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Full Plate Living Evaluation and Case Series

Dietary interventions can improve cardiometabolic health, however, affordability, sustainability, and efficacy remain a challenge. Full Plate Living (FPL) is a free, virtual, research-based, experience-centered nutrition program that has been shown to improve health. Here, we des...

A Pan-Cancer Target Trial Emulation of Exercise and Distant Disease-Free Recurrence

BACKGROUND: We leveraged observational data to conduct a target trial emulation (TTE) framework evaluating the association of exercise on distant disease-free survival (DDFS) in a pan-cancer cohort. METHODS: To emulate a randomized controlled trial (RCT), a "historical" exercise...

Quantum Fractal Dynamics from Complex Relativistic Kinematics

We establish an exact mathematical isomorphism mapping special relativistic kinematics in complex velocity space directly to microscopic quantum fractal trajectories ($\Delta x \sim \sqrt{\Delta t}$) and local spacetime geometry. Guided by the principle that scale transformations...

Mechanism and Application of Biochar as an Electron Shuttle in the Remediation of Soil Pollutants

Biochar has attracted increasing attention in soil remediation due to its porous structure, abundant surface functional groups, and environmental compatibility. Beyond its conventional roles as an adsorbent and soil amendment, biochar has increasingly been recognized as an electr...

Association between cardiometabolic index and incident electrocardiographic abnormalities in older adults

Electrocardiographic (ECG) abnormalities are important predictors of cardiovascular events in older adults, yet their early identification remains challenging. The cardiometabolic index (CMI), which integrates central obesity and lipid metabolism, has emerged as a potential marke...

CMV PCR Monitoring for Hematological Malignancy

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Health-Related Quality of Life of Patients with Epidermolysis bullosa and Carers Using a Time Trade-Off Approach in the UK General Population to Elicit Utilities for Health Technology Assessment

Background: Epidermolysis bullosa (EB) is a complex group of rare, inherited skin disorders that blister easily, imposing substantial burden on patients and carers. There is a lack of published evidence in the UK quantifying health-related quality of life in EB patients and carer...

Fuzzy Congruences on Heyting Algebras: Characterizations via Fuzzy Ideals and Filters.

<ns5:p>Background Heyting algebras serve as algebraic models for intuitionistic logic, with classical congruence relations playing a key role in their structural analysis. This paper extends classical congruence theory to the fuzzy setting, motivated by the need to handle gradati...

Axiomatic System and Core Constants of Discrete Variable Lattice Dissipative Functionals Well-Posedness Proof of Discrete Dissipative Helmholtz Problem on Finite Hierarchical Fractal Lattice

Abstract This paper constructs an axiomatic mathematical framework for discrete variable lattice dissipative functionals. Utilizing four mutually independent fundamental axioms as a minimal complete basis, it systematically investigates the operator properties, steady-state struc...

RETHINKING DEMOCRATIC GOVERNANCE AND INCLUSION OF LOCAL GGOVERNMENT IN POLITICS IN NIGERIA

Democracy has been observed as the only acceptable way of enhancing governance in all countries of the world, including Nigeria. The idea of democracy permits or allows for the majority participation or inclusion of localities in governance and guarantees the strict adherence to...

On Leonardo’ choice to depict a wingless blister beetle producing a sexual stimulant

A largely overlooked drawing of a blister beetle belonging to the genus Meloe made by Leonardo da Vinci is discussed. An array of hypotheses about the reasons for portraying such an insect are briefly put forward, including that of an interest for the beetle as an aphrodisiac.

HIV Pre-Exposure Prophylaxis Use Among South Asian Sexual Minority Men in the United States: Pilot Web-Based Survey Study

Abstract Background South Asian American gay, bisexual, and other men who have sex with men (GBM) experience multiple minority stressors, such as internalized homophobia, racial prejudice, and homonegative discrimination, thereby elevating their risk of HIV. Due to the scarcity o...

EuroMillions Breakthrough Mining — 1693 Sources, 12432 Leads Extracted — E8 Intelligence Research

Mined 1693 lottery+quantum breakthroughs. Extracted 12432 leads across 13 categories. 10446 high-value leads found. Categories: {"CORRIDOR": 1032, "FORMULA": 876, "GEOMETRIC": 718, "FORWARD_ATTEMPT": 1081, "QUANTUM": 1294, "TIMING": 204, "CELESTIAL": 960, "GEMATRIA": 1028, "CONST...

Quartz Optimizer: Robust Gradient Shaping and Bounded Adaptive Steps for Stable Deep Learning Training

Optimization plays a critical role in training deep neural networks, directly impacting convergence speed, model generalization, and stability. While existing methods such as stochastic gradient descent (SGD) and adaptive optimizers like Adam and AdamW have achieved significant s...

Biomarker-Stratified Phase II Trial of Trastuzumab Rezetecan in Advanced Salivary Gland Carcinoma Across Cohorts With High and Low Human Epidermal Growth Factor Receptor 2 Expression

PURPOSE Systemic treatment options for advanced salivary gland carcinoma (SGC) are limited, and prospective data for human epidermal growth factor receptor 2 (HER2)–directed therapy remain sparse, particularly in HER2-low disease. We evaluated trastuzumab rezetecan (SHR-A1811), a...

EVALUATION OF ANTIBIOTIC SUSCEPTIBILITY PROFILES IN BACTERIAL ISOLATES FROM URINARY TRACT INFECTIONS

Background: Urinary tract infections (UTIs) represent prevalent bacterial infections globally, with a higher incidence observed in females and individuals with compromised immune systems. The increasing prevalence of antimicrobial resistance (AMR) among uropathogens complicates t...

MdSPL1‐MdNF‐YB4‐MdCKX7 Module Positively Regulates Saline‐Alkali Tolerance by Mediating Cytokinin Levels in Apple

Saline-alkali stress is a major abiotic factor that compromises plant growth, crop yield, and quality. Cytokinin plays an essential role in plant responses to saline-alkali stress; however, the underlying molecular mechanisms remain unclear in apple (Malus domestica). In this stu...

What Judgment Forgets: Affective Heteronomy and the Asymmetry of Answerability in Digital Capitalism

Contemporary critiques of digital capitalism have examined behavioural data extraction, algorithmic governance, attention capture, and platform regulation, while debates about responsibility have generally focused further downstream on consent, moderation, and individual conduct....

Mobility and Roman Britannia

Abstract This article reviews the evidence for mobility within, and into, the Roman province of Britannia, assesses the current state of the field and sets out how current approaches should be developed and improved. Mobility was foundational to the Roman empire and its provinces...

Fractal Judas survivor: EURJPY DAILY rung — E8 Intelligence Research

Configuration survived the two-half honesty test on 2 years of M1 data. Rung=DAILY, cost model=ecn, entry=wick, SL buffer=2.0 pips, TP=full range, sweep depth filter=0.0, tide alignment=week_against. 174 trades, +3.00 pips/trade expectancy after costs, profit factor 1.80 (year 1)...