Airborne measurements provide valuable information about the vertical distribution of pollutants enabling the complex transport and dispersion pathways within and above the boundary layer (BL) to be investigated. In this study, the transport of pollution within the Po Plain, a ma...

Interaction ofFood-Derived Bitter Peptides with hTAS2R4:Recognition and Activation Mechanisms Revealed by Docking and Mutagenesis

Abstract Bitter peptides (BPs) have a wide range of applications in the food and pharmaceutical industries. This study identified four food-derived BPs (TPLVDR, VLY, LEEL, and FYL) as novel agonists of the human bitter taste receptor hTAS2R4, using a rapid cell-based screening ap...

Microwave ablation for selective fetal reduction in complicated monochorionic diamniotic twin pregnancies: Experience from a single tertiary center

Abstract Objective To investigate the use of microwave ablation (MWA) for selective fetal reduction in monochorionic twin pregnancies. Methods This retrospective, single‐center case series included consecutive monochorionic diamniotic twin pregnancies that underwent selective fet...

Successful macroscopic penile replantation in a 4-year-old child: a case report

Abstract Background Penile amputation is a rare urological emergency that requires prompt surgical intervention and comprehensive medical evaluation. Microsurgical replantation is considered the preferred approach when feasible; however, macroscopic repair may provide satisfactor...

Astrobios Dream Resonance Hypothesis (ADRH)

Dreams remain one of the most complex and least understood phenomena in neuroscience and consciousness research. Contemporary scientific theories primarily explain dreams as products of neural activity associated with memory consolidation, emotional regulation, predictive process...

Quantifying the Gap Between the Local Perceptions of Farming Households and What Experts Say About Climate Change in Haiti and the Dominican Republic

This study quantifies and assesses the gap between the perceptions of 550 farming households on the Caribbean island of Hispaniola and the opinions of 60 regional experts on climate change. This quantification draws on the traditional knowledge of farming households, which is bas...

Elucidating the Impact of Bacterial Composition and Diversity on Skin Homeostasis Using a Human 3D In Vitro Skin Model

The importance of the skin microbiome in human health has become increasingly evident. Despite considerable advancements, complex host–microbe interactions remain largely unexplored, primarily due to a paucity of models mimicking human skin and maintaining bacterial diversity in...

EuroMillions Breakthrough Mining — 1423 Sources, 9778 Leads Extracted — E8 Intelligence Research

Mined 1423 lottery+quantum breakthroughs. Extracted 9778 leads across 13 categories. 7871 high-value leads found. Categories: {"CORRIDOR": 799, "FORMULA": 651, "GEOMETRIC": 677, "FORWARD_ATTEMPT": 830, "QUANTUM": 1043, "TIMING": 179, "CELESTIAL": 739, "GEMATRIA": 784, "CONSTANT":...

Development and Research of Different Perovskitic Electrocatalysts Synthesized via Co-Precipitation

Reversible solid oxide cells (ReSOCs) represent one of the most promising electrochemical technologies for sustainable energy conversion and storage, yet their large-scale deployment remains constrained by electrode materials capable of sustaining stable performance under alterna...